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At least 199 records · Page 11
All sourcesNASA NTRSDOE OSTI
NASA NTRS2010

A Combined Observational and Modeling Approach to Study Modern Dust Transport from the Patagonia Desert to East Antarctica

The understanding of present atmospheric transport processes from Southern Hemisphere (SH) landmasses to Antarctica can improve the interpretation of stratigraphic data in Antarctic ice cores. In addition, long range transport can deliver key nutrients normally not available to marine ecosystems in the Southern Ocean and may trigger or enhance primary productivity. However, there is a dearth of observational based studies of dust transport in the SH. This work aims to improve current understanding of dust transport in the SH by showing a characterization of two dust events originating in the Patagonia desert (south end of South America). The approach is based on a combined and complementary use of satellite retrievals (detectors MISR, MODIS, GLAS ,POLDER, OMI,), transport model simulation (HYSPLIT) and surface observations near the sources and aerosol measurements in Antarctica (Neumayer and Concordia sites). Satellite imagery and visibility observations confirm dust emission in a stretch of dry lakes along the coast of the Tierra del Fuego (TdF) island (approx.54deg S) and from the shores of the Colihue Huapi lake in Central Patagonia (approx.46deg S) in February 2005. Model simulations initialized by these observations reproduce the timing of an observed increase in dust concentration at the Concordia Station and some of the observed increases in atmospheric aerosol absorption (here used as a dust proxy) in the Neumayer station. The TdF sources were the largest contributors of dust at both sites. The transit times from TdF to the Neumayer and Concordia sites are 6-7 and 9-10 days respectively. Lidar observations and model outputs coincide in placing most of the dust cloud in the boundary layer and suggest significant de- position over the ocean immediately downwind. Boundary layer dust was detected as far as 1800 km from the source and approx.800 km north of the South Georgia Island over the central sub-Antarctic Atlantic Ocean. Although the analysis suggests the presence of dust at approx.1500 km SW of South Africa five days after, the limited capabilities of existing satellite platforms to differentiate between aerosol types do not permit a definitive conclusion. In addition, the model simulations show dust lifting to the free troposphere as it travels south but it could not be confirmed by the satellite observations due to cloudiness. This work demonstrates that complementary information from existing transport models, satellite and surface data can yield a consistent picture of the dust transport from the Patagonia desert to Antarctica. It also illustrates the limitation of using any of these approaches individually to characterize the transport of dust in a heavily cloudy area.

Gasso, S.↗
NASA NTRS2012

Radiation-Hard SpaceWire/Gigabit Ethernet-Compatible Transponder

A radiation-hard transponder was developed utilizing submicron/nanotechnology from IBM. The device consumes low power and has a low fabrication cost. This device utilizes a Plug-and-Play concept, and can be integrated into intra-satellite networks, supporting SpaceWire and Gigabit Ethernet I/O. A space-qualified, 100-pin package also was developed, allowing space-qualified (class K) transponders to be delivered within a six-month time frame. The novel, optical, radiation-tolerant transponder was implemented as a standalone board, containing the transponder ASIC (application specific integrated circuit) and optical module, with an FPGA (field-programmable gate array) friendly parallel interface. It features improved radiation tolerance; high-data-rate, low-power consumption; and advanced functionality. The transponder utilizes a patented current mode logic library of radiation-hardened-by-architecture cells. The transponder was developed, fabricated, and radhard tested up to 1 MRad. It was fabricated using 90-nm CMOS (complementary metal oxide semiconductor) 9 SF process from IBM, and incorporates full BIT circuitry, allowing a loop back test. The low-speed parallel LVCMOS (lowvoltage complementary metal oxide semiconductor) bus is compatible with Actel FPGA. The output LVDS (low-voltage differential signaling) interface operates up to 1.5 Gb/s. Built-in CDR (clock-data recovery) circuitry provides robust synchronization and incorporates two alarm signals such as synch loss and signal loss. The ultra-linear peak detector scheme allows on-line control of the amplitude of the input signal. Power consumption is less than 300 mW. The developed transponder with a 1.25 Gb/s serial data rate incorporates a 10-to-1 serializer with an internal clock multiplication unit and a 10-1 deserializer with internal clock and data recovery block, which can operate with 8B10B encoded signals. Three loop-back test modes are provided to facilitate the built-in-test functionality. The design is based on a proprietary library of differential current switching logic cells implemented in the standard 90-nm CMOS 9SF technology from IBM. The proprietary low-power LVDS physical interface is fully compatible with the SpaceWire standard, and can be directly connected to the SFP MSA (small form factor pluggable Multiple Source Agreement) optical transponder. The low-speed parallel interfaces are fully compatible with the standard 1.8 V CMOS input/output devices. The utilized proprietary annular CMOS layout structures provide TID tolerance above 1.2 MRad. The complete chip consumes less than 150 mW of power from a single 1.8-V positive supply source.

Katzman, Vladimir↗
NASA NTRS2012

The Marshall Space Flight Center Development of Mirror Modules for the ART-XC Ins1rument Aboard the Spectrum-Roentgen-Gamma Mission

The Spectrum-Rontgen-Gamma (SRG) mission is a Russian-German X-ray astrophysical observatory that carries two co-aligned and complementary X-ray telescope systems. The primary instrument is the German-led extended ROentgen Survey with an Imaging Telescope Array (eROSITA), a 7-module X-ray telescope system that covers the energy range from 0.2-12 keV. The complementary instrument is the Russian-led Astronomical Roentgen Telescope -- X-ray Concentrator (ART-XC or ART), a 7-module X-ray telescope system that provides higher energy coverage, up to 30 keV (with limited sensitivity above 12 keV).

Gubarev, M.↗
NASA NTRS2013

An Application of UAV Attitude Estimation Using a Low-Cost Inertial Navigation System

Unmanned Aerial Vehicles (UAV) are playing an increasing role in aviation. Various methods exist for the computation of UAV attitude based on low cost microelectromechanical systems (MEMS) and Global Positioning System (GPS) receivers. There has been a recent increase in UAV autonomy as sensors are becoming more compact and onboard processing power has increased significantly. Correct UAV attitude estimation will play a critical role in navigation and separation assurance as UAVs share airspace with civil air traffic. This paper describes attitude estimation derived by post-processing data from a small low cost Inertial Navigation System (INS) recorded during the flight of a subscale commercial off the shelf (COTS) UAV. Two discrete time attitude estimation schemes are presented here in detail. The first is an adaptation of the Kalman Filter to accommodate nonlinear systems, the Extended Kalman Filter (EKF). The EKF returns quaternion estimates of the UAV attitude based on MEMS gyro, magnetometer, accelerometer, and pitot tube inputs. The second scheme is the complementary filter which is a simpler algorithm that splits the sensor frequency spectrum based on noise characteristics. The necessity to correct both filters for gravity measurement errors during turning maneuvers is demonstrated. It is shown that the proposed algorithms may be used to estimate UAV attitude. The effects of vibration on sensor measurements are discussed. Heuristic tuning comments pertaining to sensor filtering and gain selection to achieve acceptable performance during flight are given. Comparisons of attitude estimation performance are made between the EKF and the complementary filter.

Eure, Kenneth W.↗
NASA NTRS2014

Cofactors in the RNA World

RNA world theories figure prominently in many scenarios for the origin and early evolution of life. These theories posit that RNA molecules played a much larger role in ancient biology than they do now, acting both as the dominant biocatalysts and as the repository of genetic information. Many features of modern RNA biology are potential examples of molecular fossils from an RNA world, such as the pervasive involvement of nucleotides in coenzymes, the existence of natural aptamers that bind these coenzymes, the existence of natural ribozymes, a biosynthetic pathway in which deoxynucleotides are produced from ribonucleotides, and the central role of ribosomal RNA in protein synthesis in the peptidyl transferase center of the ribosome. Here, we uses both a top-down approach that evaluates RNA function in modern biology and a bottom-up approach that examines the capacities of RNA independent of modern biology. These complementary approaches exploit multiple in vitro evolution techniques coupled with high-throughput sequencing and bioinformatics analysis. Together these complementary approaches advance our understanding of the most primitive organisms, their early evolution, and their eventual transition to modern biochemistry.

RNA↗
NASA NTRS2014

An Update on Oceanic Precipitation Rate and its Zonal Distribution in Light of Advanced Observations from Space

This study contributes to the estimation of the global mean and zonal distribution of oceanic precipitation rate using complementary information from advanced precipitation measuring sensors and provides an independent reference to assess current precipitation products. Precipitation estimates from the Tropical Rainfall Measuring Mission (TRMM) precipitation radar (PR) and CloudSat cloud profiling radar (CPR) were merged, as the two complementary sensors yield an unprecedented range of sensitivity to quantify rainfall from drizzle through the most intense rates. At higher latitudes, where TRMM PR does not exist, precipitation estimates from Aqua's Advanced Microwave Scanning Radiometer for Earth Observing System (AMSR-E) complemented CloudSat CPR to capture intense precipitation rates. The high sensitivity of CPR allows estimation of snow rate, an important type of precipitation at high latitudes, not directly observed in current merged precipitation products. Using the merged precipitation estimate from the CloudSat, TRMM, and Aqua platforms (this estimate is abbreviated to MCTA), the authors' estimate for 3-yr (2007-09) nearglobal (80degS-80degN) oceanic mean precipitation rate is approx. 2.94mm/day. This new estimate of mean global ocean precipitation is about 9% higher than that of the corresponding Climate Prediction Center (CPC) Merged Analysis of Precipitation (CMAP) value (2.68mm/day) and about 4% higher than that of the Global Precipitation Climatology Project (GPCP; 2.82mm/day). Furthermore, MCTA suggests distinct differences in the zonal distribution of precipitation rate from that depicted in GPCPand CMAP, especially in the Southern Hemisphere.

profiling radar↗
NASA NTRS2015

AWG Filter for Wavelength Interrogator

A wavelength interrogator is coupled to a circulator which couples optical energy from a broadband source to an optical fiber having a plurality of sensors, each sensor reflecting optical energy at a unique wavelength and directing the reflected optical energy to an AWG. The AWG has a detector coupled to each output, and the reflected optical energy from each grating is coupled to the skirt edge response of the AWG such that the adjacent channel responses form a complementary pair response. The complementary pair response is used to convert an AWG skirt response to a wavelength.

Black, Richard J.↗
NASA NTRS2017

Kits for Characterization of Chromosomal Inversions Using Probes

A kit for the characterization of chromosomal inversions using single-stranded probes that are either all identical or all complementary to a single-stranded chromatid is described. Reporter species are attached to oligonucleotide strands designed such that they may hybridize to portions of only one of a pair of single-stranded sister chromatids which may be prepared by the CO-FISH procedure. If an inversion has occurred, these marker probes will be detected on the second sister chromatid at the same location as the inversion on the first chromatid. The kit includes non-repetitive probes that are either all identical or all complementary to at least a portion of a target DNA sequence of only one DNA strand of only one chromatid and may in some embodiments include reagents suitable for performing CO-FISH and/or reagents for hybridizing the probes to the target DNA sequence.

Ray, F. Andrew↗
NASA NTRS2018

Air Traffic Management Technology Demonstration - 3 (ATD-3): Operational Concept for the Integration of ATD-3 Capabilities Version 1.0

ATD-3 has developed four capabilities to address its goal and objectives. The four ATD-3 capabilities include: Dynamic Weather Routes (DWR), Multi-Flight Common Routes (MFCR), Traffic Aware Strategic Aircrew Requests (TASAR), and Dynamic Routes for Arrivals in Weather (DRAW). This document describes the long-term, mature vision for the use and incorporation of the ATD-3 capabilities into the National Airspace System (NAS). This vision describes their complementary interaction and the benefit capture that accrues from use. Recognizing that all capabilities are unlikely to be implemented in unison, each of the capabilities is designed and able to be implemented independently. As discrete portions of the integrated capabilities are planned, additional integration efforts should be undertaken to validate the complementary interactions and benefit pool are realized from the selected subset.

ConOps↗
NASA NTRS2016

The Past and Future of AstroPAH Research and the Diffuse Interstellar Bands

Here, we present a critical assessment of the PAHs as DIB Carriers and discuss the progress and the advances that have been achieved so far through a series of complementary studies involving astronomical observations of DIBs, laboratory simulation of interstellar analogs for PAHs (neutrals and ions), space exposure experiments of PAHs, theoretical calculations of PAH spectra and the modeling of diffuse and translucent interstellar clouds. We will discuss what we have learned from these complementary studies, the constraints that can be derived from these studies for the PAHs as DIB carriers and the future studies that are required to address the open questions. These involve extending the laboratory and astronomical PAH-DIB studies from the NUV-Visible range into the NIR and MIR domains where DIBs have also been observed and developing tools in the laboratory to help generate more complex, PAH-related species for comparison with astronomical data. For the laboratory part, we will present the COSmIC facility at NASA-Ames that provides experimental conditions that closely mimic the interstellar conditions and helps address these issues. The comparison of astronomical data with laboratory data measured under realistic conditions is the only way to derive clear and unambiguous conclusions regarding the expected abundances for PAHs of various sizes and charge states in interstellar environments. From the observational aspect we will explore the new opportunities offered by JWST to connect the DIBs to MIR PAH emission and to search for NIR DIBs that may trace the presence of PAHs.

Salama, Farid↗
NASA NTRS2018

SCExAO/CHARIS Near-Infrared Direct Imaging, Spectroscopy, and Forward-Modeling of κ and b: A Likely Young, Low-Gravity Superjovian Companion

We present SCExAO/CHARIS high-contrast imaging/JHK integral field spectroscopy of κ And b, a directly imaged low-mass companion orbiting a nearby B9V star. We detect κ And b at a high signal-to-noise ratio and extract high-precision spectrophotometry using a new forward-modeling algorithm for (A-)LOCI complementary to KLIP-FM developed by Pueyo et al. κ And b’s spectrum best resembles that of a low-gravity L0–L1 dwarf (L0–L1γ). Its spectrum and luminosity are very well matched by 2MASS J0141-4633 and several other 12.5–15 M(sub J) free-floating members of the 40 Myr old Tuc–Hor Association, consistent with a system age derived from recent interferometric results for the primary, a companion mass at/near the deuterium-burning limit (13(sup +12, sub -2) M(sub J)), and a companion-to-primary mass ratio characteristic of other directly imaged planets (q ∼ 0.005(sup +0.005, sub -0.001)). We did not unambiguously identify additional, more closely orbiting companions brighter and more massive than κ And b down to ρ ∼ 0".3 (15 au). SCExAO/CHARIS and complementary Keck/NIRC2 astrometric points reveal clockwise orbital motion. Modeling points toward a likely eccentric orbit: a subset of acceptable orbits include those that are aligned with the star’s rotation axis. However, κ And b’s semimajor axis is plausibly larger than 55 au and in a region where disk instability could form massive companions. Deeper high-contrast imaging of κ And and low-resolution spectroscopy from extreme adaptive optics systems such as SCExAO/CHARIS and higher-resolution spectroscopy from Keck/OSIRIS or, later, IRIS on the Thirty Meter Telescope could help to clarify κ And b’s chemistry and whether its spectrum provides an insight into its formation environment.

Currie, Thayne↗
NASA NTRS2016

Spacecraft Vibration Testing: Benefits and Potential Issues

JPL has traditionally performed system level vibration testing of flight spacecraft. The benefits and potential issues of fully assembled flight spacecraft vibration testing are discussed herein. The following specific topics, which may be complementary to the special session on “Virtual Vibration Testing,” are discussed: spacecraft workmanship, functional and structural integrity testing to uncover workmanship problems, force- and moment-limited vibration testing, potential issues with structural frequency identification using base shake test data, and several failures related to vibration shaker testing. The information provided in this paper is complementary to the special session on “Virtual Shaker Testing,’ and attention is given to issues that virtual shaker testing may face.

Kolaini, Ali R.↗
NASA NTRS2020

Encealdus Orbilander: A Flagship Mission Concept for Astrobiology

"Whether life exists beyond Earth remains a fundamental question driving our exploration of the Solar System. At Saturn’s moon Enceladus, plumes of oceanic material vented into space allow the investigation of the astrobiological potential of an ocean world, hinted at by Cassini, without the necessity of drilling through kilometers of ice crust. The Enceladus Orbilander is a flagship ($2.56B in fiscal year 2025 dollars) mission concept created for the 2023–2033 Planetary Science Decadal Survey. Orbilander takes full advantage of the opportunity provided by Enceladus’ plumes to search for signs of life. A single spacecraft both orbits and lands, capturing samples from four distinct reservoirs offered by the plumes. These samples, both particulate and vapor, are then analyzed by the Life Detection Suite (LDS), a set of five instruments conducting complementary and orthogonal biosignature-seeking measurements. To provide the context that specifically enhances interpretation of LDS measurements, geochemical and geophysical investigations are conducted both in orbit and on the surface. These reveal the physio-chemical state of the ocean and core as well as the processes involved in ejection of plume material and how these affect the ocean material analyzed by the LDS. The Orbilander can be delivered to the Saturn system via several launch vehicle and trajectory options, including a direct trajectory (7-year cruise), a ∆V-EGA trajectory (9-year cruise) and several options using an inner cruise with Venus and Earth flybys (10-year cruise). Upon Saturn Orbit Insertion, a 4-year moon tour pumps down the Orbilander’s orbit to intercept Enceladus. The most optimal arrival times balance the Jupiter flyby opportunities of the late 2030s and solar illumination at the Enceladus high southern latitudes where plume material is most abundant. This mission concept therefore targets project start in 2030. Upon Enceladus Orbit Insertion, the Orbilander begins a 1.5-year-long campaign of landing site reconnaissance, remote sensing science, and collecting sufficient plume sample to run all but one of the LDS measurements. After successful landing, the Orbilander spends 2 years on the surface conducting multiple LDS measurements with all five instruments on actively and passively collected plume material, as well as seismic investigations. The schedule laid out here is well-defined, but the mission also has operational and resource flexibility should additional reconnaissance be needed. As part of the design study, mission and development risks were identified and mitigation strategies proposed. Technologies key to achieving the life detection science objectives include instrumentation matured under programs like COLDTech and ICEE-2, such as aspects of the sampling system and microfluidic devices, as well as well-known techniques like high-resolution and separation-capable mass spectrometers. Autonomous onboard navigation is planned to maintain a halo orbit around Enceladus to enable passive sampling from orbit as well as reconnaissance measurements for use in site selection and landing. Terrain relative navigation is included to ensure safe landing, given that targeted areas may contain landing hazards. Continued development of radioisotope thermoelectric generator (RTG) technology and long-life batteries is essential for this long duration mission. The Enceladus Orbilander represents an optimal point in the trade space of science value versus cost, taking advantage of the extensive knowledge of Enceladus provided by Cassini, how well Enceladus lends itself to a search for life in material from its ocean, and the flexibility afforded by the innovative design developed by the APL team. By taking full advantage of Enceladus’ plumes both in orbit and on the surface, Orbilander represents a robust search for life with complementary and orthogonal biosignatures as well as contextual geophysical and geochemical measurements, determining not only whether Enceladus is inhabited (at levels up to 500,000× scarcer than in Earth’s oceans) but also why. "

Exobiology↗
NASA NTRS2017

Wavefront sensing for a future HabEx space telescope.

HabEx is a concept study for a next generation space telescope having a 4 to 6.5 m primary mirror diameter. Primarily designed for exoplanet science, but also carrying general astrophysics instruments, it will have stability requirements orders of magnitude more stringent than any previously flown space-based observatory. Wavefront control, including active sensing/control of wavefront jitter and drift, will be essential to achieving and maintaining coronagraph performance. There are currently two complementary techniques that can be used to sense the wavefront drift. An attractive method is to use starlight rejected from the coronagraph to sense changes in the wavefront incident on the coronagraph mask. This method suffers from photon noise especially when imaging dim stars. It is also unavailable during slews between target stars. Laser metrology is a complementary system in which a laser “truss” enables rigid body displacements of the optics to be measured from changes in the separation of pairs of optical fiducials which can be separated by many meters. In closed loop with actuated optics, laser metrology actively maintains rigid body alignment of the front-end optics, thereby eliminating the dominant source of wavefront drift. This method can maintain rigid body stability of the telescope optics and thereby wavefront control, even during slews between targets.

Martin, Stefan↗
NASA NTRS2021

Improved Estimates of Pentad Precipitation through the Merging of Independent Precipitation Datasets

Three independent, quasi-global, gridded datasets of precipitation (a rain gauge-based dataset, the satellite-only component of the NASA Integrated Multi-satellitE Retrievals for Global Precipitation Measurement mission [IMERG] Final Run precipitation product, and precipitation estimates derived from NASA Soil Moisture Active Passive [SMAP] soil moisture retrievals), are objectively combined into a single pentad precipitation dataset at 36-km resolution using a unique approach based on extended triple collocation. The quality of each of the four datasets is then evaluated against independent observations. When a global land surface model at 36-km resolution is integrated four times, once utilizing the merged precipitation forcing and once with each of the three contributing datasets, the near-surface soil moisture variations produced with the merged forcing validate best against independent satellite-based soil moisture fields. In addition, the merged dataset is found to be more consistent, relative to each contributor, with estimates of air temperature variations across the globe. The merged dataset thus appears to draw successfully on the complementary strengths of each contributor: the particularly high quality of the rain gauge-based dataset in areas of high gauge density, the more uniform accuracy across the globe of the IMERG data, and the moderate accuracy, particularly in semi-arid regions, of the soil moisture retrieval-based data. Plain Language Summary Obtaining measurements of precipitation across the globe can be challenging. Rain gauges in some ways provide the most accurate measurements, but gauges are absent in many parts of the world, and even where they exist, they only measure precipitation at the gauge itself and therefore may not provide an accurate large-scale average. Satellite-based estimates of precipitation largely overcome these problems, but such data have their own issues, notably a “snapshot” (rather than a time-average) character of the measurements and difficulty associated with interpreting the measured radiances in the presence of complex land surfaces. In the present paper, we use a novel approach to generate a “merged” dataset, one that optimally combines the gauge precipitation information and the satellite-based precipitation information with a third set of estimates derived from soil moisture retrievals. The merged precipitation dataset and each of the three contributors (aggregated here to 5-day averages at a spatial resolution of about 36-km) are then evaluated for consistency with independent geophysical fields. The merged dataset is found to perform best, a clear indication that it takes proper advantage of the complementary strengths of each contributor and, accordingly, that the presented approach for merging the different contributors is indeed viable.

Precipitation↗
NASA NTRSDate not supplied

Evaluation of Present and Future Spaceborne Lightning Observations During the ALOFT Campaign

The ALOFT1 campaign took place during July 2023. The NASA ER-2 high-altitude aircraft was based in Tampa, Florida, and flew approximately 60 hours sampling tropical and sub-tropical thunderstorms that were mostly contained within the common fields of view of GLM4-16 and GLM-18. In addition, multiple underflights of the ISS LIS5 instrument occurred. The FEGS2 and LIP6 instrument suite on the ER-2 provided a combination of multispectral optical, slow and fast electric field change, and three-dimensional electric field measurements of lightning and thunderstorms. Notably, in addition to the 777-nm band used by GLM and LIS, FEGS also observed at 337 nm, 500 nm, 868 nm, wideband visible-to-infrared, and shortwave infrared. A spectrometer that spanned most major lightning bands from the ultraviolet to infrared was included. Observations of gamma-ray production by thunderstorms were also collected during ALOFT. Thus, the lightning-observing suite on the ER-2 during ALOFT provides an unprecedented suborbital dataset for direct optical-to-optical and indirect radio-to-optical validation of existing spaceborne lightning sensors like GLM and LIS. In addition, the multispectral observations from FEGS enables evaluation of current and future spaceborne lightning-observing concepts. For example, the 337-nm channel is relevant to both existing missions like ASIM7 as well as future concepts like the CubeSpark mission currently being formulated by NASA. Complementary to LIS, the ISS also carries the STP-H88 payload, which features microwave radiometers covering 18-182 GHz, while the ER-2 carried radiometers covering 10-684 GHz, enabling evaluation of spaceborne passive microwave measurements that are complementary to the lightning observations. 1. Airborne Lightning Observatory for FEGS2 and TGFs3 2. Fly’s Eye GLM4 Simulator 3. Terrestrial Gamma-ray Flashes 4. Geostationary Lightning Mapper 5. International Space Station Lightning Imaging Sensor 6. Lightning Instrument Package 7. Atmosphere-Space Interactions Monitor 8. 8th Space Test Program – Houston mission

Timothy Lang↗
NASA NTRS2025

Habitability and Human Factors Assessment (iSHORT, SHAQ, and SHU)

BACKGROUND As long-duration off-planet habitats become a reality, a consideration of habitability and human factors (HF) is crucial. The habitat is more than just a place to live and work. It is also the crew’s perception of the space, and the psychological impacts of size, layout, and usage over time; all of which can support or strain behavioral health and performance (BHP). A previous International Space Station (ISS) habitability study used the iSHORT (Space Habitability Observation Reporting Tool) to collect detailed data about habitability and human factors and inform NASA Standards. Of the previous iSHORT study, only one of the six ISS subjects had a duration of one year; all other ISS and ground analog subjects had shorter mission durations from one week to six months. It is necessary to collect new data with a focus on long-duration exploration missions of > 6 months and on planetary surface habitat design. New data is also needed to compare the iSHORT to other habitability measures. One measure, the SHAQ (Subjective Habitability and Acceptability Questionnaire), assesses the intersection of psychology and habitability. Another complementary measure, the Scale for Habitat Usability (SHU), is a brief subjective scale that captures how habitat design impacts perceived usability of the built environment in relation to task performance. OBJECTIVE Our study aims to (1) understand how individual well-being and team dynamics may relate to HF concerns over time, (2) capture how habitability and HF change over time, (3) compare the three habitability measures (iSHORT, SHAQ, SHU), (4) assess habitats to capture HF design concerns and related BHP impacts of a planetary habitat, and (5) inform future standards for HF design. METHOD Data are being collected on crews living and working in long-duration spaceflight analogs. Individual-level data collections are repeated at regular intervals throughout the missions on several habitat areas, activities, and key equipment (i.e., points of interest). These points of interest (POIs) include the kitchen/galley, crew quarters, and other work and living areas. Assessments include evaluations of privacy, comfort, convenience, control, efficiency, and social density through the lens of subsequent outcomes like sleep, individual performance, group activities performance, stress, mood, and social interactions. Pre- and post-mission evaluations will also allow comparison with homes, pre- and post-mission hotels, and a retrospective reflection of living and working in a long-duration analog. INITIAL DATA COLLECTIONS In this poster, we will describe the measures and data yield. Since the research protocol was designed, the study team has collected iSHORT Standalone four times, nine collections of SHAQ, and three collections of iSHORT with SHAQ. Data collection is ongoing. SUMMARY A novel assessment suite has been developed to further aid the comparison and complementary understanding of the habitability and human factors measures, which will allow for efficient deployment of these measures in analogs and/or spaceflight in near-term research as well as support well-being and performance through design.

J C W Miller↗
NASA NTRS1997

Csa-19, a radiation-responsive human gene, identified by an unbiased two-gel cDNA library screening method in human cancer cells

A novel polymerase chain reaction (PCR)-based method was used to identify candidate genes whose expression is altered in cancer cells by ionizing radiation. Transcriptional induction of randomly selected genes in control versus irradiated human HL60 cells was compared. Among several complementary DNA (cDNA) clones recovered by this approach, one cDNA clone (CL68-5) was downregulated in X-irradiated HL60 cells but unaffected by 12-O-tetradecanoyl phorbol-13-acetate, forskolin, or cyclosporin-A. DNA sequencing of the CL68-5 cDNA revealed 100% nucleotide sequence homology to the reported human Csa-19 gene. Northern blot analysis of RNA from control and irradiated cells revealed the expression of a single 0.7-kilobase (kb) messenger RNA (mRNA) transcript. This 0.7-kb Csa-19 mRNA transcript was also expressed in a variety of human adult and corresponding fetal normal tissues. Moreover, when the effect of X- or fission neutron-irradiation on Csa-19 mRNA was compared in cultured human cells differing in p53 gene status (p53-/- versus p53+/+), downregulation of Csa-19 by X-rays or fission neutrons was similar in p53-wild type and p53-null cell lines. Our results provide the first known example of a radiation-responsive gene in human cancer cells whose expression is not associated with p53, adenylate cyclase or protein kinase C.

NASA Discipline Radiation Health↗