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At least 1,801 records · Page 100

Building flexible real-time systems using the Flex language

The design and implementation of a real-time programming language called Flex, which is a derivative of C++, are presented. It is shown how different types of timing requirements might be expressed and enforced in Flex, how they might be fulfilled in a flexible way using different program models, and how the programming environment can help in making binding and scheduling decisions. The timing constraint primitives in Flex are easy to use yet powerful enough to define both independent and relative timing constraints. Program models like imprecise computation and performance polymorphism can carry out flexible real-time programs. In addition, programmers can use a performance measurement tool that produces statistically correct timing models to predict the expected execution time of a program and to help make binding decisions. A real-time programming environment is also presented.

Kenny, Kevin B.↗

The Emphasis of Design Patterns in Expressing Expert Knowledge From A Technical Solution – A Framework for Continued Research

Digital Engineering is a transformative strategy that leverages an integrated model-based approach to improve communication, decision making, design understanding, and acquisition efficiency of system development. As modern systems are derived from pre-existing systems, harvesting expert knowledge from proven systems in a useful, model-based way will reduce the experiential learning and cognition required for new system development, contributing to a Digital Engineering transformation. Motivated by performance gains observed during a multi-year, sequential development activity, this survey reviews knowledge, architecture, and pattern literature to establish a framework for research of architectural methods for expert knowledge identification and description using Model Based System Engineering. The multi-year sequential development activity is offered as the experimental system of interest for this research. This work aims to enable a digital engineering strategy that improves concept phase decision making, accelerates knowledge acquisition from lessons learned repositories, and eases the burden of generational knowledge loss.

Lithium Ion↗

Semi-supervised Learning of Dynamical Systems with Neural Ordinary Differential Equations: A Teacher-Student Model Approach

Modeling dynamical systems is crucial for a wide range of tasks, but it remains challenging due to complex nonlinear dynamics, limited observations, or lack of prior knowledge. Recently, data-driven approaches such as Neural Ordinary Differential Equations (NODE) have shown promising results by leveraging the expressive power of neural networks to model unknown dynamics. However, these approaches often suffer from limited labeled training data, leading to poor generalization and suboptimal predictions. On the other hand, semi-supervised algorithms can utilize abundant unlabeled data and have demonstrated good performance in classification and regression tasks. We propose TS-NODE, the first semi-supervised approach to modeling dynamical systems with NODE. TS-NODE explores cheaply generated synthetic pseudo rollouts to broaden exploration in the state space and to tackle the challenges brought by lack of ground-truth system data under a teacher-student model. TS-NODE employs an unified optimization framework that corrects the teacher model based on the student's feedback while mitigating the potential false system dynamics present in pseudo rollouts. TS-NODE demonstrates significant performance improvements over a baseline Neural ODE model on multiple dynamical system modeling tasks.

Wang, Yu↗

Isoform-specific functions of synaptopodin-2 variants in cytoskeleton stabilization and autophagy regulation in muscle under mechanical stress

Highlights: • Muscle cells express different synaptopodin-2 isoforms with individual functions. • Reduced SYNPO2 expression results in enhanced vulnerability of myofibrils. • SYNPO2e recruites BAG3 to mechanically stressed myofibrillar areas. • SYNPO2 is an organizer and regulator of BAG3-containing proteostasis systems. • BAG3 forms functionally distinct protein complexes with different SYNPO2 isoforms. Protein homeostasis (proteostasis) in multicellular organisms depends on the maintenance of force-bearing and force-generating cellular structures. Within myofibrillar Z-discs of striated muscle, isoforms of synaptopodin-2 (SYNPO2/myopodin) act as adapter proteins that are engaged in proteostasis of the actin-crosslinking protein filamin C (FLNc) under mechanical stress. SYNPO2 directly binds F-actin, FLNc and α-actinin and thus contributes to the architectural features of the actin cytoskeleton. By its association with autophagy mediating proteins, i.e. BAG3 and VPS18, SYNPO2 is also engaged in protein quality control and helps to target mechanical unfolded and damaged FLNc for degradation. Here we show that deficiency of all SYNPO2-isoforms in myotubes leads to decreased myofibrillar stability and deregulated autophagy under mechanical stress. In addition, isoform-specific proteostasis functions were revealed. The PDZ-domain containing variant SYNPO2b and the shorter, PDZ-less isoform SYNPO2e both localize to Z-discs. Yet, SYNPO2e is less stably associated with the Z-disc than SYNPO2b, and is dynamically transferred into FLNc-containing myofibrillar lesions under mechanical stress. SYNPO2e also recruits BAG3 into these lesions via interaction with the WW domain of BAG3. Our data provide evidence for a role of myofibrillar lesions as a transient quality control compartment essential to prevent and repair contraction-induced myofibril damage in muscle and indicate an important coordinating activity for SYNPO2 therein.

60 APPLIED LIFE SCIENCES↗

Biocontainment of Genetically Engineered Algae

Algae (including eukaryotic microalgae and cyanobacteria) have been genetically engineered to convert light and carbon dioxide to many industrially and commercially relevant chemicals including biofuels, materials, and nutritional products. At industrial scale, genetically engineered algae may be cultivated outdoors in open ponds or in closed photobioreactors. In either case, industry would need to address a potential risk of the release of the engineered algae into the natural environment, resulting in potential negative impacts to the environment. Genetic biocontainment strategies are therefore under development to reduce the probability that these engineered bacteria can survive outside of the laboratory or industrial setting. These include active strategies that aim to kill the escaped cells by expression of toxic proteins, and passive strategies that use knockouts of native genes to reduce fitness outside of the controlled environment of labs and industrial cultivation systems. Several biocontainment strategies have demonstrated escape frequencies below detection limits. However, they have typically done so in carefully controlled experiments which may fail to capture mechanisms of escape that may arise in the more complex natural environment. The selection of biocontainment strategies that can effectively kill cells outside the lab, while maintaining maximum productivity inside the lab and without the need for relatively expensive chemicals will benefit from further attention.

59 BASIC BIOLOGICAL SCIENCES↗

Kinetics of the reaction of nitric oxide with hydrogen

The reaction of nitric oxide with hydrogen has been studied in the temperature range 2400-4500 K using a shock-tube technique. Mixtures of NO and H2 diluted in argon or krypton were heated by incident shock waves, and the infrared emission from the fundamental vibration-rotation band of NO at 5.3 microns was used to monitor the time-varying NO concentration. The decomposition of nitric oxide behind the shock was found to be modeled well by a fifteen-reaction system. A principal result of the study was the determination of the rate constant k1 for the reaction H + NO yields N + OH, which may be the rate-limiting step for NO removal in some combustion systems. Experimental values of k1 were obtained for each test through comparisons of measured and numerically predicted NO profiles. The data are fit closely by the expression k1 = 1.34 times 10 to the fourteenth power exp(-49 200/RT) cu cm/mole-sec. These data appear to be the first available for this rate constant.

Flower, W. L.↗

Cost comparison of competing local distribution systems for communication satellite traffic

The boundaries of market areas which favor various means for distributing communications satellite traffic are considered. The distribution methods considered are: control Earth station with cable access, rooftop Earth stations, Earth station with radio access, and various combinations of these methods. The least cost system for a hypothetical region described by number of users and the average cable access mileage is discussed. The region is characterized by a function which expresses the distribution of users. The results indicate that the least cost distribution is central Earth station with cable access for medium to high density areas of a region combined with rooftop Earth stations or (for higher volumes) radio access for remote users.

Dopfel, F. E.↗

Closed-form solutions for feedback control with terminal constraints

The problem of closed-loop control of maneuvers between two states for linear dynamical systems, subject to an arbitrarily specified terminal state, is considered. The feedback controller design is based on finite-time quadratic regulator theory. Closed-form expressions for the optimal control law are developed. Solutions are presented for both conventional and smoothed control profiles with fixed and/or free end condition problems. In the maneuvers using control-rate penalties, smooth profiles are generated throughout the maneuvers, in the sense that the initial condition jump discontinuities have been eliminated. Several examples involving large-angle maneuvers of a spacecraft are demonstrated. Results include control maneuvers from one state to another such as rest to rest and spin to rest, which effectively justify the solutions developed in this paper.

Juang, J.-N.↗

Neural control of muscle

Cholinergic innervation regulates the physiological and biochemical properties of skeletal muscle. The mechanisms that appear to be involved in this regulation include soluble, neurally-derived polypeptides, transmitter-evoked muscle activity and the neurotransmitter, acetylcholine, itself. Despite extensive research, the interacting neural mechanisms that control such macromolecules as acetylcholinesterase, the acetylcholine receptor and glucose 6-phosphate dehydrogenase remain unclear. It may be that more simplified in vitro model systems coupled with recent dramatic advances in the molecular biology of neurally-regulated proteins will begin to allow researchers to unravel the mechanisms controlling the expression and maintenance of these macromolecules.

Max, S. R.↗

Manipulation and Display of Panel-Method Geometry

GEOM manipulates and displays any geometry data expressed in Hess format. Provides user with capability to manipulate, modify, and view such geometric configurations interactively. GEOM program and the PAGMS data-base management system written in FORTRAN IV.

Hall, J. F.↗

Compton-heated winds and coronae above accretion disks. II - Instability and oscillations

The stability and evolution of windy accretion disks is investigated in detail. The basic disk evolution equations are briefly recapitulated, and an idealized analytic treatment of the wind and viscosity is used to show that steady disk flow is indeed unstable for sufficiently large ratio of the mass loss rate in the wind to the central accretion rate. Numerical solutions for a more realistic and appropriate expression for the mass loss rate and the standard ad hoc alpha model prescription for the viscosity are presented. The application of these results to real systems with Compton-heated winds is discussed, and a general formula for the oscillation period is given. The prediction is compared with observed periodic behavior of Galactic X-ray sources and AGNs.

Shields, G. A.↗

A language comparison for scientific computing on MIMD architectures

Choleski's method for solving banded symmetric, positive definite systems is implemented on a multiprocessor computer using three FORTRAN based parallel programming languages, the Force, PISCES and Concurrent FORTRAN. The capabilities of the language for expressing parallelism and their user friendliness are discussed, including readability of the code, debugging assistance offered, and expressiveness of the languages. The performance of the different implementations is compared. It is argued that PISCES, using the Force for medium-grained parallelism, is the appropriate choice for programming Choleski's method on the multiprocessor computer, Flex/32.

Jones, Mark T.↗

Connecting coherent structures and strange attractors

A concept of turbulence derived from nonlinear dynamical systems theory suggests that turbulent solutions to the Navier-Stokes equations are restricted to strange attractors, and, by implication, that turbulent phenomenology must find some expression or source in the structure of these mathematical objects. Examples and discussions are presented to link coherent structures to some of the commonly known characteristics of strange attractors. Basic to this link is a geometric interpretation of conditional sampling techniques employed to educe coherent structures that offers an explanation for their appearance in measurements as well as their size.

Keefe, Laurence R.↗

Ranging performance of satellite laser altimeters

Topographic mapping of the earth, moon and planets can be accomplished with high resolution and accuracy using satellite laser altimeters. These systems employ nanosecond laser pulses and microradian beam divergences to achieve submeter vertical range resolution from orbital altitudes of several hundred kilometers. Here, we develop detailed expressions for the range and pulse width measurement accuracies and use the results to evaluate the ranging performances of several satellite laser altimeters currently under development by NASA for launch during the next decade. Our analysis includes the effects of the target surface characteristics, spacecraft pointing jitter and waveform digitizer characteristics. The results show that ranging accuracy is critically dependent on the pointing accuracy and stability of the altimeter especially over high relief terrain where surface slopes are large. At typical orbital altitudes of several hundred kilometers, single-shot accuracies of a few centimeters can be achieved only when the pointing jitter is on the order of 10 mu rad or less.

Gardner, Chester S.↗

TUNS/TCIS information model/process model

An Information Model is comprised of graphical and textual notation suitable for describing and defining the problem domain - in our case, TUNS or TCIS. The model focuses on the real world under study. It identifies what is in the problem and organizes the data into a formal structure for documentation and communication purposes. The Information Model is composed of an Entity Relationship Diagram (ERD) and a Data Dictionary component. The combination of these components provide an easy to understand methodology for expressing the entities in the problem space, the relationships between entities and the characteristics (attributes) of the entities. This approach is the first step in information system development. The Information Model identifies the complete set of data elements processed by TUNS. This representation provides a conceptual view of TUNS from the perspective of entities, data, and relationships. The Information Model reflects the business practices and real-world entities that users must deal with.

Wilson, James↗

Flight Investigation of Control-stick Vibration of the YG-1B Autogiro

As a preliminary step in an investigation of control-stick vibration in direct-control autogiros, the periodic variations in the moments transmitted through the control system of a YG-1B autogiro were recorded in flight. The results of the measurements are presented in the form of coefficients of Fourier series expressing the varying part of the lateral and the longitudinal moments acting between rotor and fuselage at the control trunnions. The most important component of the variation in stick force was found to have frequency of three times the rotor speed and an amplitude that rose from negligible values at tip-speed ratio below 0.20 to +/-5.2 pounds longitudinally and +/-3.2 pounds laterally at tip-speed ratios of 0.35. Variations in stick force at all other frequencies were small in comparison with those at three times the rotor speed.

Bailey, F J , Jr↗

Study of the supersonic propeller

In this paper a propeller having all sections operating at supersonic speeds is designated a supersonic propeller regardless of flight speed. Analyses assume subsonic flight speeds but very high rotational speeds. A very elementary analysis of the efficiency of a jet-propeller system is presented. A propeller analysis based on conventional vortex blade element theory is presented and reduced to a single point method which leads to an expression for optimum advance ratio in terms of hub-tip diameter ratio and airfoil fineness ratio. An expression for propeller efficiency in terms of advance ratio, hub-tip diameter ratio, and airfoil thickness ratio is also presented. Use is made of theoretical airfoil characteristics at supersonic speeds. A study of blade section interference, blade shock and expansion fields, at supersonic section speeds is presented. An example taken indicates that an efficiency of seventy percent can be obtained with a propeller having a tip Mach number of 2.3.

PROPELLERS, SUPERSONIC↗

REQUEST: A Recursive QUEST Algorithm for Sequential Attitude Determination

In order to find the attitude of a spacecraft with respect to a reference coordinate system, vector measurements are taken. The vectors are pairs of measurements of the same generalized vector, taken in the spacecraft body coordinates, as well as in the reference coordinate system. We are interested in finding the best estimate of the transformation between these coordinate system.s The algorithm called QUEST yields that estimate where attitude is expressed by a quarternion. Quest is an efficient algorithm which provides a least squares fit of the quaternion of rotation to the vector measurements. Quest however, is a single time point (single frame) batch algorithm, thus measurements that were taken at previous time points are discarded. The algorithm presented in this work provides a recursive routine which considers all past measurements. The algorithm is based on on the fact that the, so called, K matrix, one of whose eigenvectors is the sought quaternion, is linerly related to the measured pairs, and on the ability to propagate K. The extraction of the appropriate eigenvector is done according to the classical QUEST algorithm. This stage, however, can be eliminated, and the computation simplified, if a standard eigenvalue-eigenvector solver algorithm is used. The development of the recursive algorithm is presented and illustrated via a numerical example.

Bar-Itzhack, Itzhack Y.↗

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