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At least 199 records · Page 11

Feasibility of Mossbauer survey meter for hydrocarbon and mineral reserves

The feasibility of developing a Mossbauer survey meter for geophysical prospecting was investigated. Various critical requirements that will have to be met by the source and absorber crystals in such an instrument were identified. It was concluded that a survey meter based on (Rh-103 resonance (40 kev) yields Rh-103) isomeric transition is feasible and should be developed.

Singh, J. J.↗

Highball: A high speed, reserved-access, wide area network

A network architecture called Highball and a preliminary design for a prototype, wide-area data network designed to operate at speeds of 1 Gbps and beyond are described. It is intended for applications requiring high speed burst transmissions where some latency between requesting a transmission and granting the request can be anticipated and tolerated. Examples include real-time video and disk-disk transfers, national filestore access, remote sensing, and similar applications. The network nodes include an intelligent crossbar switch, but have no buffering capabilities; thus, data must be queued at the end nodes. There are no restrictions on the network topology, link speeds, or end-end protocols. The end system, nodes, and links can operate at any speed up to the limits imposed by the physical facilities. An overview of an initial design approach is presented and is intended as a benchmark upon which a detailed design can be developed. It describes the network architecture and proposed access protocols, as well as functional descriptions of the hardware and software components that could be used in a prototype implementation. It concludes with a discussion of additional issues to be resolved in continuing stages of this project.

Mills, David L.↗

Status Update on the Seal/bearing Rotordynamics Test Facility at Case Western Reserve University

The CWRU Seal/Bearing test facility is shown along with the revised force measuring system. This facility has recently been retrofitted with a high pressure, high flow oil system. The high pressure high flow water system remains in place to test seals. Also, a new high flow air system is now installed. Thus, testing to determine static and dynamic properties can now be performed using oil, water, or air on this single facility. The oil system is currently being used to determine rotordynamic properties of a NASA four pocket hydrostatic journal bearing. The revised dual system force measuring configuration is performing with excellent accuracy. That is, the dynamic force measurements are made simultaneously with two independent systems, one with piezoelectric load cells and the other with strain gage load cells. The difference is less than 2 pct. between these two sets of load cell measurements on recent tests with a static eccentricity set close to zero and an orbit radius of 0.0004 inch. The extracted stiffness, damping and inertia coefficients is given for the test conditions shown, as extracted from the two independent dynamic force measurements.

Adams, Michael L.↗

Contractile reserve and calcium regulation are depressed in myocytes from chronically unloaded hearts

BACKGROUND: Chronic cardiac unloading of the normal heart results in the reduction of left ventricular (LV) mass, but effects on myocyte contractile function are not known. METHODS AND RESULTS: Cardiac unloading and reduction in LV mass were induced by heterotopic heart transplantation to the abdominal aorta in isogenic rats. Contractility and [Ca(2+)](i) regulation in LV myocytes were studied at both 2 and 5 weeks after transplantation. Native in situ hearts from recipient animals were used as the controls for all experiments. Contractile function indices in myocytes from 2-week unloaded and native (control) hearts were similar under baseline conditions (0.5 Hz, 1.2 mmol/L [Ca(2+)](o), and 36 degrees C) and in response to stimulation with high [Ca(2+)](o) (range 2.5 to 4.0 mmol/L). In myocytes from 5-week unloaded hearts, there were no differences in fractional cell shortening and peak-systolic [Ca(2+)](i) at baseline; however, time to 50% relengthening and time to 50% decline in [Ca(2+)](i) were prolonged compared with controls. Severe defects in fractional cell shortening and peak-systolic [Ca(2+)](i) were elicited in myocytes from 5-week unloaded hearts in response to high [Ca(2+)](o). However, there were no differences in the contractile response to isoproterenol between myocytes from unloaded and native hearts. In 5-week unloaded hearts, but not in 2-week unloaded hearts, LV protein levels of phospholamban were increased (345% of native heart values). Protein levels of sarcoplasmic reticulum Ca(2+) ATPase and the Na(+)/Ca(2+) exchanger were not changed. CONCLUSIONS: Chronic unloading of the normal heart caused a time-dependent depression of myocyte contractile function, suggesting the potential for impaired performance in states associated with prolonged cardiac atrophy.

NASA Discipline Cardiopulmonary↗

Estimation of cardiac reserve by peak power: validation and initial application of a simplified index

OBJECTIVES: To validate a simplified estimate of peak power (SPP) against true (invasively measured) peak instantaneous power (TPP), to assess the feasibility of measuring SPP during exercise and to correlate this with functional capacity. DESIGN: Development of a simplified method of measurement and observational study. SETTING: Tertiary referral centre for cardiothoracic disease. SUBJECTS: For validation of SPP with TPP, seven normal dogs and four dogs with dilated cardiomyopathy were studied. To assess feasibility and clinical significance in humans, 40 subjects were studied (26 patients; 14 normal controls). METHODS: In the animal validation study, TPP was derived from ascending aortic pressure and flow probe, and from Doppler measurements of flow. SPP, calculated using the different flow measures, was compared with peak instantaneous power under different loading conditions. For the assessment in humans, SPP was measured at rest and during maximum exercise. Peak aortic flow was measured with transthoracic continuous wave Doppler, and systolic and diastolic blood pressures were derived from brachial sphygmomanometry. The difference between exercise and rest simplified peak power (Delta SPP) was compared with maximum oxygen uptake (VO(2)max), measured from expired gas analysis. RESULTS: SPP estimates using peak flow measures correlated well with true peak instantaneous power (r = 0.89 to 0.97), despite marked changes in systemic pressure and flow induced by manipulation of loading conditions. In the human study, VO(2)max correlated with Delta SPP (r = 0.78) better than Delta ejection fraction (r = 0.18) and Delta rate-pressure product (r = 0.59). CONCLUSIONS: The simple product of mean arterial pressure and peak aortic flow (simplified peak power, SPP) correlates with peak instantaneous power over a range of loading conditions in dogs. In humans, it can be estimated during exercise echocardiography, and correlates with maximum oxygen uptake better than ejection fraction or rate-pressure product.

Non-NASA Center↗