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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 199 records · Page 11
All sourcesNASA NTRSDOE OSTI
DOE OSTI2020

Effects of Electrical Stimulation on hiPSC-CM Responses to Classic Ion Channel Blockers

Abstract Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) hold great potential for personalized cardiac safety prediction, particularly for that of drug-induced proarrhythmia. However, hiPSC-CMs fire spontaneously and the variable beat rates of cardiomyocytes can be a confounding factor that interferes with data interpretation. Controlling beat rates with pacing may reduce batch and assay variations, enable evaluation of rate-dependent drug effects, and facilitate the comparison of results obtained from hiPSC-CMs with those from adult human cardiomyocytes. As electrical stimulation (E-pacing) of hiPSC-CMs has not been validated with high-throughput assays, herein, we compared the responses of hiPSC-CMs exposed with classic cardiac ion channel blockers under spontaneous beating and E-pacing conditions utilizing microelectrode array technology. We found that compared with spontaneously beating hiPSC-CMs, E-pacing: (1) reduced overall assay variabilities, (2) showed limited changes of field potential duration to pacemaker channel block, (3) revealed reverse rate dependence of multiple ion channel blockers on field potential duration, and (4) eliminated the effects of sodium channel block on depolarization spike amplitude and spike slope due to a software error in acquiring depolarization spike at cardiac pacing mode. Microelectrode array optogenetic pacing and current clamp recordings at various stimulation frequencies demonstrated rate-dependent block of sodium channels in hiPSC-CMs as reported in adult cardiomyocytes. In conclusion, pacing enabled more accurate rate- and concentration-dependent drug effect evaluations. Analyzing responses of hiPSC-CMs under both spontaneously beating and rate-controlled conditions may help better assess the effects of test compounds on cardiac electrophysiology and evaluate the value of the hiPSC-CM model.

Wei, Feng↗
DOE OSTI2025

BAGELS for simultaneous polarization, orbit, and optics control in electron storage rings

We present a new method for minimizing the effects of radiative depolarization in electron storage rings by use of a minimal number of special vertical orbit bumps. The bumps can be used to minimize the effects of radiative depolarization while simultaneously maintaining other common benefits of vertical orbits, e.g., transverse coupling and vertical dispersion control. Because simultaneously optimizing the large number of vertical correctors in a ring is operationally infeasible, we use dimensionality reduction to define a minimal number of the most effective groups of vertical correctors that can be optimized during operation, motivating the name “Best Adjustment Groups for ELectron Spin” (BAGELS). The method is streamlined by using suitable “basis bumps” instead of all individual vertical correctors. We define three types of basis bumps for different purposes: (i) generates no delocalized transverse coupling nor delocalized vertical dispersion, (ii) generates no delocalized vertical dispersion, and (iii) generates no delocalized transverse coupling. BAGELS has been essential in the design of the Electron Storage Ring (ESR) of the Electron-Ion Collider (EIC) and will be beneficial for any polarized electron ring, including FCC-ee. HERA and LEP would have likely benefitted as well. We use BAGELS to significantly increase polarization in the 18 GeV EIC-ESR, beyond what is achievable with conventional methods; in the 1-IP lattice, we nearly double the asymptotic polarization, and in the 2-IP lattice, we more than triple the asymptotic polarization. We also use BAGELS to construct knobs that can be used for global coupling correction, and knobs that generate vertical emittance for beam size matching, all while having minimal impacts on the polarization and orbit/optics. Published by the American Physical Society 2025

43 PARTICLE ACCELERATORS↗
DOE OSTI2022

Spontaneous Polarization in an Ultrathin Improper-Ferroelectric/Dielectric Bilayer in a Capacitor Structure at Cryogenic Temperatures

To determine the effect of depolarization and the critical thickness in improper-ferroelectric hexagonal-ferrite thin films, we investigate the polarization switching of a ferroelectric/dielectric bilayer in capacitor structures at 20 K. Experimentally, we show that the spontaneous polarization persists throughout the studied thickness range (3 to 80 unit cell), even with a thick (10-nm) dielectric layer, suggesting no practical thickness limit for applications. By fitting the effect of depolarization using the phenomenological theory, we show that the spontaneous polarization remains finite when the thickness of the ferroelectric layer approaches zero, providing a hint for the absence of critical thickness. We also find that the interfacial effects limit the multidomain formation and govern the polarization switching mechanisms.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗
DOE OSTI2020

Control of polymorphism during epitaxial growth of hyperferroelectric candidate LiZnSb on GaSb (111)B

A major challenge for ferroelectric devices is the depolarization field, which competes with and often destroys long-range polar order in the limit of ultrathin films. Recent theoretical predictions suggest a new class of materials, termed hyperferroelectics, that should be robust against the depolarization field and enable ferroelectricity down to the monolayer limit. Here, the authors demonstrate the epitaxial growth of hexagonal LiZnSb, one of the hyperferroelectric candidate materials, by molecular-beam epitaxy on GaSb (111)B substrates. Due to the high volatility of all three atomic species, they find that LiZnSb can be grown in an adsorption-controlled window, using an excess zinc flux. Within this window, the desired polar hexagonal phase is stabilized with respect to a competing cubic polymorph, as revealed by x-ray diffraction and transmission electron microscopy measurements. First-principles calculations show that for moderate amounts of epitaxial strain and moderate concentrations of Li vacancies, the cubic LiZnSb phase is lower in formation energy than the hexagonal phase, but only by a few millielectronvolts per formula unit. Therefore, they suggest that kinetics plays a role in stabilizing the desired hexagonal phase at low temperatures. Their results provide a path toward experimentally demonstrating ferroelectricity and hyperferroelectricity in a new class of ternary intermetallic compounds.

42 ENGINEERING↗
DOE OSTI2021

The challenges of beam polarization and keV-scale centre-of-mass energy calibration at the FCC-ee

The capability to determine the FCC-ee centre-of-mass energies (ECM) at the ppm level using resonant depolarization of the beams is essential for the Z line shape measurements, the W mass and the possible observation of the Higgs boson s-channel production. A first analysis (Blondel A et al Polarization and centre-of-mass energy calibration at FCC-ee. demonstrated the feasibility of this programme, conditional to careful preparation and a number of further developments. The existing simulation codes must be unified; the analysis and design of the instrumentation must be developed; and a detailed planning must be developed for the simultaneous and coordinated operation of the accelerator, of the continuous polarization and depolarization measurements, and of the beam monitoring devices, ensuring a precise extrapolation from beam energies to centre-of-mass energy and energy spread.

43 PARTICLE ACCELERATORS↗
DOE OSTI2021

Polarimetric Radar Variables in Snowfall at Ka- and W-Band Frequency Bands: A Comparative Analysis

Dual-frequency millimeter-wavelength radar observations in snowfall are analyzed in order to evaluate differences in conventional polarimetric radar variables such as differential reflectivity (ZDR) specific differential phase shift (K DP ) and linear depolarization ratio (LDR) at traditional cloud radar frequencies at Ka and W bands (~35 and ~94 GHz, correspondingly). Low radar beam elevation (~5°) measurements were performed at Oliktok Point, Alaska, with a scanning fully polarimetric radar operating in the horizontal–vertical polarization basis. This radar has the same gate spacing and very close beam widths at both frequencies, which largely alleviates uncertainties associated with spatial and temporal data matching. It is shown that observed Ka- and W-band Z DR differences are, on average, less than about 0.5 dB and do not have a pronounced trend as a function of snowfall reflectivity. The observed Z DR differences agree well with modeling results obtained using integration over nonspherical ice particle size distributions. For higher signal-to-noise ratios, KDP data derived from differential phase measurements are approximately scaled as reciprocals of corresponding radar frequencies indicating that the influence of non-Rayleigh scattering effects on this variable is rather limited. This result is also in satisfactory agreement with data obtained by modeling using realistic particle size distributions. Observed Ka- and W-band LDR differences are strongly affected by the radar hardware system polarization “leak” and are generally less than 4 dB. Smaller differences are observed for higher depolarizations, where the polarization “leak” is less pronounced. Realistic assumptions about particle canting and the system polarization isolation lead to modeling results that satisfactorily agree with observational dual-frequency LDR data.

42 ENGINEERING↗
DOE OSTI2021

Afterpulse correction for micro-pulse lidar to improve middle and upper tropospheric aerosol measurements

Micro-pulse lidar (MPL) measurements have been widely used in atmospheric research over the past few decades. However, the MPL afterpulse noise has a large impact on the MPL aerosol measurement in the middle and upper troposphere, and an effective correction method is still lacking. Here, a new afterpulse correction approach is presented by using measurements with low-level optically thick clouds to act as the lids blocking atmospheric signals beyond the clouds completely. Examples are provided to illustrate the effectiveness of this correction method. Using one-year 2014 MPL measurements at the U.S. Department of Energy Atmospheric Radiation Measurement (ARM) North Slope of Alaska (NSA) site, the impact of the correction on the aerosol measurements is quantified. The relative error (RE, %) of attenuated backscattering ratio (ABR) without the afterpulse correction is 30% and 190% at the height of 1.00 km and 9.00 km (AGL), and the RE is larger for weaker aerosol signals (ABR<2). The RE of linear depolarization ratio (LDR), which is significantly higher than that of ABR for a given aerosol layer, is highly non-linear above 3.00 km, with a value of 300%-900% for weak aerosols (ABR<2) above 3.00 km. Therefore, the afterpulse correction is critical for the middle and upper tropospheric aerosol observations. We demonstrated that our afterpulse correction can provide reasonable particle depolarization ratio (PDR) to properly identify dust aerosols. The newly developed method can be applied to long-term MPL measurements to support aerosol and mixed-phase/ice cloud interaction study at the NSA site.

54 ENVIRONMENTAL SCIENCES↗
DOE OSTI2024

A research program to measure the lifetime of spin polarized fuel

The use of spin polarized fuel could increase the deuterium-tritium (D-T) fusion cross section by a factor of 1.5 and, owing to alpha heating, increase the fusion power by an even larger factor. Issues associated with the use of polarized fuel in a reactor are identified. Theoretically, nuclei remain polarized in a hot fusion plasma. The similarity between the Lorentz force law and the Bloch equations suggests polarization can be preserved despite the rich electromagnetic spectrum present in a magnetic fusion device. The most important depolarization mechanisms can be tested in existing devices. The use of polarized deuterium and 3 He in an experiment avoids the complexities of handling tritium, while encompassing the same nuclear reaction spin-physics, making it a useful proxy to study issues associated with full D-T implementation. 3 He fuel with 65% polarization can be prepared by permeating optically-pumped 3 He into a shell pellet. Dynamically polarized 7 Li-D pellets can achieve 70% vector polarization for the deuterium. Cryogenically-frozen pellets can be injected into fusion facilities by special injectors that minimize depolarizing field gradients. Alternatively, polarized nuclei could be injected as a neutral beam. Once injected, the lifetime of the polarized fuel is monitored through measurements of escaping charged fusion products. Multiple experimental scenarios to measure the polarization lifetime in the DIII-D tokamak and other magnetic-confinement facilities are discussed, followed by outstanding issues that warrant further study.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2026

Topology-Dependent Performance of Free-Space Photonic Quantum Networks Under Noise

Photonic quantum communication enables secure and high-fidelity information transfer beyond classical limits, with direct relevance to emerging quantum networks operating in free-space environments. While physical-layer models of depolarizing noise, Gamma–Gamma turbulence statistics, entanglement swapping, and decoy-state QKD security bounds are individually well established, prior work typically treats these components in isolation or under fixed network assumptions. In this work, we develop a unified topology-aware analytical framework that simultaneously integrates free-space optical link budgets, turbulence-induced visibility degradation, depolarizing qubit noise, multi-hop entanglement cascade dynamics, teleportation fidelity thresholds, CHSH nonlocality certification, and asymptotic decoy-state secret key rate bounds across star, mesh, and ring graph structures. Rather than introducing new physical channel models, we demonstrate that identical physical links exhibit fundamentally different end-to-end performance once embedded within different network topologies. Mesh architectures minimize visibility cascade through hop-count reduction but incur quadratic hardware scaling. Star topologies minimize link count but concentrate noise and synchronization overhead at the hub. Ring configurations offer linear hardware scaling with multiplicative fidelity degradation. The results establish topology as a first-order design parameter in near-term free-space quantum networks operating without full quantum repeater infrastructures. While motivated by distributed multi-agent architectures, the framework applies broadly to terrestrial, airborne, and satellite-assisted photonic quantum communication systems.

QKD↗
DOE OSTI2022

Evaluating cloud liquid detection against Cloudnet using cloud radar Doppler spectra in a pre-trained artificial neural network

Detection of liquid-containing cloud layers in thick mixed-phase clouds or multi-layer cloud situations from ground-based remote-sensing instruments still poses observational challenges, yet improvements are crucial since the existence of multi-layer liquid layers in mixed-phase cloud situations influences cloud radiative effects, cloud lifetime, and precipitation formation processes. Hydrometeor target classifications such as from Cloudnet that require a lidar signal for the classification of liquid are limited to the maximum height of lidar signal penetration and thus often lead to underestimations of liquid-containing cloud layers. Here we evaluate the Cloudnet liquid detection against the approach of Luke et al. (2010) which extracts morphological features in cloud-penetrating cloud radar Doppler spectra measurements in an artificial neural network (ANN) approach to classify liquid beyond full lidar signal attenuation based on the simulation of the two lidar parameters particle backscatter coefficient and particle depolarization ratio. We show that the ANN of Luke et al. (2010) which was trained under Arctic conditions can successfully be applied to observations at the mid-latitudes obtained during the 7-week-long ACCEPT field experiment in Cabauw, the Netherlands, in 2014. In a sensitivity study covering the whole duration of the ACCEPT campaign, different liquid-detection thresholds for ANN-predicted lidar variables are applied and evaluated against the Cloudnet target classification. Independent validation of the liquid mask from the standard Cloudnet target classification against the ANN-based technique is realized by comparisons to observations of microwave radiometer liquid-water path, ceilometer liquid-layer base altitude, and radiosonde relative humidity. In addition, a case-study comparison against the cloud feature mask detected by the space-borne lidar aboard the CALIPSO satellite is presented. Three conclusions were drawn from the investigation. First, it was found that the threshold selection criteria of liquid-related lidar backscatter and depolarization alone control the liquid detection considerably. Second, all threshold values used in the ANN framework were found to outperform the Cloudnet target classification for deep or multi-layer cloud situations where the lidar signal is fully attenuated within low liquid layers and the cloud radar is able to detect the microphysical fingerprint of liquid in higher cloud layers. Third, if lidar data are available, Cloudnet is at least as good as the ANN. The times when Cloudnet outperforms the ANN in liquid detections are often associated with situations where cloud dynamics smear the imprint of cloud microphysics on the radar Doppler spectra.

54 ENVIRONMENTAL SCIENCES↗
NASA NTRS1972

Calibration of radar data from Apollo 16 results, part X

Predictions of surface and near surface blockiness using earth based radar measurements were made. Two polarizations of the radar echoes were measured - polarized and depolarized. Particular attention was given to the depolarized echoes. North Ray and South Ray Craters and a 512-m diameter lunar crater in the Flamsteed Ring were used for the study.

Zisk, S. H.↗
NASA NTRS1973

On the measurement of Rayleigh scattering by gases at 6328A

The problem of laboratory measurements of Rayleigh scattering and depolarization ratio for atoms and molecules in the gaseous state is described. It is shown that, if the scattered radiation measurements are made at two angles, the normal depolarization ratio cannot be determined meaningfully. However, from scattering measurements, the Rayleigh scattering cross sections can be determined accurately. The measurements of Raleigh scattering from He, H2, Ar, O2, and N2 for unpolarized radiation at 6328A are reported and compared with similar measurements at 6943 and 1215.7A.

SHARDANAND↗
NASA NTRS1973

The influence of polarization on millimeter wave propagation through rain

The influence of polarization on millimeter wave propagation is investigated from both an experimental and a theoretical viewpoint. First, previous theoretical and experimental work relating to the attenuation and depolarization of millimeter waves by rainfall is discussed. Considerable detail is included in the literature review. Next, a theoretical model is developed to predict the cross polarization level during rainfall from the path average rain rate and the scattered field from a single raindrop. Finally, data from the VPI and SU depolarization experiment are presented as verification of the new model, and a comparison is made with other theories and experiments. Aspects of the new model are: (1) spherical rather than plane waves are assumed, (2) the average drop diameter is used rather than a drop size distribution, and (3) it is simple enough so that the effect which changing one or more parameters has on the crosspolarization level is easily seen.

Wiley, P. H.↗
NASA NTRS1976

One-man electrochemical air revitalization system evaluation

A program to evaluate the performance of a one man capacity, self contained electrochemical air revitalization system was successfully completed. The technology readiness of this concept was demonstrated by characterizing the performance of this one man system over wide ranges in cabin atmospheric conditions. The electrochemical air revitalization system consists of a water vapor electrolysis module to generate oxygen from water vapor in the cabin air, and an electrochemical depolarized carbon dioxide concentrator module to remove carbon dioxide from the cabin air. A control/monitor instrumentation package that uses the electrochemical depolarized concentrator module power generated to partially offset the water vapor electrolysis module power requirements and various structural fluid routing components are also part of the system. The system was designed to meet the one man metabolic oxygen generation and carbon dioxide removal requirements, thereby controlling cabin partial pressure of oxygen at 22 kN/sq m and cabin pressure of carbon dioxide at 400 N/sq m over a wide range in cabin air relative humidity conditions.

Schbert, F. H.↗
NASA NTRS1975

Lava flows in Mare Imbrium - An evaluation of anomalously low earth-based radar reflectivity

The surface of Mare Imbrium contains some of the most distinct red-blue colorimetric boundaries and depolarized 70-cm wavelength-reflectivity variations on the near side of the moon. The weakest levels of both 3.8-cm and 70-cm reflectivity within Imbrium are confined to spectrally blue regional mare surfaces that can be recognized as stratigraphically unique flow surfaces. Frequency distributions of the 70-cm polarized and depolarized radar-return power for five mare surfaces within the basin indicate that signal absorption, and probably ilmenite content, increases generally from the beginning of the Imbrium Period to the end of the Eratosthenian Period with slight reversal between the end of the Imbrium and beginning of the Eratosthenian. TiO2 calibrated radar-reflectivity curves can be utilized for lunar-maria geochemical mapping in the same manner as the TiO2 calibrated spectral-reflectivity curves of Charette et al. (1974).

Schaber, G. D.↗
NASA NTRS1975

The GSFC 20 and 30 GHz millimeter wave propagation experiment

The Goddard Space Flight Center Millimeter Wave Experiment (MWE) aboard ATS-6, designed to evaluate the propagation characteristics of earth-space communications links at 20 and 30 GHz, is outlined, and the major results to date are presented. The 20 and 30 GHz transmitters operate through spot beam or continental coverage antenna systems. The transmitted signals consist of 9 tones spaced out to 1440 MHz. A communications link 6 GHz up and 20 or 30 GHz down is provided. Attenuation ratio measurements between the 20 and 30 GHz links indicate values higher than those predicted. Clear sky scintillations have been observed with spectral components up to about 50 Hz. Observations of rain depolarization indicate that attenuation effects predominate over depolarization effects in frequency re-use communications systems in the 20 GHz region. Various methods of predicting path attenuation are under investigation.

Ippolito, L. J.↗
NASA NTRS1979

Accuracy of RGD approximation for computing light scattering properties of diffusing and motile bacteria

The study tests the accuracy of the Rayleigh-Gans-Debye (RGD) approximation against a rigorous scattering theory calculation for a simplified model of E. coli (about 1 micron in size) - a solid spheroid. A general procedure is formulated whereby the scattered field amplitude correlation function, for both polarized and depolarized contributions, can be computed for a collection of particles. An explicit formula is presented for the scattered intensity, both polarized and depolarized, for a collection of randomly diffusing or moving particles. Two specific cases for the intermediate scattering functions are considered: diffusing particles and freely moving particles with a Maxwellian speed distribution. The formalism is applied to microorganisms suspended in a liquid medium. Sensitivity studies revealed that for values of the relative index of refraction greater than 1.03, RGD could be in serious error in computing the intensity as well as correlation functions.

Kottarchyk, M.↗
NASA NTRS1979

Extended duration orbiter study: CO2 removal and water recovery

Two electrochemical depolarized carbon dioxide concentrator subsystems were evaluated against baseline lithium hydroxide for (1) the baseline orbiter when expanded to accommodate a crew of seven (mission option one), (2) an extended duration orbiter with a power extension package to reduce fuel cell expendables (mission option two), and (3) an extended duration orbiter with a full capability power module to eliminate fuel cell expendables (mission option three). The electrochemical depolarized carbon dioxide concentrator was also compared to the solid amine regenerable carbon dioxide removal concept. Water recovery is not required for Mission Option One since sufficient water is generated by the fuel cells. The vapor compression distillation subsystem was evaluated for mission option two and three only. Weight savings attainable using the vapor compression distillation subsystem for water recovery versus on-board water storage were determined. Combined carbon dioxide removal and water recovery was evaluated to determine the effect on regenerable carbon dioxide removal subsystem selection.

Marshall, R. D.↗