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At least 217 records · Page 12

The physiology and biochemistry of total body immobilization in animals: A compendium of research

Major studies that describe the physiological and biochemical mechanisms which operate during total body restraint (confinement in cages for example) are presented. The metabolism and behavior of various animals used in medical research (dogs, monkeys, rats, fowl) was investigated and wherever possible a detailed annotation for each study is provided under the subheadings: (a) purposes, (b) procedures and methods, (c) results, and (d) conclusions. Selected references are also included.

Dorchak, K. J.↗

FORTRAN program for induction motor analysis

A FORTRAN program for induction motor analysis is described. The analysis includes calculations of torque-speed characteristics, efficiency, losses, magnetic flux densities, weights, and various electrical parameters. The program is limited to three-phase Y-connected, squirrel-cage motors. Detailed instructions for using the program are given. The analysis equations are documented, and the sources of the equations are referenced. The appendixes include a FORTRAN symbol list, a complete explanation of input requirements, and a list of error messages.

Bollenbacher, G.↗

Animal exposure during burn tests

An animal exposure test system has been designed and fabricated for the purpose of collecting physiological and environmental (temperature) data from animal subjects exposed to combustion gases in large scale fire tests. The AETS consists of an open wire mesh, two-compartment cage, one containing an exercise wheel for small rodents, and the other containing one rat instrumented externally for electrocardiogram and respiration. The ECG and respiration sensors are located in a belt placed around the torso of the subject, electrode wires forming an umbilical to a connector in the top of the compartment. A cable extends from the connector to the power supply and signal conditioning electronics. These are connected to a dual-beam oscilloscope for real time monitoring and a magnetic tape recorder having three or more channels. Endpoints observed are bradycardia, cardiac arrhythmias, changes in respiratory pattern, respiratory arrest and cardiac arrest. The ECG record also appears to be a good method of monitoring animal activity as indicated by an increase in EMG noise superimposed on the record during increased activity of the torso musculature. Examples of the recordings are presented and discussed as to their significance regarding toxicity of fire gases.

Gaume, J. G.↗

Microelectronic bioinstrumentation systems

Progress was made in the development of an RF cage, a single channel RF powered ECG telemetry system, and a three channel RF powered ECG, aortic blood pressure, and body temperature telemetry system. Encapsulation materials for chronic implantation of electronic circuits in the body were also evaluated.

Ko, W. H.↗

Increased rate of response of the pituitary-adrenal system in rats adapted to chronic stress

The response and adaptation of the pituitary-adrenal system to chronic stresses was investigated. These included individual caging, confinement, and exposure to cold for varying periods of time. Studies were carried out demonstrating that during the period of adaptation when plasma corticosterone concentrations returned toward their prestress level despite continued exposure to the stressor, the animals responded to additional stimuli of ether for 1 min, a saline injection, or release from confinement with a faster increase (within 2.5 min) in plasma corticosterone than controls (10 min). It is concluded that during adaptation to a chronic stress the pituitary-adrenal system is not inhibited by the circulating steroid level but is actually hypersensitive to additional stimuli.

Sakellaris, P. C.↗

A perceptual channel for information transfer over kilometer distances Historical perspective and recent research

For more than 100 years, scientists have attempted to determine the truth or falsity of claims for the existence of a perceptual channel whereby certain individuals are able to perceive and describe remote data not presented to any known sense. This paper presents an outline of the history of scientific inquiry into such so-called paranormal perception and surveys the current state of the art in parapsychological research in the United States and abroad. The nature of this perceptual channel is examined in a series of experiments carried out in the Electronics and Bioengineering Laboratory of Stanford Research Institute. The perceptual modality most extensively investigated is the ability of both experienced subjects and inexperienced volunteers to view, by innate mental processes, remote geographical or technical targets including buildings, roads, and laboratory apparatus. The accumulated data indicate that the phenomenon is not a sensitive function of distance, and Faraday cage shielding does not in any apparent way degrade the quality and accuracy of perception. On the basis of this research, some areas of physics are suggested from which a description or explanation of the phenomenon could be forthcoming.

Puthoff, H. E.↗

Dual-purpose laboratory cage/antenna

Part of steel cage enclosing laboratory animals is used as an antenna to transmit biotelemetry over short distances. Receiving and signal processing equipment are located above ground potential to avoid transmission-path difficulties.

Lalande, B. H.↗

Dynamics of roller bearings considering elastohydrodynamic forces

The life and load carrying capacity of roller bearing are highly influenced by the sliding velocities at the contacts between rollers and races. In this investigation, a computational model was developed to predict traction forces, forces on the cage, sliding and spinning speeds of the roller when the bearing is lubricated with a fluid of known traction coefficient characteristics as functions of pressure and velocities.

Molina, M. A.↗

Common approach to solving SGEMP, DEMP, and ESD survivability

System Generated Electromagnetic Pulse (SGEMP) and Dispersed Electromagnetic Pulse DEMP) are nuclear generated spacecraft environments. Electrostatic discharge (ESD) is a natural spacecraft environment resulting from differential charging in magnetic substorms. All three phenomena, though differing in origin, result in the same problem to the spacecraft and that is Electromagnetic Interference (EMI). A common design approach utilizing a spacecraft structural Faraday Cage is presented which helps solve the EMI problem. Also, other system design techniques are discussed which minimize the magnitude of these environments through control of materials and electrical grounding configuration.

Ling, D.↗

Wear-resistant ball bearings for space applications

Ball bearings consisting of steel parts of which the rings are coated with hard, wear resistant, chemical vapor deposited TiC are described. Experiments conducted in ultrahigh vacuum, using cages of various materials with self-lubricating properties, show that such bearings are suitable for space applications. The results of laboratory tests on the ESA Meteosat Radiometer Focalizing mechanism, which contains six coated bearings, are summarized.

Boving, H.↗

Compact electron-beam source for formation of neutral beams of very low vapor pressure materials

In order to form metal vapors for neutral beam studies, an electron-beam heater and a power supply have been designed. The source, which measures about 30 x 50 x 70 mm, consists of a filament, accelerating plate (defined by pole pieces), and a supported target. The electrons from the filament are focused by the field penetration through a 2 mm slit in the high-voltage cage. They are then accelerated to about 5 kV to a ground plate. The electrons then follow a path in the magnetic field and strike the sample to be heated on its front surface. The assembly is attached to a water-cooled base plate. The electron beam source has produced beams of Ta and C particles with densities of about 10 to the 8th power/cu cm.

Rutherford, J. A.↗

GEOS axial booms

A booms and mechanisms subsystem was designed, developed, and qualified for the geostationary scientific satellite GEOS. Part of this subsystem consist of four axial booms consisting of one pair of 1 m booms and one pair of 2.5 m booms. Each of these booms is carrying one bird cage electric field sensor. Alignment accuracy requirements led to a telescopic type solution. Deployment is performed by pressurized nitrogen. At deployment in orbit two of these booms showed some anomalies and one of these two deployed only about 80%. Following this malfunction a detailed failure investigation was performed resulting in a design modification of some critical components as release mechanism, guide sleeves of the telescopic elements, and pressure system.

Schmidt, G. K.↗

Wear-resistant ball bearings for space applications

Ball bearings for hostile environments were developed. They consist of normal ball bearing steel parts of which the rings are coated with hard, wear-resistant, chemical vapor deposited (C.V.D) TiC. Experiments in ultrahigh vacuum, using cages of various materials with self-lubricating properties, have shown that such bearings are suitable for space applications.

Boving, H.↗

Precision controllability of the F-15 airplane

A flying qualities evaluation conducted on a preproduction F-15 airplane permitted an assessment to be made of its precision controllability in the high subsonic and low transonic flight regime over the allowable angle of attack range. Precision controllability, or gunsight tracking, studies were conducted in windup turn maneuvers with the gunsight in the caged pipper mode and depressed 70 mils. This evaluation showed the F-15 airplane to experience severe buffet and mild-to-moderate wing rock at the higher angles of attack. It showed the F-15 airplane radial tracking precision to vary from approximately 6 to 20 mils over the load factor range tested. Tracking in the presence of wing rock essentially doubled the radial tracking error generated at the lower angles of attack. The stability augmentation system affected the tracking precision of the F-15 airplane more than it did that of previous aircraft studied.

Sisk, T. R.↗

In-vivo bone strain telemetry in monkeys /M. nemestrina/

A new method for collecting in-vivo bone strain data in monkeys has been developed and tested. The method includes a system which consists of a new design of implantable strain transducer and its companion telemetry package. The transducer fits into a hole drilled in a monkey tibia and is threaded for subsequent bone ingrowth. The transducers and telemetry package are biocompatible for over 503 days. The telemetry package uses Pulse Interval Ratio Modulation (PIRM) to transmit strain information to receiving equipment located outside the animal housing cage.

Young, D. R.↗

Biological specimen holding facilities for Spacelab experiments

The paper describes the design, development, integration, and testing of two prototype holding facilities: (1) a unit housing 36 laboratory rats in individual cages, and (2) a unit housing one unrestrained 14-kg rhesus monkey. Both units are environmentally controlled enclosures complete with food, water, and waste-collection equipment. Timer-controlled fluorescent lights in both units permit automatic day-night cycling. Both units are designed to be compatible with Spacelab interfaces and to be operated by NASA payload specialists.

Jackson, J. K.↗

Weight control and restraint of laboratory rats

The use of restrained and confined rats in some procedures used in combustion toxicology introduces the problems of obtaining rats of the appropriate size for the apparatus, and of identifying any artifacts resulting from the use of restraint alone. Feeding studies indicate that controlled feeding of fast-growing strains such as the Sprague-Dawley can hold rat size essentially constant for significant periods of time. The undesirable aspects are the need to cage the animals individually, with resultant psychological as well as metabolic effects. Restraint studies of slow-growing strains such as the Fischer 344 indicate that denying access to food and water for periods of several hours at a time interrupts normal gain only temporarily.

Hilado, C. J.↗