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SU-E-T-493: Influence of Filtered and Flatting Filter Free Photon Beam of 10 Megavolts Energy On Rapid Arc Radiotherapy Planning for Cervix Carcinoma

Purpose: Aim of this study is to determine the dosimetric influence of Filtered and Flatting Filter Free Photon Beam of 10 MV energy on RA planning for Ca. Cervix. Methods: CT data sets of eleven patients reported with carcinoma cervix were used for RA planning for 10MV -FFB and 10MV-FFFB. RA plans were generated using two full arcs.All RA plans were generated to deliver a dose of 50.4Gy in 28 fractions for PTV and ALARA for OAR’s. All plans were analysed for PTV Coverage, conformity Index, homogeneity index, dose to OAR’s, integral dose to normal tissue and total monitor units were studied. Results: DVH was used to evaluate RA plans for both 10MV-FFB and 10MV-FFFB photon beam. Planning results show a comparable PTV coverage for both energies. Results shows volume of PTV receiving prescription dose were 95.10+ 0.09% and 95.09 +0.11%, and volume of PTV receiving a dose of 107% is 0.45+0.96% and 5.25+8.9%, homogeneity index (HI) were 1.051+0.007 and 1.066+0.008, Conformity Index(CI) were 1.003+0.019 and 1.012+0.013, Mean Integral dose were 2.65+0.34 and 2.60+0.33(*10−5Gy.cm3) for 10MV-FFB and 10MV-FFFB respectively. 10MV-FB shows statistically significant (p<0.05) improvement in mean doses to bladder, rectum, bowel and mean total number of MU’s and also shows remarkable decrease in mean total no. of MU’s by 43.7% in comparison to 10MV-FFFB. There is statistically significant (p<0.05) difference found in CI and HI for 10MV-FB in comparison to 10MV -FFF beam. 10MV-FFFB shows statistically significant (p<0.05) for mean NTID and delivers 1.65 % less NTID in comparison to 10 MV- FB. Conclusion: 10MV-FB is superior to 10MV-FFFB for rapid arc planning in case of Cervix carcinomas, it offers better target coverage and OAR’s sparing, comparable mean Integral dose to normal tissues and 10 MV- FB also produced highly conformal and homogeneous dose distribution in comparison to 10MV-FFFB.

60 APPLIED LIFE SCIENCES↗

Single-neutron adding on $^{34}$S

For this work, single-neutron adding data was collected in order to determine the distribution of the single-neutron strength of the 0ƒ 7/2 , 1p 3/2 , 1p 1/2 and 0ƒ 5/2 orbitals outside of Z = 16, N = 18, 34 S. The 34 S(d,p) 35 S reaction has been measured at 8 MeV/u to investigate cross sections to excited states in 35 S. Outgoing proton yields and momenta were analyzed by the Super-Enge Split-Pole Spectrograph in conjunction with the CeBrA demonstrator located at the John D. Fox Laboratory at Florida State University. Angular distributions were compared with Distorted Wave Born Approximation calculations in order to extract single-neutron spectroscopic overlaps. Spectroscopic overlaps and strengths were determined for states in S up through 6 MeV in excitation energy. Each orbital was observed to have fragmented strength where a single level carried the majority. The single-neutron centroids of the 0ƒ 7/2 , 1p 3/2 , 1p 1/2 and 0ƒ 5/2 orbitals were determined to be 2360$^{+90}_{-40}$ keV, 3280$^{+80}_{-50}$ keV, 4780$^{+60}_{-40}$ keV, and ≳7500 keV, respectively. A previous discrepancy in the literature with respect to the distribution of the neutron 1p 1/2 strength was resolved. The integration of the normalized spectroscopic strengths, up to 5.1 MeV in excitation energy, revealed fully-vacant occupancies for the 0ƒ 7/2 , 1p 3/2 , and 1p 1/2 orbitals, as expected. The spacing in the single-neutron energies highlighted a reduction in the traditional N = 28 shell-gap, relative to both the 1p spin-orbit energy difference (N = 32) and the lower limit on the N = 34 shell spacing.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

VZr_BCC_SolidSolution_128atoms_VASP6

We performed density functional theory (DFT) calculations for body-centered-cubic (BCC) structures with 128 lattices sites of solid solution binary alloys vanadium-zirconium (V-Zr). The electronic structures of alloys have been calculated using Vienna Ab initio Simulation Package (VASP). Within this package the DFT approach is used to reduce many-body Schrodinger equation to set of single particle Kohn-Sham (KS) equations. The generalized electronic exchange-correlation functional is described by generalized gradient approximation with the Perdew-Burke-Ernzerhof parametrization. The electron-ion interactions is described by pseudopotentials developed within the plane-wave basis projector augmented-wave (PAW) approach \cite{PAW}. These pseudopotentials are available at the VASP portal (http://cms.mpi.univie.ac.at/vasp/). Our calculations have been run with the pseudopotentials treating s and p semi-core states as valence in case for the elements V and Zr. The electronic densities and potentials are expanded over plane-waves with energy cutoff of 350 eV. 2x2x2 k-mesh and normal precision were used. The alloys were modeled by supercell containing 128 randomly distributed atoms. At initial step the atoms occupy perfect bcc lattice cites. This initial structure was optimized until energy changes less than 1e-6 eV, while forces acting on atoms don't exceed 1e-2 eV/angstrom. The electron-ion interaction is described by PAW pseudopotentials. The calculations have been collected by sampling chemical compositions across the entire compositional range. The chemical compositions have been sampled by progressively changing the number of atoms per constituent by 4. For each chemical composition of binaries and ternaries, the first-principle calculations have been run for 100 randomized arrangements of the constituents on the BCC lattice sites. We collected data for a total of 3,100 randomized atomic structures over 31 chemical compositions.

36 MATERIALS SCIENCE↗

TaTi_BCC_SolidSolution_128atoms_VASP6

We performed density functional theory (DFT) calculations for body-centered-cubic (BCC) structures with 128 lattices sites of solid solution binary alloys tantalum-titanium (Ta-Ti). The electronic structures of alloys have been calculated using Vienna Ab initio Simulation Package (VASP). Within this package the DFT approach is used to reduce many-body Schrodinger equation to set of single particle Kohn-Sham (KS) equations. The generalized electronic exchange-correlation functional is described by generalized gradient approximation with the Perdew-Burke-Ernzerhof parametrization. The electron-ion interactions is described by pseudopotentials developed within the plane-wave basis projector augmented-wave (PAW) approach. These pseudopotentials are available at the VASP portal (http://cms.mpi.univie.ac.at/vasp/). Our calculations have been run with the pseudopotentials treating s and p semi-core states as valence in case for the elements Hf and Nb. The electronic densities and potentials are expanded over plane-waves with energy cutoff of 350 eV. 2x2x2 k-mesh and normal precision were used. The alloys were modeled by supercell containing 128 randomly distributed atoms. At initial step the atoms occupy perfect bcc lattice cites. This initial structure was optimized until energy changes less than 1e-6 eV, while forces acting on atoms don't exceed 1e-2 eV/angstrom. The electron-ion interaction is described by PAW pseudopotentials. The calculations have been collected by sampling chemical compositions across the entire compositional range. The chemical compositions have been sampled by progressively changing the number of atoms per constituent by 4. For each chemical composition of binaries and ternaries, the first-principle calculations have been run for 100 randomized arrangements of the constituents on the BCC lattice sites. We collected data for a total of 3,100 randomized atomic structures over 31 chemical compositions. The calculations have been collected on Air Force HPC11 cluster using the VASP 6.5.1. Additional methodology and file structure information is available in the dataset README.txt file.

36 MATERIALS SCIENCE↗

HfNb_BCC_SolidSolution_128atoms_VASP6

We performed density functional theory (DFT) calculations for body-centered-cubic (BCC) structures with 128 lattices sites of solid solution binary alloys hafnium-niobium (Hf-Nb). The electronic structures of alloys have been calculated using Vienna Ab initio Simulation Package (VASP). Within this package the DFT approach is used to reduce many-body Schrodinger equation to set of single particle Kohn-Sham (KS) equations. The generalized electronic exchange-correlation functional is described by generalized gradient approximation with the Perdew-Burke-Ernzerhof parametrization. The electron-ion interactions is described by pseudopotentials developed within the plane-wave basis projector augmented-wave (PAW) approach. These pseudopotentials are available at the VASP portal (http://cms.mpi.univie.ac.at/vasp/). Our calculations have been run with the pseudopotentials treating s and p semi-core states as valence in case for the elements Hf and Nb. The electronic densities and potentials are expanded over plane-waves with energy cutoff of 350 eV. 2x2x2 k-mesh and normal precision were used. The alloys were modeled by supercell containing 128 randomly distributed atoms. At initial step the atoms occupy perfect BCC lattice cites. This initial structure was optimized until energy changes less than 1e-6 eV, while forces acting on atoms don't exceed 1e-2 eV/angstrom. The electron-ion interaction is described by PAW pseudopotentials. The calculations have been collected by sampling chemical compositions across the entire compositional range. The chemical compositions have been sampled by progressively changing the number of atoms per constituent by 4. For each chemical composition of binaries and ternaries, the first-principle calculations have been run for 100 randomized arrangements of the constituents on the BCC lattice sites. We collected data for a total of 3,029 randomized atomic structures over 31 chemical compositions. Further methodological and structural information is contained in the dataset README.txt file.

36 MATERIALS SCIENCE↗

The EBEX Balloon-borne Experiment—Detectors and Readout

EBEX was a long-duration balloon-borne experiment to measure the polarization of the cosmic microwave background. The experiment had three frequency bands centered at 150, 250, and 410 GHz and was the first to use a kilopixel array of transition edge sensor bolometers aboard a balloon platform. We determine the design and characterization of the array and the readout system. From the lowest to highest frequency, the median measured detectors' average thermal conductances were 39, 53, and 63 pW/K, the medians of transition temperatures were 0.45, 0.48, and 0.47 K, and the medians of normal resistances were 1.9, 1.5, and 1.4 Ω; moreover, we give the measured distributions. With the exception of the thermal conductance at 150 GHz, all measured values are within 30% of their design. We measure median low-loop-gain time constants τ 0 = 88, 46, and 57 ms. Two measurements of bolometer absorption efficiency gave results consistent within 10% and showing high (~0.9) efficiency at 150 GHz and medium (~0.35 and ~0.25) efficiency at the two higher bands. We calculate a median total optical power absorbed of 3.6, 5.3, and 5.0 pW. EBEX pioneered the use of the digital version of the frequency domain multiplexing system. We multiplexed the bias and readout of 16 bolometers onto two wires. The median per-detector noise-equivalent temperatures are 400, 920, and 14,500 $\mu {{\rm{K}}}_{{\rm{cmb}}}\sqrt{{\rm{s}}}$. We compare these values to our preflight predictions and to a previous balloon payload. We report on the sources of excess noise and the path for a future payload to make full use of the balloon environment.

instrumentation: polarimeters↗

Whistler side-band growth due to nonlinear wave-particle interaction.

The distortion caused by a large-amplitude whistler (with wave normal parallel to the static magnetic field) on the energetic-electron velocity distribution of a predominantly cold magnetoplasma is derived analytically. Whistler test waves impressed on the perturbed magnetoplasma and within two narrow bands centered on the frequency of the original wave may experience large consecutive growth at the early stages of the wave-particle interaction if the unperturbed energetic-electron distribution satisfies two specified conditions. The relevance of these whistler side bands to magnetospheric phenomena is assessed; in particular, an identification of the onset of artificially stimulated emissions with the creation of whistler side bands gives good agreement with observations.

Brinca, A. L.↗

Photoballistics of volcanic jet activity at Stromboli, Italy

Two night eruptions of the volcano Stromboli were studied through 70-mm photography. Single-camera techniques were used. Particle sphericity, constant velocity in the frame, and radial symmetry were assumed. Properties of the particulate phase found through analysis include: particle size, velocity, total number of particles ejected, angular dispersion and distribution in the jet, time variation of particle size and apparent velocity distribution, averaged volume flux, and kinetic energy carried by the condensed phase. The frequency distributions of particle size and apparent velocities are found to be approximately log normal. The properties of the gas phase were inferred from the fact that it was the transporting medium for the condensed phase. Gas velocity and time variation, volume flux of gas, dynamic pressure, mass erupted, and density were estimated. A CO2-H2O mixture is possible for the observed eruptions. The flow was subsonic. Velocity variations may be explained by an organ pipe resonance. Particle collimation may be produced by a Magnus effect.

Chouet, B.↗

An implicit shock-fitting scheme for unsteady transonic flow computations

The alternating-direction implicit scheme developed by NASA Ames for unsteady transonic flows has been modified to include a shock-fitting algorithm as well as an analytically stretched coordinate system. The shock-fitting procedure treats shock waves as discontinuities normal to the free stream. Improvements in shock position and the unsteady pressure distributions are obtained by this modification. The various types of shock motion observed experimentally by Tijdeman are well simulated in calculations using the modified computational scheme. The method of detecting shock wave formation and the procedure for fitting a moving shock wave are illustrated. Results for a pulsating parabolic arc airfoil and for an NACA 64A006 airfoil with oscillating quarter-chord flap are presented and discussed.

Yu, N. J.↗

Multiple muons of conventional and exotic origin in DUMAND

A first summary of results from a theoretical analysis, based on hadron - muon cascade calculations, that yield relative intensities of very high energy multiple muons originating from ultra high energy interactions initiated by primary protons and iron nuclei in the atmosphere, under consideration of normal as well as direct and exotic production channels is presented. Lateral density distributions and target diagrams will be presented which show that only very large detectors, such as DUMAND, will be able to record multiple muons of conventional origin reliably. This, however, is a prerequisite for any primary mass determination based on multiple muon data.

Grieder, K. F.↗

The calculated influence of atmospheric conditions on solar cell ISC under direct and global solar irradiances

Calculations of the influence of atmospheric conditions on solar cell short-circuit current (Isc) are made using a recently developed computer model for solar spectral irradiance distribution. The results isolate the dependence of Isc on changes in the spectral irradiance distribution without the direct influence of the total irradiance level. The calculated direct normal irradiance and percent diffuse irradiance are given as a reference to indicate the expected irradiance levels. This method can be applied to the calibration of photovoltaic reference cells. Graphic examples are provided for amorphous silicon and monocrystalline silicon solar cells under direct normal and global normal solar irradiances.

Mueller, Robert L.↗

Application of strain gages to measure adhesive strains through the thickness of an adhesively-bonded stiffened strip

The purpose of the study is to measure the through-the-thickness strain distribution in an adhesively bonded stiffened strip subject to four-point bending and to compare the distribution with predicted results. Small-strain gages are used for measuring the normal strain in the adhesive layer of the strip. A total of 16 120-ohm encapsulated strain gages were mounted on the adhesive layer, and the specimen was loaded quasi-statistically and never to failure. Both the experimental and analytical results show good correlation and, in particular, a high strain gradient acting near the edge of the adhesive layer.

Lopez, O. F.↗

Wing plan forms for high-speed flight

It is pointed out that, in the case of an airfoil of infinite aspect ratio moving at an angle of sideslip, the pressure distribution is determined solely by that component of the motion in a direction normal to the leading edge. It follows that the attachment of plane waves to the airfoil at near-sonic or supersonic speeds (Ackeret theory) may be avoided and the pressure drag may be reduced by the use of plan forms in which the angle of sweepback is greater than the Mach angle. The analysis indicates that for aerodynamic efficiency, wings designed for flight at supersonic speeds should be swept back at an angle greater than the Mach angle, and the angle of sweepback should be such that the component of velocity normal to the leading edge is less than the critical speed of the airfoil sections. This principle may also be applied to wings designed for subsonic speeds near the speed of sound, for which the induced velocities resulting from the thickness might otherwise be sufficiently great to cause shock waves.

Jones, Robert J↗

Hybrid simulations of thin current sheets

A one-dimensional, hybrid simulation code is used to study current sheets with a nonzero normal magnetic field B(sub z) and a dawn-to-dusk electric field E(sub y). Such configurations are dependent upon only two parameters: we use the normalized normal magnetic field B-normalized (sub z) = B(sub z)/(4(pi)(n(sub b)) (v(exp 2 sub T))(exp 1/2) and normalized electric field V-normalized (sub D) = (1/V(sub T)(cE(sub y)/B(sub z)), where V(sub T) is the thermal velocity of ions prior to their interaction with the current sheet and n(sub b) is the number density outside the current sheet (at the simulation boundary). A third parameter that is relevant to the motion of particles in current sheets is kappa(sub A), the value of kappa = (R(sub min)/rho(sub max))(exp 1/2) for particles of average energy. We find that if either B-normalized (sub z) is close to or greater than 1, or if kappa(sub A) is close to 1, a rotational mode develops in which the z = 0 current rotates with the ion sense about the normal magnetic field, while for small values of both B-normalized (sub z) or kappa(sub A), the configuration is quasi-steady. To achieve values of kappa(sub A) of the order of or larger than 1, we decrease the value of V-normalized (sub D) uniformly. We find that the magnetic field fluctuations and particle distribution functions are similar in many respects to what was observed in the day 240, 1986, Active Magnetospheric Particle Tracer Explorer (AMPTE)/CCE current disruption event, an event that appears to be located at the site of initiation of current disruption and related particle energization.

Burkhart, G. R.↗

Scanning micro-Hall probe mapping of magnetic flux distributions and current densities in YBa2Cu3O7 thin films

Mapping of the magnetic flux density B(sub z) (perpendicular to the film plane) for a YBa2Cu3O7 thin-film sample was carried out using a scanning micro-Hall probe. The sheet magnetization and sheet current densities were calculated from the B(sub z) distributions. From the known sheet magnetization, the tangential (B(sub x,y)) and normal components of the flux density B were calculated in the vicinity of the film. It was found that the sheet current density was mostly determined by 2B(sub x,y)/d, where d is the film thickness. The evolution of flux penetration as a function of applied field will be shown.

Xing, W.↗

Inverse sequential procedures for the monitoring of time series

When one or more new values are added to a developing time series, they change its descriptive parameters (mean, variance, trend, coherence). A 'change index (CI)' is developed as a quantitative indicator that the changed parameters remain compatible with the existing 'base' data. CI formulate are derived, in terms of normalized likelihood ratios, for small samples from Poisson, Gaussian, and Chi-Square distributions, and for regression coefficients measuring linear or exponential trends. A substantial parameter change creates a rapid or abrupt CI decrease which persists when the length of the bases is changed. Except for a special Gaussian case, the CI has no simple explicit regions for tests of hypotheses. However, its design ensures that the series sampled need not conform strictly to the distribution form assumed for the parameter estimates. The use of the CI is illustrated with both constructed and observed data samples, processed with a Fortran code 'Sequitor'.

Radok, Uwe↗

Heat-Transfer Measurements on the Apexes of Two 60 deg Sweptback Delta Wings (Panel Semiapex Angle of 30 deg) Having 0 deg and 45 deg Dihedral at a Mach Number of 4.95

An experimental investigation was conducted to evaluate the heat-transfer rates at the apex of two 60 degree sweptback delta wings (panel semi-apex angle of 30 degrees) having cylindrical leading edges and 0 degrees and 45 degree positive dihedral. The models tested might correspond to the first several feet of a hypersonic reentry vehicle. The tests were conducted at a Mach number of 4.95 and a stagnation temperature of 400 F. nominal test-section unit Reynolds numbers varied from 2 x 10(exp 6) to 12 x 10(exp 6) per foot. The results of the investigation indicated that the laminar heat-transfer distributions (ratio of local to stagnation-line heating rate) about the models normal to the leading edges were in close agreement with two-dimensional blunt-body theory. The three-dimensional stagnation point heat-transfer rate on the 0 degree dihedral model was in excellent agreement with theory and the stagnation-line heat transfer on the straight portion of the leading edge of both models approached a constant level 12 percent above the theoretical stagnation-line level on an isolated swept infinite cylinder. When the heating rates on the 45 degree dihedral model (planform sweep of 69.3 degree) were compared with those on the 0 degree dihedral model (planform sweep of 60 degrees) at equal angles of attack and equal lifts greater than zero, the stagnation-line heating rates on the 45 degrees dihedral model were, in general, considerably lower as a result of the difference in effective sweeps of the leading edges. On the wing panels inboard from the stagnation lines, the differences in heating were very small. The stagnation-line heat-transfer variation with angle of attack, the shift in stagnation-line location, and the reduction in stagnation-line heat transfer resulting from the increase in effective sweep when positive dihedral is incorporated into a constant-panel 0 degree dihedral wing, all agreed with the results of a theoretical study made of highly swept delta wings with large positive dihedral.

Gunn, Charles R.↗

Microarray analysis identifies Salmonella genes belonging to the low-shear modeled microgravity regulon

The low-shear environment of optimized rotation suspension culture allows both eukaryotic and prokaryotic cells to assume physiologically relevant phenotypes that have led to significant advances in fundamental investigations of medical and biological importance. This culture environment has also been used to model microgravity for ground-based studies regarding the impact of space flight on eukaryotic and prokaryotic physiology. We have previously demonstrated that low-shear modeled microgravity (LSMMG) under optimized rotation suspension culture is a novel environmental signal that regulates the virulence, stress resistance, and protein expression levels of Salmonella enterica serovar Typhimurium. However, the mechanisms used by the cells of any species, including Salmonella, to sense and respond to LSMMG and identities of the genes involved are unknown. In this study, we used DNA microarrays to elucidate the global transcriptional response of Salmonella to LSMMG. When compared with identical growth conditions under normal gravity (1 x g), LSMMG differentially regulated the expression of 163 genes distributed throughout the chromosome, representing functionally diverse groups including transcriptional regulators, virulence factors, lipopolysaccharide biosynthetic enzymes, iron-utilization enzymes, and proteins of unknown function. Many of the LSMMG-regulated genes were organized in clusters or operons. The microarray results were further validated by RT-PCR and phenotypic analyses, and they indicate that the ferric uptake regulator is involved in the LSMMG response. The results provide important insight about the Salmonella LSMMG response and could provide clues for the functioning of known Salmonella virulence systems or the identification of uncharacterized bacterial virulence strategies.

Non-NASA Center↗

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