Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “mortality”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 199 records · Page 11

Embryonic development during chronic acceleration

Experiments carried out on chicken eggs indicate that the embryo is affected during very early development, especially over the first four days, and during hatching. In the first four days, the brain develops as well as the anlage for all other organs. In addition, the heart commences to function and the extraembryonic membranes that compartmentalize the egg contents form. The latter require an appreciable extension and folding of tissue which may be disrupted by the mechanical load. Observations of embryonic abnormalities that occur during chronic acceleration suggest an inhibition of development of the axial skeleton, which is rarely seen otherwise, a general retardation of embryonic growth, and circulatory problems. The final stages of development (after 18 days) involve the uptake of fluids, the transition to aerial respiration, and the reorientation of the embryo into a normal hatching position. At 4 G mortality is very high during this period, with a majority of embryos failing to reorient into the normal hatching position.

Smith, A. H.↗

Hypergravity effects on litter size, nursing activity, prolactin, TSH, T3, and T4 in the rat

In a recent study of the effects of hypergravity (HG) on the reproductive system of the rat, it was found that the estrous cycle is perturbed in a pseudopregnancy-like pattern upon first exposure of animals to HG. This can be prevented by previous exposure to HG or by administration of bromergo cryptin. Adapted rats can mate and deliver in HG. However, little is known of the condition of the individual pregnant rat, fetuses, and newborn pups in this environment. There are also questions regarding the effects of HG on the number of fetuses, the mortality rate in different HG levels, and the effects on production and secretion of PRL and TSH. The present investigation is concerned with such questions, taking into account possible approaches to avoid or minimize the lethal effects of HG. The obtained results suggest that peripartum plasma PRL levels and thyroid hormone levels are critical for the survival of the litter.

Megory, E.↗

Stress assessment and spectral characterization of suspected acid deposition damage in red spruce (Picea Rubens) from Vermont

The effects of acid deposition on Picea rubens are studied. The Picea rubens located at Camels Hump Mt., Mt. Ascutney, and Ripton, VT were analyzed using stress level evaluations, in situ spectral data, pressure bomb analysis, and aircraft sensors. Spruce stress per circular plot and percent spruce mortality are calculated. The relation between stress levels and elevation and exposure and weather patterns is examined. It is observed that variations in the reflectance curves of the foliage and branches are related to cellular health, the type of cellular arrangement, and the degree of leaf tissue hydration; the leaf and twig specimens from high stress sites are more reflective in the red portion of the visible and less reflective in the NIR portion of the spectrum. The pressure bomb data reveal that the xylem water tension is higher in specimens from high stress sites. It is noted that remote sensing permits discrimination and mapping of suspected acid deposition damage.

Rock, B. N.↗

Effects of space shuttle launches STS-1 through STS-9 on terrestrial vegetation of John F. Kennedy Space Center, Florida

Space Shuttle launches produce a cloud containing hydrochloric acid (HCl), aluminum oxide (Al203), and other substances. Acidities of less than 0.5 pH have been measured routinely in association with the launch cloud. In an area of about 22 ha regularly exposed to the exhaust cloud during most Shuttle launches, acute vegetation damage has resulted from the first nine Shuttle launches. Changes include loss of sensitive species, loss of plant community structure, reduction in total cover, and replacement of some species by weedy invaders. Community level changes define a retrogressive sequence. One-time impacts to strand and dune vegetation occurred after launches of STS-8 and STS-9. Acute vegetation damage occurred especially to sensitive species. Within six months, however, recovery was nearly complete. Sensitivity of species to the launch cloud was partially predicted by previous laboratory studies. Far-field acidic and dry fallout from the cloud as it rises to stabilization and moves with the prevailing winds causes vegetation spotting. Damage from this deposition is minor; typically at most 1% to 5% of leaf surface area is affected. No plant mortality or community changes have occurred from far-field deposition.

Schmalzer, P. A.↗

Radiation protection guidelines for space missions

NASA's current radiation protection guidelines date from 1970, when the career limit was set at 400 rem. Today, using the same approach, but with the current risk estimates, a considerably lower career limit would obtain. Also, there is considerably more information about the radiation environments to be experienced in different missions than previously. Since 1970 women have joined the ranks. For these and other reasons it was necessary to reexamine the radiation protection guidelines. This task was undertaken by the National Council on Radiation Protection and Measurements Scientific Committee 75 (NCRP SC 75). Below the magnetosphere the radiation environment varies with altitude and orbit inclination. In outer space missions galactic cosmic rays, with the small but important heavy ion component, determine the radiation environment. The new recommendations for career dose limits, based on lifetime excess risk of cancer mortality, take into account age at first exposure and sex. The career limits range from 100 rem (4.0Sv) for a 24 year old female to 400 rem for a 55 year old male compared to the previous single limit of 400 rem (4.0 Sv). The career limit for the lens of the eye was reduced from 600 to 400 rem (6.0 to 4.0 Sv.)

Fry, R. J. M.↗

Late Wenlock (middle Silurian) bio-events: Caused by volatile boloid impact/s

Late Wenlockian (late mid-Silurian) life is characterized by three significant changes or bioevents: sudden development of massive carbonate reefs after a long interval of limited reef growth; sudden mass mortality among colonial zooplankton, graptolites; and origination of land plants with vascular tissue (Cooksonia). Both marine bioevents are short in duration and occur essentially simultaneously at the end of the Wenlock without any recorded major climatic change from the general global warm climate. These three disparate biologic events may be linked to sudden environmental change that could have resulted from sudden infusion of a massive amount of ammonia into the tropical ocean. Impact of a boloid or swarm of extraterrestrial bodies containing substantial quantities of a volatile (ammonia) component could provide such an infusion. Major carbonate precipitation (formation), as seen in the reefs as well as, to a more limited extent, in certain brachiopods, would be favored by increased pH resulting from addition of a massive quantity of ammonia into the upper ocean. Because of the buffer capacity of the ocean and dilution effects, the pH would have returned soon to equilibrium. Major proliferation of massive reefs ceased at the same time. Addition of ammonia as fertilizer to terrestrial environments in the tropics would have created optimum environmental conditions for development of land plants with vascular, nutrient-conductive tissue. Fertilization of terrestrial environments thus seemingly preceded development of vascular tissue by a short time interval. Although no direct evidence of impact of a volatile boloid may be found, the bioevent evidence is suggestive that such an impact in the oceans could have taken place. Indeed, in the case of an ammonia boloid, evidence, such as that of the Late Wenlockian bioevents may be the only available data for impact of such a boloid.

Berry, W. B. N.↗

Response of marine and freshwater algae to nitric acid and elevated carbon dioxide levels simulating environmental effects of bolide impact

One of the intriguing facets of the Cretaceous-Tertiary extinction is the apparently selective pattern of mortality amongst taxa. Some groups of organisms were severely affected and some remained relatively unscathed as they went through the K/T boundary. While there is argument concerning the exact interpretation of the fossil record, one of the best documented extinctions at the Cretaceous-Tertiary boundary is that of the calcareous nannoplankton. These organisms include coccolithic algae and foraminiferans. Attempts to explain their decline at the K/T boundary center around chemistry which could affect their calcium carbonate shells while leaving their silica-shelled cousins less affected or unaffected. Two environmental consequences of an extraterrestrial body impact which were suggested are the production of large quantities of nitrogen oxides generated by the shock heating of the atmosphere and the possible rise in CO2 from the dissolution of CaCO3 shells. Both of these phenomena would acidify the upper layers of the oceans and bodies of freshwater not otherwise buffered. The effects of nitric acid, carbon dioxide, or both factors on the growth and reproduction of calcareous marine coccoliths and non-calcareous marine and freshwater species of algae were considered. These experiments demonstrate that nitric acid and carbon dioxide have significant effects on important aspects of the physiology and reproduction of modern algae representative of extinct taxa thought to have suffered significant declines at the Cretaceous-Tertiary boundary. Furthermore, calcareous species showed more marked effects than siliceous species and marine species tested were more sensitive than freshwater species.

Boston, P. J.↗

The Karskiy craters are the probable records of catastrophe at the Cretaceous-Tertiary boundary

In order to corroborate the hypothesis of Alvarez and others about the connection of mass mortality and meteorite or cometary impact at the Cretaceous-Tertiary boundary, it is necessary to find a meteorite crater which was formed at the same time. Masaitiss suggested that the Karskiy craters (USSR) are suitable, but previous K/Ar data from other laboratories are very different (from 47 to 82 million years). Impact glasses were gathered from the Karskiy and Ust-Karskiy craters K/Ar age analyses were performed. The glasses cooled very rapidly and had the youngest model ages from 65.8 to 67.6 million years. The slower cooling crypto-crystalline aggregates had more ancient model ages, from 70.5 to 73.9 my as had tagamite because they captured excess argon during crystallization. Least squares analysis showed that with probability of 99 percent the findings on crypto-crystalline aggregates, tagamite and quartz glasses from the Karskiy and Ust-Karskiy craters lie on an isochron which has an age of 65.8 + or - 1.1 million years and a content of excess argon. For the two glasses with identical composition which have different quantities of secondary non-potassium minerals, an independent method determined the content of excess argon. Taking into account these data a more exact slope of the first isochron of 66.4 + or - 1.0 million years was observed and the second glass isochron with age 66.5 + or - 1.1 million years was constructed.

Kolesnikov, E. M.↗

Oblique impacts: Catastrophic vs. protracted effects

Proposed impacts as the cause of biologic catastrophes at the end of the Cretaceous and Eocene face several enigmas: protracted extinctions, even prior to the stratigraphic cosmogenic signature; widespread but non-uniform dispersal of the meteoritic component; absence of a crater of sufficient size; and evidence for massive intensive fires. Various hypotheses provide reasonable mechanisms for mass mortalities: global cooling by continental impact sites; global warming by oceanic impact sites; contrasting effects of asteroidal, cometary, and even multiple impacts; and stress on an already fragile global environment. Yet not every known large impact is associated with a major biologic catastrophe. An alternative is expanded: the consequences of an oblique impact. The most probable angle of impact is 45 deg with the probability for an impact at smaller angles decreasing: A vertical impact is as rare as a tangential impact with a 5 deg impact angle or less occurring only 8 percent of the time. Consequently a low-angle impact is a rare but probable event. Laboratory experiments at the NASA-Ames Vertical Gun Range reveal important information about cratering efficiency, impact vaporization, projectile dispersal, and phenomenology, thereby providing perspective for possible consequences of such an impact on both the Earth and Moon. Oblique impacts are rare but certain events through geologic time: A 5 deg impact by a 2 km-diameter impactor on the Earth would occur only once in about 18 my with a 10 km-diameter once in about 450 my. Major life extinctions beginning prior to the stratigraphic cosmogenic signature or protracted extinctions seemingly too long after the proposed event may not be evidence against an impact as a cause but evidence for a more complex but probable sequence of events.

Schultz, P. H.↗

Non-random cratering flux in recent time

Proposed periodic cycles of mass mortality have been linked to periodic changes in the impact flux on Earth. Such changes in the impact flux, however, also should be recorded on the Moon. Previous studies have concluded that the impact flux on the Moon over the last 1 to 2 billion years has been reasonably constant, but sudden changes in the impact flux over time intervals as short as 30 my could not be detected in these studies unless the added crater population greatly exceeded the cumulative cratering record. Consequently this study focuses only on bright-rayed craters larger than 1 km thereby not only limiting the study to recent craters but also largely eliminating contamination by secondary craters. Preservation of ray patterns and other fine-scale surface textures in the ejecta provides first-order culling of craters younger than Tycho, i.e., about 100 my. Although a periodic change in the impact flux in the Earth-Moon system cannot yet be confirmed from the data, a non-random component appears to exist with an increased flux around 7 and 15 my. The concentrations in different quadrants of the lunar hemisphere would be consistent with a shower of debris generally smaller than 0.5 km.

Schultz, P. H.↗

Volcanoes and global catastrophes

The search for a single explanation for global mass extinctions has let to polarization and the controversies that are often fueled by widespread media attention. The historic record shows a roughly linear log-log relation between the frequency of explosive volcanic eruptions and the volume of their products. Eruptions such as Mt. St. Helens 1980 produce on the order of 1 cu km of tephra, destroying life over areas in the 10 to 100 sq km range, and take place, on the average, once or twice a decade. Eruptions producing 10 cu km take place several times a century and, like Krakatau 1883, destroy life over 100 to 1000 sq km areas while producing clear global atmospheric effects. Eruptions producting 10,000 cu km are known from the Quaternary record, and extrapolation from the historic record suggests that they occur perhaps once in 20,000 years, but none has occurred in historic time and little is known of their biologic effects. Even larger eruptions must also exist in the geologic record, but documentation of their volume becomes increasingly difficult as their age increases. The conclusion is inescapable that prehistoric eruptions have produced catastrophes on a global scale: only the magnitude of the associated mortality is in question. Differentiation of large magma chambers is on a time scale of thousands to millions of years, and explosive volcanoes are clearly concentrated in narrow belts near converging plate margins. Volcanism cannot be dismissed as a producer of global catastrophes. Its role in major extinctions is likely to be at least contributory and may well be large. More attention should be paid to global effects of the many huge eruptions in the geologic record that dwarf those known in historic time.

Simkin, Tom↗

Analyses of risks associated with radiation exposure from past major solar particle events

Radiation exposures and cancer induction/mortality risks were investigated for several major solar particle events (SPE's). The SPE's included are: February 1956, November 1960, August 1972, October 1989, and the September, August, and October 1989 events combined. The three 1989 events were treated as one since all three could affect a single lunar or Mars mission. A baryon transport code was used to propagate particles through aluminum and tissue shield materials. A free space environment was utilized for all calculations. Results show the 30-day blood forming organs (BFO) limit of 25 rem was surpassed by all five events using 10 g/sq cm of shielding. The BFO limit is based on a depth dose of 5 cm of tissue, while a more detailed shield distribution of the BFO's was utilized. A comparison between the 5 cm depth dose and the dose found using the BFO shield distribution shows that the 5 cm depth value slightly higher than the BFO dose. The annual limit of 50 rem was exceeded by the August 1972, October 1989, and the three combined 1989 events with 5 g/sq cm of shielding. Cancer mortality risks ranged from 1.5 to 17 percent at 1 g/sq cm and 0.5 to 1.1 percent behind 10 g/sq cm of shielding for five events. These ranges correspond to those for a 45 year old male. It is shown that secondary particles comprise about 1/3 of the total risk at 10 g/sq cm of shielding. Utilizing a computerized Space Shuttle shielding model to represent a typical spacecraft configuration in free space at the August 1972 SPE, average crew doses exceeded the BFO dose limit.

Weyland, Mark D.↗

Radiation issues for piloted Mars mission

Current radiation risk for a piloted Mars mission is estimated using the idea of absorbed dose and ICRP-26, LET-dependent quality factors. In a spacecraft with aluminum walls (2 g/sq cm) at solar minimum the calculated dose equivalent is 0.73 Sv for a 406-day mission. Based on the current thinking this leads to an excess cancer mortality in a 35-year male of about 1 percent. About 75 percent of the dose equivalent is contributed by HZE particles and target fragments with average quality factors of 10.3 and 20, respectively. The entire concept of absorbed dose, quality factor, and dose equivalent as applied to such missions needs to be reexamined, in light of the fact that less than 50 percent of the nuclei in the body of the astronaut would have been traversed by a single GCR nuclei in the 406-day mission.

Badhwar, Gautam D.↗

Radiation exposure and risk assessment for critical female body organs

Space radiation exposure limits for astronauts are based on recommendations of the National Council on Radiation Protection and Measurements. These limits now include the age at exposure and sex of the astronaut. A recently-developed computerized anatomical female (CAF) model is discussed in detail. Computer-generated, cross-sectional data are presented to illustrate the completeness of the CAF model. By applying ray-tracing techniques, shield distribution functions have been computed to calculate absorbed dose and dose equivalent values for a variety of critical body organs (e.g., breasts, lungs, thyroid gland, etc.) and mission scenarios. Specific risk assessments, i.e., cancer induction and mortality, are reviewed.

Atwell, William↗

Radiation dose to critical body organs for October 1989 proton event

The Geostationary Operational Environmental Satellite (GOES-7) provides high-quality environmental data about the temporal development and energy characteristics of the protons emitted during a solar particle event. The GOES-7 time history of the hourly averaged integral proton flux for various particle kinetic energies are analyzed for the solar proton event occurring October 19-29, 1989. This event is similar to the August 1972 event that has been widely studied to estimate free-space and planetary radiation-protection requirements. By analyzing the time-history data, the dose rates, which can vary over many orders of magnitude in the early phases of the flare, can be estimated as well as the cumulative dose as a function of time. When basic transport results are coupled with detailed body organ thickness distributions calculated with the Computerized Anatomical Man and Computerized Anatomical Female models, the dose rates and cumulative doses to specific organs can be predicted. With these results, the risks of cancer incidence and mortality are estimated for astronauts in free space protected by various water shield thicknesses.

Simonsen, Lisa C.↗

Environmental monitoring of Space Shuttle launches at Kennedy Space Center - The first ten years

Space Shuttle launches produce local environmental effects through the generation of a launcher exhaust plume that in turn produces acidic depositions and acute vegetation damage in the near-field environment; fish kills have also been noted in the lagoon or impoundment near each of the launch pads. Repeated launches lead to cumulative changes in plant community composition and structure, and temporary decreases in pH due to acidification increases metal availability in soil microcosms and surface waters. Direct effects on terrestrial fauna include the mortality of birds, mammals, amphibians, and reptiles in the near-field area.

Schmalzer, Paul A.↗

Temporal analysis of the October 1989 proton flare using computerized anatomical models

The GOES-7 time history data of hourly averaged integral proton fluxes at various particle kinetic energies are analyzed for the solar proton event that occurred between October 19 and 29, 1989. By analyzing the time history data, the dose rates which may vary over many orders of magnitude in the early phases of the flare can be estimated as well as the cumulative dose as a function of time. Basic transport calculations are coupled with detailed body organ thickness distributions from computerized anatomical models to estimate dose rates and cumulative doses to 20 critical body organs. For a 5-cm-thick water shield, cumulative skin, eye, and blood-forming-organ dose equivalents of 1.27, 1.23, and 0.41 Sv, respectively, are estimated. These results are approximately 40-50 percent less than the widely used 0- and 5-cm slab dose estimates. The risk of cancer incidence and mortality are also estimated for astronauts protected by various water shield thicknesses.

Simonsen, L. C.↗

Toxicity study of dimethylethoxysilane (DMSES), the waterproofing agent for the Orbiter heat protective system

DMES, a volatile liquid, is used by NASA to waterproof the Orbiter thermal protective system. During waterproofing operations at the Oribter Processing Facility at KSC, workers could be exposed to DMES vapor. To assess the toxicity of DMES, acute and subchronic (2-week and 13-week) inhalation studies were conducted with rats. Studies were also conducted to assess the potential of DMES. Inhalation exposure concentrations ranged from 40 ppm to 4000 ppm. No mortality was observed during the studies. Exposures to 2100 ppm produced narcosis and ataxia. Post-exposure recovery from these CNS effects was rapid (less than 1 hr). These effects were concentration-dependent and relatively independent of exposure length. Exposure to 3000 ppm for 2 weeks (5 h/d, 5 d/wk) produced testicular toxicity. The 13-week study yielded similar results. Results from the genotoxicity assays (in vivo/in vitro unscheduled DNA synthesis in rat primary heptaocytes, chromosomal aberrations in rat bone marrow cells; reverse gene mutation in Salmonella typhimurium; and forward mutation in Chinese hamster culture cells) were negative. These studies indicated that DMES is mildly to moderately toxic but not a multagen.

Lam, Chiu-Wing↗