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A technique is described for breaking ice in the path of a ship. A laser is placed on the bow of the ship with apparatus to scan the ice in the path of the ship with the laser beam. The beam cuts or shatters the ice, enabling the ship to break the ice in its path.
The losses which are experienced after a break or stoppage in sequence of a production cycle portends an extremely complex situation and involves numerous variables, some of uncertain quantity and quality. There are no discrete formulas to define the losses during a gap in production. The techniques which are employed are therefore related to a prediction or forecast of the losses that take place, based on the conditions which exist in the production environment. Such parameters as learning curve slope, number of predecessor units, and length of time the production sequence is halted are utilized in formulating a prediction model. The pertinent current publications related to this subject are few in number, but are reviewed to provide an understanding of the problem. Example problems are illustrated together with appropriate trend curves to show the approach. Solved problems are also given to show the application of the models to actual cases or production breaks in the real world.
The size of oceanic air bubbles produced by whitecaps and wave-breaking is determined. The production of liquid aerosols at the sea surface is predicted. These liquid aerosols are at the origin of most of the particulate materials exchanged between the ocean and the atmosphere. A prototype was designed and built using an optical technique based on the principle of light scattering at an angle of ninety degrees from the incident light beam. The output voltage is a direct function of the bubble diameter. Calibration of the probe was carried out within a range of 300 microns to 1.2 mm. Bubbles produced by wave-breaking in a large air-sea interaction simulating facility. Experimental results are given in the form of size spectrum.
Scale breaking model and gammaisation processes for high energies give a correct description of the longitudinal development of extensive air showers (E.A.S.). From the analysis of phenomenological characteristics of E.A.S. at Tien-Shan experiment, it follows that for energies near 10 to the 6 GeV the secondary particle multiplicity increases with energy faster than is predicted by the accepted scale breaking model.
The steady state gravity wave model of Schoeberl et al. (1983) is extended to compute wave breaking by disturbances originating at the earth's surface. For winter and summer mean zonal wind profiles, no waves reach the mesosphere unless the absolute value of the zonally averaged perturbed zonal velocity minus c is greater than approximately 20 m/sec. Gravity waves with c = 0 can only reach the winter mesosphere if planetary scale waves are present in the troposphere and the lower stratosphere, to provide strong zonal wind channels for upward wave propagation. This results in nonzonal wave breaking in the mesosphere which could provide in situ forcing of planetary waves. Dissipation of gravity waves by molecular viscosity and conduction can provide significant deceleration and heating/cooling in the 85-105 km region.
The influence of breaking gravity waves on the dynamics and chemical composition of the 60 to 110 km region is investigated with a two dimensional model that includes a parameterization of gravity wave momentum deposition and diffusion. The dynamical model is described by Garcia and Solomon (1983) and Solomon and Garcia (1983) and includes a complete chemical scheme for the mesosphere and lower thermosphere. The parameterization of Lindzen (1981) is used to calculate the momentum deposited and the turbulent diffusion produced by the gravity waves. It is found that wave momentum deposition drives a very vigorous mean meridional circulation, produces a very cold summer mesopause and reverse the zonal wind jets above about 85 km. The seasonal variation of the turbulent diffusion coefficient is consistent with the behavior of mesospheric turbulences inferred from MST radar echoes. The large degree of consistency between model results and various types of dynamical and chemical data supports very strongly the hypothesis that breaking gravity waves play a major role in determining the zonally-averaged dynamical and chemical structure of the 60 to 110 km region of the atmosphere.
The cosmological consequences of spontaneous breaking of an approximate discrete symmetry are studied. The breaking leads to formation of proto-domains of false and true vacuum separated by domain walls of thickness determined by the mass scale of the model. The cosmological evolution of the walls is extremely sensitive to the magnitude of the biasing; several scenarios are possible, depending on the interplay between the surface tension on the walls and the volume pressure from the biasing. Walls may disappear almost immediately after they form, or may live long enough to dominate the energy density of the Universe and cause power-law inflation. Limits are obtained on the biasing that characterizes each possible scenario.
An effective theory of superconductivity based on a microscopic theory of the T- and P-breaking spin-liquid state is proposed. There are two independent gauge invariances broken by two separate condensates. The theory may be useful for phenomenological calculations. In particular, it is found that the H(c1) are different for magnetic fields with opposite orientations. It is also found that the polarization of an electromagnetic wave is rotated after reflection from these T- and P-breaking superconductors.
DNA double strand breaks (DSB's) are the critical lesions involved in cellular effects of ionizing radiation. Therefore, the evaluation of DSB induction in mammalian cells after heavy ion irradiation is an essential task for the assessment of high-LET radiation risk in space. Of particular interest has been the question of how the biological efficiency for the cellular inactivation endpoint relates to the initial lesions (DSBs) at varying LETs. For cell killing, an increased Relative Biological Efficiency (RBE) has been determined for highLET radiation around 100-200 keV/mu m. At higher LET, the RBE's decrease again to values below one for the very heavy particles. At GSI, DSB-induction was measured in CHO-K1 cells following irradiation with accelerated particles covering a wide LET range. The electrophoretic elution of fragmented DNA out of agarose plugs in a constant electrical field was applied for the detection of DSB's. The fraction of DNA retained was determined considering the relative intensities of ethidium bromide fluorescence in the well and in the gel lane. Dose-effect curves were established, from which the RBE for DSB induction was calculated at a fraction of 0.7 of DNA retained In summary, these rejoining studies are in line with an enhanced severity of the DNA DSB's at higher LET's, resulting in a decreased repairability of the induced lesions. However, no information concerning the fidelity of strand breaks rejoining is provided in these studies. To assess correct rejoining of DNA fragments an experimental system involving individual DNA hybridization bands has been set up. In preliminary experiments Sal I generated DNA fragments of 0.9 Mbp were irradiated with xrays and incubated for repair However, restitution of the original signals was not observed, probably due to the high radiation dose necessary for breakage of a fragment of this size. A banding pattern with NotI hybridization signals in a higher MW range (3Mbp) has been obtained by varying the electrophoretic conditions and correct rejoining studies will be further developed in this system.
Many problems in geophysical and astrophysical convection systems are characterized by fast rotation and spherical shell geometry. The combined effects of Coriolis forces and spherical shell geometry produce a unique spatial symmetry for the convection pattern in a rapidly rotating spherical shell. In this paper, we first discuss the general spatial symmetries for rotating spherical shell convection. A special model, a spherical shell heated from below, is then used to illustrate how and when the spatial symmetries are broken. Symmetry breaking occurs via a sequence of spatial transitions from the primary conducting state to the complex multiple-layered columnar structure. It is argued that, because of the dominant effects of rotation, the sequence of spatial transitions identified from this particular model is likely to be generally valid. Applications of the spatial symmetry breaking to planetary convection problems are also discussed.
The effects of mechanical stirring on nucleation and chiral symmetry breaking have been investigated for a simple inorganic molecule, sodium chlorate (NaClO3). In contrast to earlier findings, our experiment suggests that the symmetry breaking may have little to do with hydrodynamic convection. Rather the effect can be reasonably accounted for by mechanical damage to incipient crystals. The catastrophic events, creating numerous small 'secondary' crystals, produce statistical domination of one chiral species over the other. Our conclusion is supported by a number of observations using different mixing mechanisms.
Since 1961, almost 160 satellite break-ups have occurred on-orbit, and have been the major contributor to the growth of the orbital debris population. When a satellite breaks up, the debris exists in a relatively concentrated form, orbiting in a loose cloud with the parent body until orbital perturbations disperse the cloud into the average background. Manned space activities, which usually take place in low Earth orbit at altitudes less than 500 km, have been continuous for the past I I years while Mir was inhabited and promise to be again continuous when the International Space Station becomes permanently manned. This paper surveys historical breakups over the last I I years to determine the number that affect altitudes lower than 500 km. Selected breakup are analyzed using NASA's Satellite Breakup Risk Assessment Model (SBRAM) to determine the specific short term risk from those breakups to manned missions.
The yield of DNA double-strand breaks (DSBs) in SV40 DNA irradiated in aqueous solution was found to increase by more than a factor of two as a result of postirradiation incubation of the DNA at 50 degrees C and pH 8.0 for 24 h. This is in agreement with data from studies performed at 37 degrees C that were published previously. Importantly, similar results were also obtained from irradiation of mammalian DNA in agarose plugs. These results suggest that heat-labile sites within locally multiply damaged sites are produced by radiation and are subsequently transformed into DSBs. Since incubation at 50 degrees C is typically employed for lysis of cells in commonly used pulsed-field gel assays for detection of DSBs in mammalian cells, the possibility that heat-labile sites are present in irradiated cells was also studied. An increase in the apparent number of DSBs as a function of lysis time at 50 degrees C was found with kinetics that was similar to that for irradiated DNA, although the magnitude of the increase was smaller. This suggests that heat-labile sites are also formed in the cell. If this is the case, a proportion of DSBs measured by the pulsed-field gel assays may occur during the lysis step and may not be present in the cell as breaks but as heat-labile sites. It is suggested that such sites consist mainly of heat-labile sugar lesions within locally multiply damaged sites. Comparing rejoining of DSBs measured with short and long lysis procedure indicates that the heat-labile sites are repaired with fast kinetics in comparison with repair of the bulk of DSBs.
Induction of DNA double-strand breaks (dsbs) in mammalian cells is dependent on the spatial distribution of energy deposition from the ionizing radiation. For high LET particle radiations the primary ionization sites occur in a correlated manner along the track of the particles, while for X-rays these sites are much more randomly distributed throughout the volume of the cell. It can therefore be expected that the distribution of dsbs linearly along the DNA molecule also varies with the type of radiation and the ionization density. Using pulsed-field gel and conventional gel techniques, we measured the size distribution of DNA molecules from irradiated human fibroblasts in the total range of 0.1 kbp-10 Mbp for X-rays and high LET particles (N ions, 97 keV/microns and Fe ions, 150 keV/microns). On a mega base pair scale we applied conventional pulsed-field gel electrophoresis techniques such as measurement of the fraction of DNA released from the well (FAR) and measurement of breakage within a specific NotI restriction fragment (hybridization assay). The induction rate for widely spaced breaks was found to decrease with LET. However, when the entire distribution of radiation-induced fragments was analysed, we detected an excess of fragments with sizes below about 200 kbp for the particles compared with X-irradiation. X-rays are thus more effective than high LET radiations in producing large DNA fragments but less effective in the production of smaller fragments. We determined the total induction rate of dsbs for the three radiations based on a quantitative analysis of all the measured radiation-induced fragments and found that the high LET particles were more efficient than X-rays at inducing dsbs, indicating an increasing total efficiency with LET. Conventional assays that are based only on the measurement of large fragments are therefore misleading when determining total dsb induction rates of high LET particles. The possible biological significance of this non-randomness for dsb induction is discussed.
A biophysical model for the kinetics of the formation of radiation-induced chromosome aberrations is developed to account for the recent experimental results obtained with a combination of the premature chromosome condensation (PCC) and fluorescence in situ hybridization (FISH) techniques. In this model, we consider the broken ends of DNA double-strand breaks (DSBs) to be reactant and make use of the interaction distance hypothesis. The repair/misrepair process between broken ends is suggested to consist of two steps; the first step represents the two break ends approaching each other, and the second step represents the enzymatic processes leading to DNA end-to-end rejoining. Only the second step is reflected in the kinetics observed in experiments using PCC. The model appears to be able to fit existing data for human cells. It is shown that the kinetics of the formation of chromosome aberrations can be explained by a single rate that characterizes both rejoining and misrejoining of DSBs, suggesting that repair and misrepair share the same mechanism. Fast repair (completed in minutes) in a subset of DSBs is suggested as an explanation of the complete exchanges observed with PCC in human lymphocytes immediately after irradiation. The fast repair component seems to be absent in human fibroblasts.
An assay that allows measurement of absolute induction frequencies for DNA double-strand breaks (dsbs) in defined regions of the genome and that quantitates rejoining of correct DNA ends has been used to study repair of dsbs in normal human fibroblasts after x-irradiation. The approach involves hybridization of single-copy DNA probes to Not I restriction fragments separated according to size by pulsed-field gel electrophoresis. Induction of dsbs is quantitated from the decrease in the intensity of the hybridizing restriction fragment and an accumulation of a smear below the band. Rejoining of dsbs results in reconstitution of the intact restriction fragment only if correct DNA ends are joined. By comparing results from this technique with results from a conventional electrophoresis assay that detects all rejoining events, it is possible to quantitate the misrejoining frequency. Three Not I fragments on the long arm of chromosome 21 were investigated with regard to dsb induction, yielding an identical induction rate of 5.8 X 10(-3) break per megabase pair per Gy. Correct dsb rejoining was measured for two of these Not I fragments after initial doses of 80 and 160 Gy. The misrejoining frequency was about 25% for both fragments and was independent of dose. This result appears to be representative for the whole genome as shown by analysis of the entire Not I fragment distribution. The correct rejoining events primarily occurred within the first 2 h, while the misrejoining kinetics included a much slower component, with about half of the events occurring between 2 and 24 h. These misrejoining kinetics are similar to those previously reported for production of exchange aberrations in interphase chromosomes.
Not enough is known about the increased risk of hypobaric decompression sickness (DCS) and production of venous (VGE) and arterial (AGE) gas emboli following an air break in an otherwise normal 100% resting oxygen (O2) prebreathe (PB), and certainly a break in PB when exercise is used to accelerate nitrogen (N2) elimination from the tissues. Current Aeromedical Flight Rules at the Johnson Space Center about additional PB payback times are untested, possibly too conservative, and therefore not optimized for operational use.
The intentional break-up of the Fengyun-1C spacecraft on 11 January 2007 via hypervelocity collision with a ballistic object created the most severe artificial debris cloud in Earth orbit since the beginning of space exploration. More than 900 debris on the order of 10 cm or greater in size have been identified by the U.S. Space Surveillance Network (SSN). The majority of these debris reside in long-lived orbits. The NASA Orbital Debris Program Office has conducted a thorough examination of the nature of the Fengyun-1C debris cloud, using SSN data for larger debris and special Haystack radar observations for smaller debris. These data have been compared with the NASA standard satellite break-up model for collisions, and the results are presented in this paper. The orbital longevity of the debris have also been evaluated for both small and large debris. The consequent long-term spatial density effects on the low Earth orbit (LEO) regime are then described. Finally, collision probabilities between the Fengyun-1C debris cloud and the resident space object population of 1 January 2007 have been calculated. The potential effect on the growth of the near-Earth satellite population is presented.