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NASA NTRS2009

The Unique Capabilities of the Global Hawk Aircraft for the Study of Climate Changes

Due to unprecedented extent and flexibility of the coverage that is now attainable both in space and time, stratospheric unmanned aircraft, such as the Global Hawk (GH), offers new opportunities for the study of climate changes. The capability of performing long flights at altitudes close to the boundary conditions of radiative processes, and of following the diurnal variation of chemical species and clouds, make the GH competitive with LEO and geosynchronous satellites, and even capable of new observations that are not possible from satellites. This paper discusses how the GH can be used to make relevant advancements in most of the issues that are related to climate change studies, such as: Earth Radiation Budget, Water Cycle, Ecosystems and Upper Troposphere-Lower Stratosphere, as well as to the monitoring and control of Greenhouse Gases and Air Quality . Collaboration between NASA and Italian scientific institutions, within the framework of the US.-Italy Cooperation on Climate Change, is providing the opportunity to rapidly deploy new instruments on the GH and to possibly operate the aircraft from an Italian site in the Mediterranean area. From this area, which is considered highly vulnerable to climate change, meridional transects would allow the crossing of Polar and Sub Tropical Jets, as well as a complete crossing of the Inter Tropical Convergence Zone, while latitudinal ones would follow the influx from Asia and North America. Regions otherwise difficult to access, such as Central Africa and the Tibetan Plateau, could be reached and better investigated. An overview of these new opportunities will be given and discussed.

Cairo, F.↗

NASA NTRS2014

HEMODOSE: A Set of Multi-parameter Biodosimetry Tools

There continues to be important concerns of the possibility of the occurrence of acute radiation syndromes following nuclear and radiological terrorism or accidents that may result in mass casualties in densely populated areas. To guide medical personnel in their clinical decisions for effective medical management and treatment of the exposed individuals, biological markers are usually applied to examine radiation induced biological changes to assess the severity of radiation injury to sensitive organ systems. Among these the peripheral blood cell counts are widely used to assess the extent of radiation induced bone marrow (BM) injury. This is due to the fact that hematopoietic system is a vulnerable part of the human body to radiation damage. Particularly, the lymphocyte, granulocyte, and platelet cells are the most radiosensitive of the blood elements, and monitoring their changes after exposure is regarded as a practical and recommended laboratory test to estimate radiation dose and injury. In this work we describe the HEMODOSE web tools, which are built upon solid physiological and pathophysiological understanding of mammalian hematopoietic systems, and rigorous coarse-grained biomathematical modeling and validation. Using single or serial granulocyte, lymphocyte, leukocyte, or platelet counts after exposure, these tools can estimate absorbed doses of adult victims very rapidly and accurately to assess the severity of BM radiation injury. Some patient data from historical accidents are utilized as examples to demonstrate the capabilities of these tools as a rapid point-of-care diagnostic or centralized high-throughput assay system in a large-scale radiological disaster scenario. HEMODOSE web tools establish robust correlations between the absorbed doses and victim's various types of blood cell counts not only in the early time window (1 or 2 days), but also in very late phase (up to 4 weeks) after exposure.

Hu, Shaowen↗

NASA NTRS2020

Near 40 Years MERRA-2 Data at NASA GES DISC -Opportunity and Challenge to Support Extremes Study

To the end of 2019, 40 years NASA climate reanalysis data sets from the Modern Era Retrospective-analysis for Research and Applications, Version 2 (MERRA-2) will be available at NASA Goddard Earth Sciences Data and Information Services Center (GES DISC). MERRA-2 consists atmosphere, land, and ocean data, which may be used for the studies ranging from the short scale weather events to the large scale decadal vulnerabilities. The hourly products, such as precipitation, soil moisture, temperature, and aerosols etc., have been used widely to study extreme events.In supporting users from broad communities, GES DISC have developed various data access services, including subsetter for downloading only data of interest with preferred format; OPeNDAP - for machine-to-machine data access; and Giovanni- for online visualization and analysis, etc. A big challenge for extreme study is to downloading and processing long-term hourly or daily data. The data downloading performance is not very satisfied by many users with current services and the native archived data structure. Late June 2019, many people in Europe had experienced extreme heat waves. The temperatures in several countries exceeded 40°C (104°F). For example, MERRA-2 shows that the near surface daily maximum temperature of June 28 2019 over Marseille, a city in southern France, reached 41.1 °C (106°F), which is the record breaking temperature in the last 40 years. GES DISC is working together with domain science experts to improve the performance of long time series access, making analysis ready data sets in supporting application researches, such as extreme study. In this presentation, using Europe heat wave as an example, we will show prototype of the in developing service for finding extremes from near 40 years MERRA-2 data at a given location. MERRA-2 data can be accessed from NASA GES DISC(https://disc.gsfc.nasa.gov/ ) by search keyword "MERRA-2".

Shen, Suhung↗

NASA NTRS2017

An Automaton Rover Enabling Long Duration In-Situ Science in Extreme Environments

The Automaton Rover for Extreme Environments (AREE) is a NASA Innovative Advanced Concept (NIAC) funded study focused on enabling long duration science on Venus by replacing vulnerable electronics with an entirely mechanical design. By utilizing high temperature alloys, the rover would survive on the surface of Venus for weeks if not months. The rover concept harvests wind energy using a turbine and stores it in a constant force spring. The mobility system would be guided by a mechanical computer and logic system, programed to carry out the mission. It would collect basic science data such as wind speed, temperature, and seismic events. Communicating the data back to Earth is the most challenging aspect of the system design with multiple options being explored in a trade: a simple electronic high temperature transponder, a retroreflector target or inscribing phonograph style records to be launched via a balloon to a high altitude drone capable of transmitting the data back to Earth. AREE is not only a new exciting in-situ rover concept, but also a paradigm shift to conducting in-situ science in extreme environments. Traditional extreme environment vehicles collect as many diverse data points as possible in the short period of time before system failure. AREE breaks that trend by exploring what can be done with only a few basic scientific measurements, but recorded over long periods of time. In addition to Venus, the concept can be useful in other extreme environments in the solar system including Mercury, Jupiter's radiation belts, the interiors of gas giants, the mantle of the Earth and volcanoes throughout the solar system.

Parness, Aaron↗

NASA NTRS2020

Global Declines in Human-Driven Mangrove Loss

Global mangrove loss has been attributed primarily to human activity. Anthropogenic loss hotspots across Southeast Asia and around the world have characterized the ecosystem as highly threatened, though natural processes such as erosion can also play a significant role in forest vulnerability. However, the extent of human and natural threats has not been fully quantified at the global scale. Here, using a Random Forest-based analysis of over one million Landsat images, we present the first 30-meter resolution global maps of the drivers of mangrove loss from 2000-2016, capturing both human-driven and natural stressors. We estimate that 62% of global losses between 2000-2016 resulted from land-use change, primarily through conversion to aquaculture and agriculture. Up to 80% of these human-driven losses occurred within six Southeast Asian nations, reflecting the regional emphasis on enhancing aquaculture for export to support economic development. Both anthropogenic and natural losses declined between 2000-2016, though slower declines in natural loss caused an increase in their relative contribution to total global loss area. We attribute the decline in anthropogenic losses to the regionally-dependent combination of increased emphasis on conservation efforts and a lack of remaining mangroves viable for conversion. While efforts to restore and protect mangroves appear to be effective over decadal time scales, the emergence of natural drivers of loss presents an immediate challenge for coastal adaptation. We anticipate that our results will inform decision making within conservation and restoration initiatives by providing a locally-relevant understanding of the causes of mangrove loss.

Coastal wetlands↗

NASA NTRS2011

Atmospheric Chemistry Over Southern Africa

During the southern African dry season, regional haze from mixed industrial pollution, biomass burning aerosol and gases from domestic and grassland fires, and biogenic sources from plants and soils is worsened by a semi-permanent atmosphere gyre over the subcontinent. These factors were a driver of several major international field campaigns in the 1990s and early 2000s, and attracted many scientists to the region. Some researchers were interested in understanding fundamental processes governing chemistry of the atmosphere and interaction with climate change. Others found favorable conditions for evaluating satellite-derived measurements of atmospheric properties and a changing land surface. With that background in mind a workshop on atmospheric chemistry was held in South Africa. Sponsored by the International Commission for Atmospheric Chemistry and Global Pollution (ICACGP; http://www.icacgp.org/), the workshop received generous support from the South African power utility, Eskom, and the Climatology Research Group of the University of the Witwatersrand, Johannesburg, South Africa. The purpose of the workshop was to review some earlier findings as well as more recent findings on southern African climate vulnerability, chemical changes due to urbanization, land-use modification, and how these factors interact. Originally proposed by John Burrows, president of ICACGP, the workshop was the first ICACGP regional workshop to study the interaction of air pollution with global chemical and climate change. Organized locally by the University of the Witwatersrand, the workshop attracted more than 60 delegates from South Africa, Mozambique, Botswana, Zimbabwe, France, Germany, Canada, and the United States. More than 30 presentations were given, exploring both retrospective and prospective aspects of the science. In several talks, attention was focused on southern African chemistry, atmospheric pollution monitoring, and climate processes as they were studied in the field campaigns such as Transport and Atmospheric Chemistry Near the Equator-Atlantic (TRACE-A), Southern African Fire-Atmosphere Research Initiative (SAFARI-92), and Southern African Regional Science Initiative (SAFARI 2000). Since those large international efforts, satellites have matured enough to enable quantifiable measurements of regional land surface, atmosphere, and ocean. In addition, global and chemical transport models have also been advanced to incorporate various data. Thus, the timing of the workshop was right for a full-fledged re-assessment of the chemistry, physics, and socio-economical impacts caused by pollution in the region, including a characterization of sources, deposition, and feedbacks with climate change.

Gatebe, Charles K.↗

NASA NTRS2018

Developing Land Use Land Cover Maps for the Lower Mekong Basin to Aid Hydrologic Modeling and Basin Planning

This paper discusses research methodology to develop Land Use Land Cover (LULC) mapsfor the Lower Mekong Basin (LMB) for basin planning, using both MODIS and Landsat satellitedata. The 2010 MODIS MOD09 and MYD09 8-day reflectance data was processed into monthlyNDVI maps with the Time Series Product Tool software package and then used to classify regionallycommon forest and agricultural LULC types. Dry season circa 2010 Landsat top of atmosphere reflectance mosaics were classified to map locally common LULC types. Unsupervised ISODATAclustering was used to derive most LULC classifications. MODIS and Landsat classifications werecombined with GIS methods to derive final 250-m LULC maps for Sub-basins (SBs) 1â€“8 of the LMB.The SB 7 LULC map with 14 classes was assessed for accuracy. This assessment compared randomlocations for sampled types on the SB 7 LULC map to geospatial reference data such as Landsat RGBs,MODIS NDVI phenologic profiles, high resolution satellite data, and Mekong River Commissiondata (e.g., crop calendars). The SB 7 LULC map showed an overall agreement to reference data of~81%. By grouping three deciduous forest classes into one, the overall agreement improved to ~87%.The project enabled updated regional LULC maps that included more detailed agriculture LULCtypes. LULC maps were supplied to project partners to improve use of Soil andWater AssessmentTool for modeling hydrology and water use, plus enhance LMB water and disaster managementin a region vulnerable to flooding, droughts, and anthropogenic change as part of basin planningand assessment.

land use land cover mapping; SWAT hydrologic model↗

NASA NTRS2017

Optical Design of the STAR-X Telescope

Top-level science goals of the Survey and Time-domain Astrophysical Research eXplorer (STAR-X) include: investigations of most violent explosions in the universe, study of growth of black holes across cosmic time and mass scale, and measure how structure formation heats majority of baryons in the universe. To meet these goals, the field-of-view of the telescope should be about 1 square-degree, the angular resolution should be 5 arc-seconds or below across large part of the field-of-view. The on-axis effective area at 1 KeV should be about 2,000 sq cm. Payload cost and launch considerations limit the outer diameter, focal length, and mass to 1.3 meters, 5 meters, and 250 kilograms, respectively. Telescope design is based on a segmented meta-shell approach we have developed at Goddard Space Flight Center for the STAR-X telescope. The telescope shells are divided into 30-degree segments. Individual telescopes and meta-shells are nested inside each other to meet the effective area requirements in 0.5 - 6.0 KeV range. We consider Wolter-Schwarzschild, and Modified-Wolter-Schwarzschild telescope designs as basic building blocks of the nested STAR-X telescope. These designs offer an excellent resolution over a large field of views. Nested telescopes are vulnerable to stray light problems. We have designed a multi-component baffle system to eliminate direct and single-reflection light paths inside the telescopes. Large number of internal and external baffle vane structures are required to prevent stray rays from reaching the focal plane. We have developed a simple ray-trace based tool to determine the dimensions and locations of the baffles. In this paper, we present the results of our trade studies, baffle design studies, and optical performance analyses of the STAR-X telescope.

Saha, Timo T.↗

NASA NTRS2017

Design of the STAR-X Telescope

Saha, Timo T.↗

NASA NTRS2014

A Multiple Parameters Biodosimetry Tool with Various Blood Cell Counts - the Hemodose Approach

There continue to be important concerns about the possibility of the occurrence of acute radiation syndromes following nuclear and radiological terrorism or accidents that may result in mass casualties in densely populated areas. To guide medical personnel in their clinical decisions for effective medical management and treatment of the exposed individuals, biological markers are usually applied to examine radiation induced biological changes to assess the severity of radiation injury to sensitive organ systems. Among these the peripheral blood cell counts are widely used to assess the extent of radiation induced bone marrow injury. This is due to the fact that the hematopoietic system is the most vulnerable part of the human body to radiation damage. Particularly, the lymphocyte, granulocyte, and platelet cells are the most radiosensitive of the blood elements, and monitoring their changes after exposure is regarded as a practical and recommended laboratory test to estimate radiation dose and injury. Based upon years of physiological and pathophysiological investigation of mammalian hematopoietic systems, and rigorous coarse-grained bio-mathematical modeling and validation on species from mouse, to dog, monkey, and human, we have developed a set of software tools Hemodose, which can use single or serial granulocyte, lymphocyte, leukocyte, or platelet counts after exposure to estimate absorbed doses of adult victims very rapidly and accurately. Some patient data from historical accidents are utilized as examples to demonstrate the capabilities of these tools as a rapid point-of-care diagnostic or centralized high-throughput assay system in a large-scale radiological disaster scenario. Most significant to the improvement of national and local preparedness of a potential nuclear/radiological disaster, this HemoDose approach establishes robust correlations between the absorbed doses and victim's various types of blood cell counts not only in the early time window (1 or 2 days), but also in the very late phase (up to 4 weeks) after exposure.

Hu, Shaowen↗

NASA NTRSDate not supplied

A Combined Al-Mg/Pb-Pb Age of the Solar System

Astrophysical models of planet formation and protoplanetary disk evolution demand precise and accurate timing of the sequence of events in the solar nebula, relative to a time t=0, usually taken to be during the short epoch of CAI (Ca-rich, Al-rich inclusion) formation. Most CAIs formed withlive26Al (mean-life τ26= 1.034 Myr [1]), with an abundance 26Al/27Al ≈ (26Al/27Al)SS= 5.23 × 10-5[2]. We adopt this as the widespread level of 26Al in the solar nebula at t=0. Assuming spatial homogeneity of 26Al, an inclusion that had less 26Al, (26Al/27Al)0, formed a time Δt26= τ26ln[(26Al/27Al)SS/ (26Al/27Al)0] after t=0.These ages are typical precise to within ±0.1 Myr. Igneous bulk meteorites and inclusions can be relatively dated by the Al-Mg chronometer, but only ifΔt26<6 Myr. The Pb-Pb system is useful as a longer relative chronometer. It yields absolute ages tPb using 207Pb/206Pb, 206Pb/204Pb, and 238U/235U ratios measured indifferent portions of a sample, assuming certain half-lives [4]. These absolute ages are uncertain to within ±9 Myr due to uncertainties in the 235U half-life[3], but times of formation ΔtPb= tCAI–tPb relative to t=0, are more precise(±0.5Myr),iftCAI can be found. Here, tCAI means the Pb-Pb age that would be measured in CAIs using the half-lives the community typically uses, if they achieved isotopic closure at t=0. Unfortunately, direct Pb-Pb dating of CAIs has not definitively determined tCAI. Based on four CAIs with canonical (26Al/27Al)0,[5,6] found tPb= 4567.30 ± 0.16 Myr. No other CAI ages with measured 238U/235U have been reported in the refereed literature, but there are hints of other CAIs with ages tPb= 4568.0 ± 0.2 Myr [7] and tPb= 4568.3 ± 0.2 Myr [8].It is unclear whether anyof these igneous type B CAIs isotopically closed at t=0 or represents tCAI. Instead of measurements, we advocate finding tCAI by minimizing the discrepancies between the Al-Mg and Pb-Pb chronometers. Assuming Δt26=ΔtPb, we find the implied t’CAI= tPb+Δt26, then define t*CAIas the weighted mean of the t’CAI. t*CAIis the best guess for the Pb-Pb age of t=0; the assumption of homogeneity is justified if the t’CAI cluster within errors around t*CAI. This statistical approach is similar to, but improves on, that of[9]. We find t*CAI= 4568.73 ± 0.16 Myr. Below we discuss our methodology and the implications of this age for CAIs, 1.4 Myr older than the reported and typically used age 4567.30±0.16 Myr. Methods: We base our estimate of t*CAIon five achondrites for which published (26Al/27Al)0and Pb-Pb ages exist: the quenched angrites D’Orbigny, Sahara 99555 (SAH 99555), and Northwest Africa (NWA) 1670; the pseudo-eucrite Asuka 881394; and the inner disk achondrite. All are “NC” (non-carbonaceous) achondrites that likely cooled quickly enough that the Al-Mg and Pb-Pb systems achieved isotopic closure simultaneously. We also considered the “CC” (carbonaceous chondrite-like) achondrites NWA 2796 and NWA 6704, butdo not include them in our fit. Al-Mg and Pb-Pb seem not to have closed simultaneously, possibly because formation in the outer disk from volatile-rich composition led to slower cooling. Of the 8 chondrules from NWA 5697 measured by [20,21], we also consider the 4 for which 238U/235U was measured: 2-C1, 5-C2, 3-C5, 11-C1.Depending on their post-formation thermal histories, the Al-Mg and Pb-Pb systems in chondrules may or may not have closed simultaneously. Table 1: (26Al/27Al)0, Pb-Pb ages of selected samplesSample(26Al/27Al)0/ 10-6RefPb-PbRefD’Orbigny3.98±0.15104563.43±0.19♮10-12SAH 995553.64±0.18104563.88±0.2712NWA16705.92±0.59104564.39±0.24*10Asuka 88139413.1±0.5613-154564.98±0.1715NWA 73253.03±0.14164563.4±2.616NWA 27963.94±0.16174562.89±0.5917NWA 67043.03±0.14184562.76±0.26192-C17.56±1.53204567.57±0.56*215-C27.04±1.51204567.54±0.52*213-C58.85±1.83204566.20±0.63*2111-C15.55±1.84204565.84±0.72*21*regression based on one subset of data points ♮weighted mean of two datasets Pb-Pb ages are proportional to the intercept of the line formed by linear regression of 207Pb/206Pb vs. 206Pb/204Pb data from various washes, leachates and residues of acid dissolution of a sample. Because contamination by terrestrial or primordial Pb is pervasive, some fractions must be excluded from regressions to ensure a fit with acceptable mean squares weighted deviation (MSWD). Usually points are excluded based on low [Pb], or low 206Pb/204Pb ratio(low radiogenic component), with single outliers identified [11,12,15,16,17]. In the starred examples (Table 1)and the case of 3 CAI Pb-Pb ages [5], up to half the points were excluded solely because did not fit a pre-determined line. This approach is vulnerable to confirmation bias and produces fits with low MSWD and too-low Pb-Pb age uncertainty. Regressing the same data points as [10], were produce the Pb-Pb age of NWA 1670 of 4564.39±0.24 Myr. But selecting other combinations of data points, other, equally valid, isochrons yield ages from 4563.77±0.21 Myr to 4564.64±0.23 Myr. Similar arguments apply to the Pb-Pb isochrons built by [21] for chondrules 2-C1 (we find 4567.33±0.44 to 4567.85±0.46 Myr), 5-C2 (4566.84±0.53 to 4567.70±0.44 Myr), 3-C5 (4565.84±0.54to 4567.04±0.54)and 11-C1 (4565.36±0.51 to 4565.74±0.45 Myr). Our adopted ages for these and NWA 1670 are listed in Table 2.Table 2. tCAI estimated from various components, using our regressions for the chondrules & NWA 1670.SampleΔt26(Myr)tPb(Myr)t’CAI(Myr)D’Orbigny5.05±0.044563.43±0.194568.48±0.19SAH 995555.14±0.054563.88±0.274569.02±0.27NWA16704.64±0.104564.21±0.634568.85±0.67Asuka 8813943.81±0.044564.98±0.174568.79±0.17NWA 73255.33±0.054563.4±2.64568.7±2.6NWA 27965.06±0.044562.89±0.594567.95±0.59NWA 67045.29±0.134562.76±0.264568.05±0.292-C12.00±0.214567.59±0.704569.59±0.725-C22.07±0.224567.23±0.914569.30±0.933-C51.84±0.214566.44±1.124568.28±1.1411-C12.32±0.344565.52±0.664567.84±0.73achondrite4568.72±0.16chondrules4568.76±0.58combined4568.73±0.16A weighted average of the five NC achondrites(or just D’Orbigny, SAH 99555 and Asuka 881394)yields t*CAI= 4568.72 ± 0.16Myr. All are consistent with this value to within 1.8σ, and MSWD=1.5. Including the 4 U-corrected chondrules, t*CAI= 4568.73± 0.16Myrwith MSWD=1.66, which is statistically significant. All chondrules and NC achondrites are consistent with this to within 1.8σ, (Figure 1).Figure 1. Al-Mg formation times after t=0 vs. Pb-Pb ages. The five NC achondrites and four chondrules are consistent with a Pb-Pb age of t=0 of 4568.7 Myr. Discussion: The data from achondrites and chondrules are consistent with a single Pb-Pb age at t=0, justifying the assumption of 26Al homogeneity. The age, 4568.7 Myr, is ≈1.4 Myr older than the commonly accepted Pb-Pb age of CAIs that formed with canonical 26Al/27Al at t=0 [3]. Others have interpreted the discrepancy to signify 26Al heterogeneity in the CAI-forming region[5,21]. We suggest instead that CAIs were exposed to transient heating events that reset the Pb-Pb system without disturbing the Al-Mg system. Notably, chondrules typically experienced transient heating at these times in the nebula [22]. If so, direct measurements of CAIs will not yield as reliable a Pb-Pb age of t=0 as statistical approaches like this and that of [9].References:[1] Auer et al. 2009. [2] Jacobsen, B et al. 2008, EPSL 272, 353-364. [3] Tissot, Fet al. 2017, GCA 213, 593-617.[4] Villa, I et al. 2016, GCA 172, 387-392.[5] Amelin, Y et al. 2010, EPSL 300, 343-350.[6] Connelly, Jet al. 2012, Science 338, 651.[7] Bouvier, Aet al. 2011, LPICo 1639, 9054. [8] Bouvier, Aand Wadhwa, M2010, Nat Geosci 3, 637-641.[9] Nyquist, Let al. 2009, GCA 73, 5115-5136.[10] Schiller et al. 2015. [11] Wadhwa & Brennecka 2012. [12] Tissot et al. 2017. [13] Nyquist et al. 2003. [14] Wadhwa et al. 2009. [15] Wimpenny et al. 2019, GCA 244, 478-501.[16] Koefoed et al. 2016, GCA 183, 31-45. [17] Bouvier, A et al. 2011, GCA 75, 5310-5323. [18] Sanborn, Met al. 2019, GCA 245, 577-596. [19] Amelin, Yet al. 2019, GCA 245, 628-642.[20] Bollard, Jet al. 2017, Sci Adv 3 ,e1700407. [21] Bollard, Jet al. 2019, GCA 260, 62-83.[22] Villeneuve, J et al. 2009, Science 325, 985

S. J. Desch↗

NASA NTRS1999

Is skeletal muscle ready for long-term spaceflight and return to gravity?

It is now clear that prevention of muscle debilitation during spaceflight will require a broader approach than simple exercise aimed at strengthening of the muscle fibers. The levels of several hormones and receptors are altered by unloading and must be returned to homeostasis. Pharmacotherapy and gene transfer strategies to raise the relative level of structural proteins may minimize the problems faced by astronauts in readapting to Earth-gravity. Up to now, we have only minimally exploited microgravity for advancing our understanding of muscle biology. A research laboratory in the space station with a centrifuge facility (gravity control) is essential for conducting basic research in this field. Microgravity has proven an excellent tool for noninvasively perturbing the synthesis of muscle proteins in the search for molecular signals and gene regulatory factors influencing differentiation, growth, maintenance and atrophy of muscle. Understanding the relation between blood flow and interstitial edema and between workload and subsequent structural failure are but two important problems that require serious attention. The roles of hormones and growth factors in regulating gene expression and their microgravity-induced altered production are other urgent issues to pursue. These types of studies will yield information that advances basic knowledge of muscle biology and offers insights into countermeasure design. This knowledge is likely to assist rehabilitation of diseased or injured muscles in humans on Earth, especially individuals in the more vulnerable aging population and persons participating in strenuous sports. Will the skeletal muscle system be prepared for the increased exposure to microgravity and the return to gravity loading without injury when space station is operational? The answer depends in large part on continued access to space and funding of ground-based models and flight experiments. The previous two decades of spaceflight research have described the effects of microgravity on multiple systems. The next generation of experiments promises to be even more exciting as we are challenged to define the cellular and molecular mechanisms of microgravity-induced changes.

manned↗

NASA NTRS2001

A microwave-powered sterilizable interface for aseptic access to bioreactors that are vulnerable to microbial contamination

Novel methods and apparatus that employ the rapid heating characteristics of microwave irradiation to facilitate the aseptic transfer of nutrients, products, and other materials between microbially sensitive systems and the external environment are described. The microwave-sterilizable access port (MSAP) consists of a 600-W magnetron emitting at a frequency of 2.45 GHz, a sterilization chamber with inlet and outlet flow lines, and a specimen transfer interface. Energy is routed to the sterilization chamber via a coaxial transmission line where small quantities of water couple strongly with the incident radiation to produce a superheated vapor phase. The efficiency of energy transfer is enhanced through the use of microwave susceptors within the sterilization chamber. Mating surfaces are thermally sterilized through direct contact with the hot gas. Efficacy has been demonstrated using the thermophile Bacillus stearothermophilus.

Validation Studies↗

NASA NTRS2007

Fabrication of Buried Nanochannels From Nanowire Patterns

A method of fabricating channels having widths of tens of nanometers in silicon substrates and burying the channels under overlying layers of dielectric materials has been demonstrated. With further refinement, the method might be useful for fabricating nanochannels for manipulation and analysis of large biomolecules at single-molecule resolution. Unlike in prior methods, burying the channels does not involve bonding of flat wafers to the silicon substrates to cover exposed channels in the substrates. Instead, the formation and burying of the channels are accomplished in a more sophisticated process that is less vulnerable to defects in the substrates and less likely to result in clogging of, or leakage from, the channels. In this method, the first step is to establish the channel pattern by forming an array of sacrificial metal nanowires on an SiO2-on-Si substrate. In particular, the wire pattern is made by use of focused-ion-beam (FIB) lithography and a subsequent metallization/lift-off process. The pattern of metal nanowires is then transferred onto the SiO2 layer by reactive-ion etching, which yields sacrificial SiO2 nanowires covered by metal. After removal of the metal covering the SiO2 nanowires, what remains are SiO2 nanowires on an Si substrate. Plasma-enhanced chemical vapor deposition (PECVD) is used to form a layer of a dielectric material over the Si substrate and over the SiO2 wires on the surface of the substrate. FIB milling is then performed to form trenches at both ends of each SiO2 wire. The trenches serve as openings for the entry of chemicals that etch SiO2 much faster than they etch Si. Provided that the nanowires are not so long that the diffusion of the etching chemicals is blocked, the sacrificial SiO2 nanowires become etched out from between the dielectric material and the Si substrate, leaving buried channels. At the time of reporting the information for this article, channels 3 m long, 20 nm deep, and 80 nm wide (see figure) had been fabricated by this method.

Choi, Daniel↗

NASA NTRS2013

A Global Assessment of Long-Term Greening and Browning Trends in Pasture Lands Using the GIMMS LAI3g Dataset

Pasture ecosystems may be particularly vulnerable to land degradation due to the high risk of human disturbance (e.g., overgrazing, burning, etc.), especially when compared with natural ecosystems (non-pasture, non-cultivated) where direct human impacts are minimal. Using maximum annual leaf area index (LAImax) as a proxy for standing biomass and peak annual aboveground productivity, we analyze greening and browning trends in pasture areas from 1982-2008. Inter-annual variability in pasture productivity is strongly controlled by precipitation (positive correlation) and, to a lesser extent, temperature (negative correlation). Linear temporal trends are significant in 23% of pasture cells, with the vast majority of these areas showing positive LAImax trends. Spatially extensive productivity declines are only found in a few regions, most notably central Asia, southwest North America, and southeast Australia. Statistically removing the influence of precipitation reduces LAImax trends by only 13%, suggesting that precipitation trends are only a minor contributor to long-term greening and browning of pasture lands. No significant global relationship was found between LAImax and pasture intensity, although the magnitude of trends did vary between cells classified as natural versus pasture. In the tropics and Southern Hemisphere, the median rate of greening in pasture cells is significantly higher than for cells dominated by natural vegetation. In the Northern Hemisphere extra-tropics, conversely, greening of natural areas is 2-4 times the magnitude of greening in pasture areas. This analysis presents one of the first global assessments of greening and browning trends in global pasture lands, including a comparison with vegetation trends in regions dominated by natural ecosystems. Our results suggest that degradation of pasture lands is not a globally widespread phenomenon and, consistent with much of the terrestrial biosphere, there have been widespread increases in pasture productivity over the last 30 years.

ecosystems↗

NASA NTRS2016

Experiences with Extra-Vehicular Activities in Response to Critical ISS Contingencies

The maturation of the International Space Station (ISS) design from the proposed Space Station Freedom to today's current implementation resulted in external hardware redundancy vulnerabilities in the final design. Failure to compensate for or respond to these vulnerabilities could put the ISS in a posture to where it could no longer function as a habitable space station. In the first years of ISS assembly, these responses were to largely be addressed by the continued resupply and Extra-Vehicular Activity (EVA) capabilities of the Space Shuttle. Even prior to the decision to retire the Space Shuttle, it was realized that ISS needed to have its own capability to be able to rapidly repair or replace external hardware without needing to wait for the next cargo resupply mission. As documented in a previous publicatoin5, in 2006 development was started to baseline Extra- Vehicular Activity (EVA, or spacewalk) procedures to replace hardware components whose failure would expose some of the ISS vulnerabilities should a second failure occur. This development work laid the groundwork for the onboard crews and the ground operations and engineering teams to be ready to replace any of this failed hardware. In 2010, this development work was put to the test when one of these pieces of hardware failed. This paper will provide a brief summary of the planning and processes established in the original Contingency EVA development phase. It will then review how those plans and processes were implemented in 2010, highlighting what went well as well as where there were deficiencies between theory and reality. This paper will show that the original approach and analyses, though sound, were not as thorough as they should have been in the realm of planning for next worse failures, for documenting Programmatic approval of key assumptions, and not pursuing sufficient engineering analysis prior to the failure of the hardware. The paper will further highlight the changes made to the Contingency EVA preparation team structure, approach, goals, and the resources allocated to its work after the 2010 events. Finally, the authors will overview the implementation of these updates in addressing failures onboard the ISS in 2012, 2013, and 2014. The successful use of the updated approaches, and the application of the approaches to other spacewalks, will demonstrate the effectiveness of this additional work and make a case for putting significant time and resources into pre-failure planning and analysis for critical hardware items on human-tended spacecraft.

Van Cise, E. A.↗

NASA NTRS2016

Experiences with Extra-Vehicular Activities in Response to Critical ISS Contingencies

The maturation of the International Space Station (ISS) design from the proposed Space Station Freedom to today's current implementation resulted in external hardware redundancy vulnerabilities in the final design. Failure to compensate for or respond to these vulnerabilities could put the ISS in a posture where it could no longer function as a habitable space station. In the first years of ISS assembly, these responses were to largely be addressed by the continued resupply and Extra-Vehicular Activity (EVA) capabilities of the Space Shuttle. Even prior to the decision to retire the Space Shuttle, it was realized that ISS needed to have its own capability to be able to rapidly repair or replace external hardware without needing to wait for the next cargo resupply mission. As documented in a previous publication, in 2006 development was started to baseline Extra-Vehicular Activity (EVA, or spacewalk) procedures to replace hardware components whose failure would expose some of the ISS vulnerabilities should a second failure occur. This development work laid the groundwork for the onboard crews and the ground operations and engineering teams to be ready to replace any of this failed hardware. In 2010, this development work was put to the test when one of these pieces of hardware failed. This paper will provide a brief summary of the planning and processes established in the original Contingency EVA development phase. It will then review how those plans and processes were implemented in 2010, highlighting what went well as well as where there were deficiencies between theory and reality. This paper will show that the original approach and analyses, though sound, were not as thorough as they should have been in the realm of planning for next worse failures, for documenting Programmatic approval of key assumptions, and not pursuing sufficient engineering analysis prior to the failure of the hardware. The paper will further highlight the changes made to the Contingency EVA preparation team structure, approach, goals, and the resources allocated to its work after the 2010 events. Finally, the authors will overview the implementation of these updates in addressing failures onboard the ISS in 2012, 2013, and 2014. The successful use of the updated approaches, and the application of the approaches to other spacewalks, will demonstrate the effectiveness of this additional work and make a case for putting significant time and resources into pre-failure planning and analysis for critical hardware items on human-tended spacecraft.

Van Cise, E. A.↗

NASA NTRS2016

Building Climate Resilience at NASA Ames

NASA Ames Research Center, located at the southern end of the San Francisco Bay (SFB) estuary has identified three primary vulnerabilities to changes in climate. The Ames Climate Adaptation Science Investigator (CASI) workgroup has studied each of these challenges to operations and the potential exposure of infrastructure and employees to an increased frequency of hazards. Sea level rise inundation scenarios for the SFB Area generally refer to projected scenarios in mean sea level rather than changes in extreme tides that could occur during future storm conditions. In the Summer of 2014, high resolution 3-D mapping of the low lying portion of Ames was performed. Those data are integrated with improved sea level inundation scenarios to identify the buildings, basements and drainage systems potentially affected. We will also identify the impacts of sea level and storm surge effects on transportation to and from the Center. This information will help Center Management develop future Master Plans. Climate change will also lead to changes in temperature, storm frequency and intensity. These changes have potential impacts on localized floods and ecosystems, as well as on electricity and water availability. Over the coming decades, these changes are going to be imposed on top of ongoing land use and land cover changes, especially those deriving from continued urbanization and increase in impervious surface areas. These coupled changes have the potential to create a series of cascading impacts on ecosystems, including changes in primary productivity and disturbance of hydrological properties and increased flood risk.The majority of the electricity used at Ames is supplied by hydroelectric dams, which will be influenced by reductions in precipitation or changes in the timing or phase of precipitation which reduces snow pack. Coupled with increased demand for summertime air conditioning and other cooling needs, NASA Ames is at risk for electricity shortfalls. To assess the anticipated energy usage as climate changes, the Ames CASI team is collecting historical energy usage data from Ames facilities, historical weather data, and projected future weather parameters from the CASI Climate subgroup. This data will be incorporated into the RETScreen model to predict how energy usage at Ames will change over the coming century.

climate↗