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At least 199 records · Page 11

Exploration Clinical Decision Support System: Medical Data Architecture

The Exploration Clinical Decision Support (ECDS) System project is intended to enhance the Exploration Medical Capability (ExMC) Element for extended duration, deep-space mission planning in HRP. A major development guideline is the Risk of "Adverse Health Outcomes & Decrements in Performance due to Limitations of In-flight Medical Conditions". ECDS attempts to mitigate that Risk by providing crew-specific health information, actionable insight, crew guidance and advice based on computational algorithmic analysis. The availability of inflight health diagnostic computational methods has been identified as an essential capability for human exploration missions. Inflight electronic health data sources are often heterogeneous, and thus may be isolated or not examined as an aggregate whole. The ECDS System objective provides both a data architecture that collects and manages disparate health data, and an active knowledge system that analyzes health evidence to deliver case-specific advice. A single, cohesive space-ready decision support capability that considers all exploration clinical measurements is not commercially available at present. Hence, this Task is a newly coordinated development effort by which ECDS and its supporting data infrastructure will demonstrate the feasibility of intelligent data mining and predictive modeling as a biomedical diagnostic support mechanism on manned exploration missions. The initial step towards ground and flight demonstrations has been the research and development of both image and clinical text-based computer-aided patient diagnosis. Human anatomical images displaying abnormal/pathological features have been annotated using controlled terminology templates, marked-up, and then stored in compliance with the AIM standard. These images have been filtered and disease characterized based on machine learning of semantic and quantitative feature vectors. The next phase will evaluate disease treatment response via quantitative linear dimension biomarkers that enable image content-based retrieval and criteria assessment. In addition, a data mining engine (DME) is applied to cross-sectional adult surveys for predicting occurrence of renal calculi, ranked by statistical significance of demographics and specific food ingestion. In addition to this precursor space flight algorithm training, the DME will utilize a feature-engineering capability for unstructured clinical text classification health discovery. The ECDS backbone is a proposed multi-tier modular architecture providing data messaging protocols, storage, management and real-time patient data access. Technology demonstrations and success metrics will be finalized in FY16.

Biomedical support↗

A connection between state-space and doubly coprime fractional representations

Explicit formulas for a doubly coprime fractional representation of the transfer function of a lumped LTI system are given in terms of a stabilizable and detectable state-space realization of the transfer function. These formulas allow existing computational algorithms to be utilized for the purpose of computing doubly coprime factorizations. Several additional implications of this result are briefly discussed, as are some immediate extensions and future research directions.

Nett, C. N.↗

Application of high-performance computing to numerical simulation of human movement

We have examined the feasibility of using massively-parallel and vector-processing supercomputers to solve large-scale optimization problems for human movement. Specifically, we compared the computational expense of determining the optimal controls for the single support phase of gait using a conventional serial machine (SGI Iris 4D25), a MIMD parallel machine (Intel iPSC/860), and a parallel-vector-processing machine (Cray Y-MP 8/864). With the human body modeled as a 14 degree-of-freedom linkage actuated by 46 musculotendinous units, computation of the optimal controls for gait could take up to 3 months of CPU time on the Iris. Both the Cray and the Intel are able to reduce this time to practical levels. The optimal solution for gait can be found with about 77 hours of CPU on the Cray and with about 88 hours of CPU on the Intel. Although the overall speeds of the Cray and the Intel were found to be similar, the unique capabilities of each machine are better suited to different portions of the computational algorithm used. The Intel was best suited to computing the derivatives of the performance criterion and the constraints whereas the Cray was best suited to parameter optimization of the controls. These results suggest that the ideal computer architecture for solving very large-scale optimal control problems is a hybrid system in which a vector-processing machine is integrated into the communication network of a MIMD parallel machine.

NASA Discipline Musculoskeletal↗

Recursive forward dynamics for multiple robot arms moving a common task object

Recursive forward dynamics algorithms are developed and presented for an arbitrary number of robot arms moving a commonly held object. The multiarm forward dynamics problem is to find the angular accelerations at the joints and the contact forces that the arms impart to the task object. The problem also involves finding the acceleration of this object. The multiarm forward dynamics solutions provide a thorough physical and mathematical understanding of the way several arms behave in response to a set of applied joint moments. Such an understanding simplifies and guides the subsequent control design and experimentation process. The forward dynamics algorithms also provide the necessary analytical foundation for conducting analysis and simulation studies. The multiarm algorithms are based on the filtering and smoothing approach recently advanced for single-arm dynamics, and they can be built up modularly from the single-arm algorithms. The algorithms compute recursively the joint angle accelerations, the contact forces, and the task-object accelerations. Algorithms are also developed to evaluate in closed form the linear transformations from the active joint moments to the joint angle accelerations, to the task object accelerations, and to the task-object contact forces. A possible computing architecture is presented as a precursor to a more complete investigation of the computational performance of the dynamics algorithms.

Rodriguez, Guillermo↗

A simple time-accurate turbomachinery algorithm with numerical solutions of an uneven blade count configuration

The present computer algorithm for the time-accurate flow analysis of rotating turbomachines is based on the finite-volume method and employs a high-resolution approximate Riemann solver for interface flux definitions and an implicit numerical scheme that possesses apparent unconditional stability. Block-block interfaces, including dynamic ones, are treated in such a way as to mimic interior block communication. The turbomachine configurations treated by way of illustration are 8-8-bladed and 11-9-bladed versions of a contrarotating unducted fan engine.

Janus, J. Mark↗

Recursive forward dynamics for multiple robot arms moving a common task object

Recursive forward dynamics algorithms are developed for an arbitrary number of robot arms moving a commonly held object. The multiarm forward dynamics problem is to find the angular accelerations at the joints and the contact forces that the arms impart to the task object. The problem also involves finding the acceleration of this object. The multiarm forward dynamics solutions provide a thorough physical and mathematical understanding of the way several arms behave in response to a set of applied joint moments. Such an understanding simplifies and guides the subsequent control design and experimentation process. The forward dynamics algorithms also provide the necessary analytical foundation for conducting analysis and simulation studies. The multiarm algorithms are based on the filtering and smoothing approach recently advanced for single-arm dynamics, and they can be built up modularly from the single-arm algorithms. The algorithms compute recursively the joint-angle accelerations, the contact forces, and the task-object accelerations. Algorithms are also developed to evaluate in closed form the linear transformations from the active joint moments to the joint-angle accelerations, to the task-object accelerations., and to the task-object contact forces. A possible computing architecture is presented as a precursor to a more complete investigation of the computational performance of the dynamics algorithms.

Rodriguez, G.↗

An algorithm for optimal single linear feature extraction from several Gaussian pattern classes

A computational algorithm is presented for the extraction of an optimal single linear feature from several Gaussian pattern classes. The algorithm minimizes the increase in the probability of misclassification in the transformed (feature) space. Numerical results on the application of this procedure to the remotely sensed data from the Purdue Cl flight line as well as LANDSAT data are presented. It was found that classification using the optimal single linear feature yielded a value for the probability of misclassification on the order of 30% less than that obtained by using the best single untransformed feature. Also, the optimal single linear feature gave performance results comparable to those obtained by using the two features which maximized the average divergence.

Starks, S. A.↗

Integration of symbolic and algorithmic hardware and software for the automation of space station subsystems

Traditional expert systems, such as diagnostic and training systems, interact with users only through a keyboard and screen, and are usually symbolic in nature. Expert systems that require access to data bases, complex simulations and real-time instrumentation have both symbolic as well as algorithmic computing needs. These needs could both be met using a general purpose workstation running both symbolic and algorithmic code, or separate, specialized computers networked together. The latter approach was chosen to implement TEXSYS, the thermal expert system, developed by NASA Ames Research Center in conjunction with Johnson Space Center to demonstrate the ability of an expert system to autonomously monitor the thermal control system of the space station. TEXSYS has been implemented on a Symbolics workstation, and will be linked to a microVAX computer that will control a thermal test bed. This paper will explore the integration options, and present several possible solutions.

Gregg, Hugh↗

Algorithm For Control Of Large Antenna

Alternative position-error feedback modes provided. Modern control theory basis for computer algorithm used to control two-axis positioning of large antenna. Algorithm - incorporated into software of real-time control computer - enables rapid intertarget positioning as well as precise tracking (using one of two optional position-feedback modes) without need of human operator intervention. Control system for one axis of two-axis azimuth/elevation control system embodied mostly in software based on advanced control theory. System has linear properties of classical linear feedback controller. Performance described by bandwidth and linear error coefficients.

Hill, Robert E.↗

Kinetics of cycle length dependence of ventricular repolarization: effect of autonomic blockade

INTRODUCTION: Beat-to-beat adaptation of ventricular repolarization duration to cardiac cycle length and autonomic activity has not been previously characterized in the spontaneously beating human heart. METHODS AND RESULTS: The ECG of 14 healthy subjects was recorded from the supine and upright positions. Autonomic blockade was accomplished by atropine and propranolol. RR and RT intervals were measured by a computer algorithm, and the impulse response (h) from RR to RT computed. In the supine position the maximal adjustment of the RT interval occurred in the first beat following a change in cycle length (hpeak = 17.8 +/- 1.6 msec/sec), but continued to be detectable for 3.8 seconds (2.9-4.7 sec). Propranolol attenuated the peak impulse response to 15.8 +/- 4.0 msec/sec (P = NS). In the standing position the peak impulse response was increased to 25.2 +/- 5.0 msec/sec (P = 0.004 vs supine), and the impulse response duration (hdur) shortened to 1.4 seconds (1.3-1.6). This was reversed by beta blockade (hpeak = 10.7 +/- 3.6 [P = 0.005 vs standing]; hdur = 5.5 sec [4.8-6.1]). Parasympathetic and combined autonomic blockade resulted in too little residual heart rate variability to estimate the impulse response accurately. The slope of the regression of delta RT and delta RR in the supine position was 0.0177 +/- 0.0016, which was closely correlated with the peak impulse response (r = 0.91). CONCLUSIONS: System identification techniques can assist in characterizing the cycle dependence of ventricular repolarization and may provide new insights into conditions associated with abnormal repolarization.

Clinical Trial↗

Conceptual designs and computer models of imaging radiometers for earth observations

An analytical model is developed based on engineering principles which can be used to predict the performance of spaceborne electro-optical remote sensors. Computer simulations and trade-off studies can be performed with this model to determine optimal sensor performance and design parameters. Computer algorithms were developed from which LOTUS spreadsheet macros were written. Computer simulations were performed to determine the performance characteristics and design parameters for the Moderate Resolution Imaging Spectrometer Nadir (MODIS-N) currently under development at NASA/Goddard Space Flight Center.

Montgomery, Harry E.↗

Dynamic interactions between hypersonic vehicle aerodynamics and propulsion system performance

Described here is the development of a flexible simulation model for scramjet hypersonic propulsion systems. The primary goal is determination of sensitivity of the thrust vector and other system parameters to angle of attack changes of the vehicle. Such information is crucial in design and analysis of control system performance for hypersonic vehicles. The code is also intended to be a key element in carrying out dynamic interaction studies involving the influence of vehicle vibrations on propulsion system/control system coupling and flight stability. Simple models are employed to represent the various processes comprising the propulsion system. A method of characteristics (MOC) approach is used to solve the forebody and external nozzle flow fields. This results in a very fast computational algorithm capable of carrying out the vast number of simulation computations needed in guidance, stability, and control studies. The three-dimensional fore- and aft body (nozzle) geometry is characterized by the centerline profiles as represented by a series of coordinate points and body cross-section curvature. The engine module geometry is represented by an adjustable vertical grid to accommodate variations of the field parameters throughout the inlet and combustor. The scramjet inlet is modeled as a two-dimensional supersonic flow containing adjustable sidewall wedges and multiple fuel injection struts. The inlet geometry including the sidewall wedge angles, the number of injection struts, their sweepback relative to the vehicle reference line, and strut cross-section are user selectable. Combustion is currently represented by a Rayleigh line calculation including corrections for variable gas properties; improved models are being developed for this important element of the propulsion flow field. The program generates (1) variation of thrust magnitude and direction with angle of attack, (2) pitching moment and line of action of the thrust vector, (3) pressure and temperature distributions throughout the system, and (4) performance parameters such as thrust coefficient, specific impulse, mass flow rates, and equivalence ratio. Preliminary results are in good agreement with available performance data for systems resembling the NASP vehicle configuration.

Flandro, G. A.↗

Transition Flight Control Room Automation

The Workstation Prototype Laboratory is currently working on a number of projects which we feel can have a direct impact on ground operations automation. These projects include: The Fuel Cell Monitoring System (FCMS), which will monitor and detect problems with the fuel cells on the Shuttle. FCMS will use a combination of rules (forward/backward) and multi-threaded procedures which run concurrently with the rules, to implement the malfunction algorithms of the EGIL flight controllers. The combination of rule based reasoning and procedural reasoning allows us to more easily map the malfunction algorithms into a real-time system implementation. A graphical computation language (AGCOMPL). AGCOMPL is an experimental prototype to determine the benefits and drawbacks of using a graphical language to design computations (algorithms) to work on Shuttle or Space Station telemetry and trajectory data. The design of a system which will allow a model of an electrical system, including telemetry sensors, to be configured on the screen graphically using previously defined electrical icons. This electrical model would then be used to generate rules and procedures for detecting malfunctions in the electrical components of the model. A generic message management (GMM) system. GMM is being designed as a message management system for real-time applications which send advisory messages to a user. The primary purpose of GMM is to reduce the risk of overloading a user with information when multiple failures occurs and in assisting the developer in devising an explanation facility. The emphasis of our work is to develop practical tools and techniques, while determining the feasibility of a given approach, including identification of appropriate software tools to support research, application and tool building activities.

Welborn, Curtis Ray↗

Algorithmic Extensions of Low-Dispersion Scheme and Modeling Effects for Acoustic Wave Simulation

Accurate computation of acoustic wave propagation may be more efficiently performed when their dispersion relations are considered. Consequently, computational algorithms which attempt to preserve these relations have been gaining popularity in recent years. In the present paper, the extensions to one such scheme are discussed. By solving the linearized, 2-D Euler and Navier-Stokes equations with such a method for the acoustic wave propagation, several issues were investigated. Among them were higher-order accuracy, choice of boundary conditions and differencing stencils, effects of viscosity, low-storage time integration, generalized curvilinear coordinates, periodic series, their reflections and interference patterns from a flat wall and scattering from a circular cylinder. The results were found to be promising en route to the aeroacoustic simulations of realistic engineering problems.

Kaushik, Dinesh K.↗

Advancing-Front Algorithm For Delaunay Triangulation

Efficient algorithm performs Delaunay triangulation to generate unstructured grids for use in computing two-dimensional flows. Once grid generated, one can optionally call upon additional subalgorithm that removes diagonal lines from quadrilateral cells nearly rectangular. Resulting approximately rectangular grid reduces cost per iteration of flow-computing algorithm.

Merriam, Marshal L.↗

Transition flight control room automation

The Workstation Prototype Laboratory is currently working on a number of projects which can have a direct impact on ground operations automation. These projects include: (1) The fuel cell monitoring system (FCMS), which will monitor and detect problems with the fuel cells on the shuttle. FCMS will use a combination of rules (forward/backward) and multithreaded procedures, which run concurrently with the rules, to implement the malfunction algorithms of the EGIL flight controllers. The combination of rule-based reasoning and procedural reasoning allows us to more easily map the malfunction algorithms into a real-time system implementation. (2) A graphical computation language (AGCOMPL) is an experimental prototype to determine the benefits and drawbacks of using a graphical language to design computations (algorithms) to work on shuttle or space station telemetry and trajectory data. (3) The design of a system will allow a model of an electrical system, including telemetry sensors, to be configured on the screen graphically using previously defined electrical icons. This electrical model would then be used to generate rules and procedures for detecting malfunctions in the electrical components of the model. (4) A generic message management (GMM) system is being designed for real-time applications as a message management system which sends advisory messages to a user. The primary purpose of GMM is to reduce the risk of overloading a user with information when multiple failures occur and to assist the developer in the devising an explanation facility. The emphasis of our work is to develop practical tools and techniques, including identification of appropriate software tools to support research, application, and tool building activities, while determining the feasibility of a given approach.

Welborn, Curtis Ray↗

Parallel Algorithm Solves Coupled Differential Equations

Numerical methods adapted to concurrent processing. Algorithm solves set of coupled partial differential equations by numerical integration. Adapted to run on hypercube computer, algorithm separates problem into smaller problems solved concurrently. Increase in computing speed with concurrent processing over that achievable with conventional sequential processing appreciable, especially for large problems.

Hayashi, A.↗