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At least 217 records · Page 12

The Short-Baseline Neutrino Program at Fermilab

The Short-Baseline Neutrino (SBN) program consists of three liquid argon time-projection chamber detectors located along the Booster Neutrino Beam at Fermi National Accelerator Laboratory. Its main goals include searches for New Physics—particularly eV-scale sterile neutrinos, detailed studies of neutrino–nucleus interactions at the GeV energy scale, and the advancement of the liquid argon detector technology that will also be used in the DUNE/LBNF long-baseline neutrino experiment in the next decade. Here, we review these science goals and the current experimental status of SBN.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Experimental Considerations in Long-Baseline Neutrino Oscillation Measurements

Long-baseline neutrino oscillation experiments, which are among the largest neutrino experiments in the world, have extensive physics programs to make precision measurements of three-flavor oscillation parameters, search for physics beyond the Standard Model, and study neutrinos from astrophysical sources. In this article, experimental considerations, including oscillation phenomenology, detector and experiment design, and analysis strategies, are described, with a focus on the three-flavor oscillation measurements. Current and future experiments are discussed, and significant sources of systematic uncertainty, along with mitigation strategies, are emphasized as control of systematic uncertainty is critical for success in precise measurement of long-baseline oscillation parameters. This article is structured as a primer for those new to this area of experimental work.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Centipod WEC, Advanced Controls, Baseline LCOE

Project baseline levelized cost of energy (LCOE) model for the Centipod WEC containing annual energy production (AEP) data, a cost breakdown structure (CBS), model documentation, and the LCOE content model. This baseline was built for comparison with the resultant LCOE model, built after implementation of the model predictive control (MPC) controller.

16 TIDAL AND WAVE POWER↗

Adapting the M3 Surveillance Metrics for an Unknown Baseline

The original M 3 surveillance metrics assume that the baseline is known. In this article, adapted M 3 metrics are presented when the baseline is not known and estimated by available data. Deciding on how much available data is enough is also discussed.

97 MATHEMATICS AND COMPUTING↗

Baseline Characterization Database Verification Report - NBG-18 Billet 635-14

The purpose of this Engineering Calculations and Analysis Report is to present the data being collected in the Baseline Graphite Characterization program, which is directly tasked with supporting the Idaho National Laboratory’s (INL’s) research and development efforts on the Next Generation Nuclear Plant (NGNP)/Very High Temperature Reactor (VHTR)/Advanced Reactor Technology (ART). This program is populating a comprehensive database that will reflect the baseline properties of nuclear-grade graphite regarding individual grade, billet, and position within individual billets. The physical and mechanical property information being collected will be transferred to the NGNP Data Management and Analysis System (NDMAS), and from that database will help populate handbook of property data available to member nations of the Generation IV International Forum (GIF).

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

WaterTAP3 Model Results for NAWI's Baseline Analyses

Description: This folder contains the results for the WaterTAP3 model that was used for the eight NAWI (National Alliance for Water Innovation) baseline studies published in the Environmental Science and Technology special issue: Technology Baselines and Innovation Priorities for Water Treatment and Supply. The data structure and content are described in a README.txt file. For more details on how to use the data and interpret the results please refer to the model documentation and GitHub site linked in the submission.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗

International Data Transfer for Space Very Long Baseline Interferometry

Space Very Long Baseline Interferometry (SVLBI) experiments using a TDRSS satellite have successfully demonstrated the capability of using spacecraft to extend the effective baseline length of VLBI observations beyond the diameter of the Earth, thereby improving the resolution for imaging of active galactic nuclei at centimeter wavelengths.

Space↗

Baseline Characterization Database Verification Report - PCEA Billet 02S8-5

The purpose of this engineering calculations and analysis report (ECAR) is to present data collected in the Baseline Graphite Characterization Program, which is directly tasked with supporting the Idaho National Laboratory's (INL's) research and development efforts on the Advanced Reactor Technologies (ART) Program. This program populates a comprehensive database that reflects the baseline properties of nuclear-grade graphite regarding individual grade, billet, and position within individual billets. The physical- and mechanical-property information being collected will be transferred to the Nuclear Data Management and Analysis System (NDMAS), and that database will help populate the handbook of property data available to member nations of the Generation-IV International Forum. Transfer of these data from the applicable technical lead to the dissemination databases available to other end users requires a full review of the test procedures and data-collection efforts through an analysis of the multiple summary spreadsheets and values being collected. This report represents the analysis for PCEA Billet 02S8-5 and facilitates release of associated data to the NDMAS custodians.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Baseline Characterization Database Verification Report - PCEA Billet 01S8-9

The purpose of this engineering calculations and analysis report (ECAR) is to present data collected in the Baseline Graphite Characterization Program, which is directly tasked with supporting the Idaho National Laboratory's (INL's) research and development efforts on the Advanced Reactor Technologies (ART) Program. This program populates a comprehensive database that reflects the baseline properties of nuclear-grade graphite with regard to individual grade, billet, and position within individual billets. The physical- and mechanical-property information being collected will be transferred to the Nuclear Data Management and Analysis System (NDMAS), and that database will help populate the handbook of property data available to member nations of the Generation-IV International Forum. Transfer of these data from the applicable technical lead to the dissemination databases available to other end users requires a full review of the test procedures and data-collection efforts through an analysis of the multiple summary spreadsheets and values being collected. This report represents the analysis for PCEA Billet 01S8-9 and facilitates release of associated data to the NDMAS custodians.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

ECAR: Baseline Characterization Database Verification Report – PCEA Billet 01D3-35

The purpose of this engineering calculations and analysis report (ECAR) is to present data collected in the Baseline Graphite Characterization Program, which is directly tasked with supporting the Idaho National Laboratory’s (INL’s) research and development efforts on the Advanced Reactor Technologies (ART) Program. This program populates a comprehensive database that reflects the baseline properties of nuclear-grade graphite with regard to individual grade, billet, and position within individual billets. The physical- and mechanical-property information collected will be transferred to the Nuclear Data Management and Analysis System (NDMAS), and that database will help populate the handbook of property data available to member nations of the Generation-IV International Forum. Transfer of these data from the applicable technical lead to the dissemination databases available to other end users requires a full review of the test procedures and data-collection efforts through an analysis of the multiple summary spreadsheets and values being collected. This report represents the analysis for PCEA Billet 01D3-35 and facilitates release of associated data to the NDMAS custodians.

11 - NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

FishGen.net: An Online Genetic Repository for Salmon and Steelhead Genetic Baselines

Abstract FishGen is a final repository for Pacific salmon Oncorhynchus spp. and steelhead O. mykiss genetic data generated as part of the genetic stock identification and parentage-based tagging projects in the Columbia River basin and throughout the Pacific Coast of North America. Resource Data, Inc., developed this web-based, GIS-interfaced software, which is freely available to the public, with funding from the Pacific Coastal Salmon Recovery Fund and Bonneville Power Administration. FishGen currently houses genetic stock identification baselines for both Chinook Salmon O. tshawytscha and steelhead in the Columbia and Snake river basins, as well as hatchery, parentage-based, tagging baselines for both species in the Snake River basin. Because it has a user-friendly interface and protocol for submitting and storing standardized genetic and sample metadata, it is an excellent tool for supporting genetic research and monitoring projects throughout the region.

McCane, Jesse↗

Constraining non-standard neutrino interactions with neutral current events at long-baseline oscillation experiments

We explore, for the first time, neutral-curren t events at long-baseline experiments to constrain vector and axial-vector neutrino non-standard interactions (NSI) with quarks. We leverage the flavor dependence of NSIs to perform an oscillation analysis in the neutral- current channel. We first introduce a framework to parametrize the effect of NSI on the cross section. Then, as an example, we analyze NOvA neutral-current data which provides significantly improved constraints on the axial-vector NSI parameters ${\varepsilon}_{\mu \mu}^A$, ${\varepsilon}_{\tau \tau}^A$ and ${\varepsilon}_{e\mu}^A$. This is highly complementary to constraints from SNO data, which, differently from long-baseline neutral current data, is not sensitive to isospin conserving NSIs ${\varepsilon}_u^A$ = ${\varepsilon}_d^A$. Additionally, we disfavor large values of the diagonal vectorial NSI ${\varepsilon}_{\mu \mu}^{VV}$ and ${\varepsilon}_{\tau \tau}^V$ which originate from the LMA-Dark solution. We also highlight the complementarity between NSI searches at oscillation experiments using charged current and neutral current channels.

neutrino interactions↗

Emerging Tools to Support DILI Assessment in Clinical Trials with Abnormal Baseline Serum Liver Tests or Pre-existing Liver Diseases

Abstract Based on the late Dr. Hyman Zimmerman’s observation that hepatocellular drug-induced liver injury (DILI) leading to jaundice carries a ≥ 10% fatality risk (coined as Hy’s law by others), evaluation of Drug-Induced Serious Hepatotoxicity (eDISH) continues to play a central role in the assessment of a study drug’s liability for acute hepatocellular DILI. The eDISH identifies drugs in clinical trials with DILI fatality (death or transplant) risk that may be unacceptable in a post-market setting. As a two-dimensional graph that plots peak total bilirubin (TB) versus peak serum aminotransferase levels for each patient during study drug or comparator treatment, eDISH identifies potential cases of acute, modest, and serious hepatocellular DILI for in-depth analysis of liver tests (LT) and clinical course so that the likelihood of causal association with the study drug can be determined. Unfortunately, the generalizable utility of this tool only pertains to trials enrolling patients with normal or near normal (NNN) baseline (BL) serum LTs. The eDISH does not necessarily apply to trials of patients with abnormal baseline (ABN-BL) LTs that often coincide with underlying liver disorders. Because drug development programs being reviewed by the FDA increasingly target liver disorders, we are often challenged to evaluate DILI risk in trials of patients with ABN-BL LTs. Also, the high background prevalence of metabolic dysfunction associated steatotic liver disease (MASLD) means patients with LTs above NNN may need to be enrolled in trials treating non-liver disorders to reflect the target population. Such study populations create challenges for industry and regulators because eDISH may not reliably categorize or identify potential cases of DILI for further analysis, as it so efficiently does in NNN-BL trials. We describe the main functionalities of eDISH in NNN-BL trials to understand what should be emulated by new tools or eDISH modifications. We then discuss non-eDISH–based plots that may be useful in ABN-BL trials.

Amirzadegan, Jasmine↗

Setting a baseline for Integrated Landscape Design: Cost and risk assessment in herbaceous feedstock supply chains

The literature on bioenergy has pointed out that financial risks and limited performance benchmarks are leading barriers to wide-spread industry expansion. The purpose of this paper is to document a baseline cost and risk assessment from the perspective of biorefinery management for two herbaceous feedstocks, switchgrass and corn stover, in an application of Integrated Landscape Design (ILD). Integrating energy crops into row crops has attracted considerable attention leading to a variety of ways to implement ILD. However, variation in production conditions, different methods of implementing unit operations, and technology performance variability are among many factors leading to financial risk facing biorefineries from feedstock supply based on ILD. Utilizing data from field-based trials on switchgrass and corn stover in Virginia and Iowa in the United States, we estimate feedstock logistics cost and characterize it by a distribution of potential outcomes. The results show that, across fields included in the study, logistics cost for switchgrass vary from 73 per Mg to 171 per Mg. For corn stover, the inter-field variation in cost ranges from 83 per Mg to 105 per Mg. Results for intra-field uncertainty show that the cost for switchgrass ranges from 58 per Mg to 74 per Mg, and for corn stover they range from 50 per Mg to 65 per Mg. Furthermore, these results inform a baseline from which improvements in ILD can be compared, and provide biorefinery management with a starting point for cost and risk estimates of feedstock from ILD.

09 BIOMASS FUELS↗

Baseline blood levels of manganese, lead, cadmium, copper, and zinc in residents of Beijing suburb

Baseline blood concentrations of metals are important references for monitoring metal exposure in environmental and occupational settings. The purpose of this study was to determine the blood levels of manganese (Mn), copper (Cu), zinc (Zn), lead (Pb), and cadmium (Cd) among the residents (aged 12–60 years old) living in the suburb southwest of Beijing in China and to compare the outcomes with reported values in various developed countries. Blood samples were collected from 648 subjects from March 2009 to February 2010. Metal concentrations in the whole blood were determined by ICP-MS. The geometric means of blood levels of Mn, Cu, Zn, Pb and Cd were 11.4, 802.4, 4665, 42.6, and 0.68 µg/L, respectively. Male subjects had higher blood Pb than the females, while the females had higher blood Mn and Cu than the males. There was no gender difference for blood Cd and Zn. Smokers had higher blood Cu, Zn, and Cd than nonsmokers. There were significant age-related differences in blood levels of all metals studied; subjects in the 17–30 age group had higher blood levels of Mn, Pb, Cu, and Zn, while those in the 46–60 age group had higher Cd than the other age groups. A remarkably lower blood level of Cu and Zn in this population as compared with residents of other developed countries was noticed. Based on the current study, the normal reference ranges for the blood Mn were estimated to be 5.80–25.2 μg/L; for blood Cu, 541–1475 μg/L; for blood Zn, 2349–9492 μg/L; for blood Pb, <100 μg/L; and for blood Cd, <5.30 μg/L in the general population living in Beijing suburbs. - Highlights: • Baseline blood levels of metals in residents of Beijing suburb are investigated. • BMn and BPb in this cohort are higher than those in other developed countries. • Remarkably lower blood levels of Cu and Zn in this Chinese cohort are noticed. • The reference values for blood levels of Mn, Cu, Zn, Pb, and Cd are established.

54 ENVIRONMENTAL SCIENCES↗

Precision Measurements of Long-Baseline Neutrino Oscillation at LBNF

In a long-baseline neutrino oscillation experiment, the primary physics objectives are to determine the neutrino mass hierarchy, to determine the octant of the neutrino mixing angle θ 23 , to search for CP violation in neutrino oscillation, and to precisely measure the size of any CP-violating effect that is discovered. This presentation provides a brief introduction to these measurements and reports on efforts to optimize the design of a long-baseline neutrino oscillation experiment, the status of LBNE, and the transition to an international collaboration at LBNF.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Long-baseline quantum sensor network as dark matter haloscope

Ultralight dark photons constitute a well-motivated candidate for dark matter. A coherent electromagnetic wave is expected to be induced by dark photons when coupled with Standard-Model photons through kinetic mixing mechanism, and should be spatially correlated within the de Broglie wavelength of dark photons. Here we report the first search for correlated dark-photon signals using a long-baseline network of 15 atomic magnetometers, which are situated in two separated meter-scale shield rooms with a distance of about 1700 km. Both the network’s multiple sensors and the shields large size significantly enhance the expected dark-photon electromagnetic signals, and long-baseline measurements confidently reduce many local noise sources. Using this network, we constrain the kinetic mixing coefficient of dark photon dark matter over the mass range 4.1 feV-2.1 peV, which represents the most stringent constraints derived from any terrestrial experiments operating over the aforementioned mass range. Our prospect indicates that future data releases may go beyond the astrophysical constraints from the cosmic microwave background and the plasma heating.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗