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At least 181 records · Page 10

Space Life Sciences Research: The Importance of Long-Term Space Experiments

This report focuses on the scientific importance of long-term space experiments for the advancement of biological science and the benefit of humankind. It includes a collection of papers that explore the scientific potential provided by the capability to manipulate organisms by removing a force that has been instrumental in the evolution and development of all organisms. Further, it provides the scientific justification for why the long-term space exposure that can be provided by a space station is essential to conduct significant research.

Source record↗

Experimental and Computational Mechanisms that Govern Long-Term Stability of CO 2 -Adsorbed ZIF-8-Based Porous Liquids

Porous liquids (PLs) based on the zeolitic imidazole framework ZIF-8 are attractive systems for carbon capture since the hydrophobic ZIF framework can be solvated in aqueous solvent systems without porous host degradation. However, solid ZIF-8 is known to degrade when exposed to CO 2 in wet environments, and therefore the long-term stability of ZIF-8-based PLs is unknown. Here, through aging experiments, the long-term stability of a ZIF-8 PL formed using the water, ethylene glycol, and 2-methylimidazole solvent system was systematically examined, and the mechanisms of degradation were elucidated. The PL was found to be stable for several weeks, with no ZIF framework degradation observed after aging in N 2 or air. However, for PLs aged in a CO 2 atmosphere, formation of a secondary phase occurred within 1 day from the degradation of the ZIF-8 framework. From the computational and structural evaluation of the effects of CO 2 on the PL solvent mixture, it was identified that the basic environment of the PL caused ethylene glycol to react with CO 2 forming carbonate species. These carbonate species further react within the PL to degrade ZIF-8. The mechanisms governing this process involves a multistep pathway for PL degradation and lays out a long-term evaluation strategy of PLs for carbon capture. Additionally, it clearly demonstrates the need to examine the reactivity and aging properties of all components in these complex PL systems in order to fully assess their stabilities and lifetimes.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Long-term effects of low-dose proton radiation on immunity in mice: shielded vs. unshielded

BACKGROUND: Outside the protection of the terrestrial environment, astronauts on any long-term missions will unavoidably be exposed to fields of charged particle radiation dominated by protons. These fields and their biological risks are modified in complex ways by the presence of protective shielding. METHODS: To examine the long-term effects of space-like proton exposures on immune status, we treated female C57BL/6 mice with 3 or 4 Gy of 250 MeV monoenergetic protons or the complex space-like radiation field produced after 250 MeV protons are transported through 15 g x cm(-2) aluminum shielding. The animals were euthanized 122 d post-irradiation and lymphocyte phenotypes, hematological parameters, and lymphocyte blastogenesis were characterized. RESULTS: There were significant dose-dependent decreases in macrophage, CD3+/CD8+ T, NK, platelet, and red blood cell populations, as well as low hematocrit and hemoglobin levels. In contrast, dose-dependent increases in spontaneous, but not mitogen-induced, blastogenesis were noted. The differences in dose composition between pristine and shielded proton fields did not lead to significant effects in most measures, but did result in significant changes in monocyte and macrophage populations and spontaneous blastogenesis in the spleen. CONCLUSIONS: The data indicate that whole body exposure to proton radiation at doses of the order of large solar particle events or clinical treatment fractions may have long-term effects on immune system status.

NASA Discipline Radiation Health↗

Implications of Version 8 TOMS and SBUV Data for Long-Term Trend Analysis

Total ozone data from the Total Ozone Mapping Spectrometer (TOMS) and profile/total ozone data from the Solar Backscatter Ultraviolet (SBUV; SBW/2) series of instruments have recently been reprocessed using new retrieval algorithms (referred to as Version 8 for both) and updated calibrations. In this paper, we incorporate the Version 8 data into a TOMS/SBW merged total ozone data set and an S B W merged profile ozone data set. The Total Merged Ozone Data (Total MOD) combines data from multiple TOMS and SBW instruments to form an internally consistent global data set with virtually complete time coverage from October 1978 through December 2003. Calibration differences between instruments are accounted for using external adjustments based on instrument intercomparisons during overlap periods. Previous results showed errors due to aerosol loading and sea glint are significantly reduced in the V8 TOMS retrievals. Using SBW as a transfer standard, calibration differences between V8 Nimbus 7 and Earth Probe TOMS data are approx. 1.3%, suggesting small errors in calibration remain. We will present updated total ozone long-term trends based on the Version 8 data. The Profile Merged Ozone Data (Profile MOD) data set is constructed using data from the SBUV series of instruments. In previous versions, SAGE data were used to establish the long-term external calibration of the combined data set. The SBW Version 8 we assess the V8 profile data through comparisons with SAGE and between SBW instruments in overlap periods. We then construct a consistently-calibrated long term time series. Updated zonal mean trends as a function of altitude and season from the new profile data set will be shown, and uncertainties in determining the best long-term calibration will be discussed.

Frith, Stacey M.↗

Neonatal respiratory support strategies—short and long-term respiratory outcomes

Mechanical ventilation (MV), although life-saving, is associated with chronic respiratory morbidity in both preterm and term born infants. New ventilation modes have been developed with the aim of minimising lung injury. These include invasive and non-invasive respiratory support strategies, techniques for less invasive surfactant administration (LISA) and closed-loop automated oxygen control (CLAC) systems. Increasingly, newborn infants with signs of respiratory distress are stabilised on continuous positive airway pressure (CPAP) and receive LISA. Early CPAP when compared to mechanical ventilation reduced the incidence of BPD and respiratory morbidity at 18 to 22 months corrected age. Nasal intermittent positive pressure ventilation reduced treatment failure rates compared to CPAP, but not bronchopulmonary dysplasia (BPD). LISA compared with intubation and surfactant delivery reduced BPD, but there is no evidence from randomised trials regarding long-term respiratory and neurodevelopmental outcomes. Synchronisation of positive pressure inflations with the infant's respiratory efforts used with volume targeting should be applied for infants requiring intubation as this strategy reduces BPD. A large RCT with long term follow up data demonstrated that prophylactic high frequency oscillatory ventilation (HFOV) improved respiratory and functional outcomes at school age, but those effects were not maintained after puberty. CLAC systems appear promising, but their effect on long term clinical outcomes has not yet been explored in randomised trials. Further studies are required to determine the role of newer ventilation modes such as neurally adjusted ventilator assist (NAVA). All such respiratory support strategies should be tested in randomised controlled trials powered to assess long-term outcomes.

Kaltsogianni, Ourania↗

Long-Term Total Solar Irradiance (TSI) Variability Trends: 1984-2004

The incoming total solar irradiance (TSI), typically referred to as the solar constant, is being studied to identify long-term TSI changes, which may trigger global climate changes. The TSI is normalized to the mean earth-sun distance. Studies of spacecraft TSI data sets confirmed the existence of 0.1 %, long-term TSI variability component with a period of 10 years. The component varied directly with solar magnetic activity associated with recent 10-year sunspot cycles. The 0.1 % TSI variability component is clearly present in the spacecraft data sets from the 1984-2004, Earth Radiation Budget Experiment (ERBE) active cavity radiometer (ACR) solar monitor; 1978-1993, Nimbus-7 HF; 1980-1989, Solar Maximum Mission [SMM] ACRIM; 1991-2004, Upper Atmosphere Research Satellite (UARS) ACRIM; 1996-2003, Solar and Heliospheric Observatory (SOHO)/VIRGO, Space Science (ATLAS), 2000-2004, ACRIMSAT; and 2003-2004 SOlar Radiation and Climate Experiment (SORCE) active cavity radiometer (ACR) missions. From October 1984, through March 2004, the ERBS/ERBE solar monitor was used to produce the longest continuous data set of total solar irradiance (TSI) variability measurements. The solar monitor is located on Shuttle Atmospheric Laboratory for Applications and the NASA Earth Radiation Budget Satellite (ERBS). Maximum TSI values occurred during the 1989-1991, and 1998-2002, time frames; while minimum [quiet sun] TSI levels occurred during 1986 and 1996. Recent ERBS measurements indicate that the TSI is decreasing to forecasted, minimum levels by 2006. Using the discontinuous non-operational Nimbus-7, SMM ACRIM, and UARS ACRIM mission TSI data sets, Wilson and Mordvinor (2003) suggested the existence of an additional long-term TSI variability component, 0.05 %, with a period longer than a decade. Analyses of the ERBS/ERBE data set do not support the Wilson and Mordvinor analyses approach because it used the Nimbus-7 data set which exhibited a significant ACR response shift of 0.7 Wm-2

Lee, Robert Benjamin, III↗

A self-consistent model for the long-term gamma-ray spectral variability of Cygnus X-1

The long-term transitions of the black hole candidate Cygnus X-1 (between the states gamma-1, gamma-2, and gamma-3) include the occasional appearance of a strong nearly-MeV bump (gamma-1), whose strength appears to be anticorrelated with the continuum flux (below 400 keV) due to the Compton upscattering of cold disk photons by the inner, hot corona. We develop a self-consistent disk picture in which the bump is seen as due to the self-Comptonization of bremsstrahlung photons emitted predominantly near the plane of the corona itself. A decrease by a factor of about two in the viscosity parameter alpha is responsible for quenching this bump and driving the system to the gamma-2 state, whereas a transition from gamma-2 to gamma-3 appears to be induced by an increase of about 25 percent in the accretion rate M. In view of the fact that most of the transitions observed in this source seem to be of the gamma-2-gamma-3 variety, we conclude that much of the long-term gamma-ray spectral variability in Cygnus X-1 is due to these small fluctuations in M. The unusual appearance of the gamma-1 state apparently reflects a change in the dissipative processes within the disk.

Melia, Fulvio↗

Smart Structures for Vibration Control on Long-Term Space Exploration and Habitation Missions

The current vision for space exploration focuses on human missions to the Moon, Mars, and beyond. To support these goals, it is certain that new vehicles and intermediate bases will be developed, whether that means simply re-direction of the ISS as a "mission research facility" or construction of a lunar base. Since these facilities are expected to be constructed from inherently light-weight materials, this work examines some of the potential sources of vibration and noise as well as means for controlling these vibrations. Many of the operating components within these facilities, such as pumps, fans, and motors, will produce vibrations during operation. These vibrations become structure in which they are housed. Resonances can impact acoustic noise levels and noise quality within the environment, possibly affecting crew health and productivity. For long-term missions in particular, it is expected that crew members will spend significant portions of their time restrained in the structure, such as in seats. As a result, the general health and well-being of the crew can be improved by limiting the harmful effects of human exposure to long-term audible and tactile vibration input. Besides the human factor, this work also examines some operational considerations in which vibrations play an important role. Vibrations can impact the environment for science and in-situ manufacturing research within these vehicles. Since a benign vibratory environment is beneficial for most types of science experiments, there is a need for various forms of vibration control. Because the operational characteristics of a vehicle can change during a long-term mission, it is further expected that the characteristics of many of the vibratory excitations will change with time. Consequently, the form of vibration control needed to improve overall habitability and usefulness of the vehicle or element for exploration missions will rely to some degree on the vibration control system's ability to adapt. To address these needs, this work also examines the development and use of smart materials to tune the dynamic characteristics of the structure in a passive sense. One prime example is the use of an adaptive electrical shunt connected to a piezoelectric patch in order to provide tuned passive vibration damping. The work also examines the use of active vibration control, such as by applying power to that same piezoelectric patch. The overall goal is to examine the use of smart structures that can react to the environment thereby improving the overall living, working, and learning environment for these long-term missions.

Gattis, Christy B.↗

Long-term motion in a restricted problem of rotational motion

A method of general perturbations, based on the use of Lie series to generate approximate canonical transformations, is applied to study the long-term effects of gravity-gradient torque and orbital evolution on the rotational motion of a triaxial, rigid satellite. The center of mass of the satellite is constrained to move in an elliptic orbit about an attracting point mass. The orbit, which has a constant inclination, is constrained to precess and spin with constant rates. The method of general perturbations is used to obtain the Hamiltonian for the nonresonant secular and long-period rotational motion of the satellite to second order in n/omega sub 0, where n is the orbital mean motion of the center of mass and omega sub 0 is a reference value of the magnitude of the satellite's rotational angular velocity. The differential equations derivable from the transformed Hamiltonian are integrable, and the solution for the long-term motion may be expressed in terms of Jacobian elliptic functions and elliptic integrals. Geometrical aspects of the long-term rotational motion are discussed, and a comparison of theoretical results with observations is made.

Cochran, J. E.↗

ISS Regenerative Life Support: Challenges and Success in the Quest for Long-Term Habitability in Space

The International Space Station's (ISS) Regenerative Environmental Control and Life Support System (ECLSS) was launched in 2008 to continuously recycle urine and crew sweat into drinking water and oxygen using brand new technologies. This functionality was highly important to the ability of the ISS to transition to the long-term goal of 6-crew operations as well as being critical tests for long-term space habitability. Through the initial activation and long-term operations of these systems, important lessons were learned about the importance of system redundancy and operational workarounds that allow Systems Engineers to maintain functionality with limited on-orbit spares. This presentation will share some of these lessons learned including how to balance water through the different systems, store and use water for use in system failures and creating procedures to operate the systems in ways that they were not initially designed to do.

Bazley, Jesse↗

Advanced Long-Term Environmental Monitoring Systems (ALTEMIS) Artificial Intelligence Data Management Plan

Across the Department of Energy’s Environmental and Legacy Management sites, complex groundwater plumes exist that will require long-term monitoring to ensure remedial actions that have been put in place remain effective decades into the future. The current monitoring paradigm predominantly consists of groundwater well sampling, whereby samples are collected, concentrations analyzed, and plume anomalies are detected after they have occurred. The Advanced Long Term Environmental Monitoring Systems (ALTEMIS) program is a multi-lab, multi-institution team of researchers that is deploying spatially integrative technologies (i.e., real-time in situ sensor networks), coupled with artificial intelligence and machine learning, to establish a more proactive monitoring paradigm. Within this approach, plume anomalies can be predicted, and corrective actions can be established prior to the occurrence, offering a more cost-effective and robust approach to long-term monitoring. The team has deployed a variety of different in situ sensing technologies at the Savannah River Site’s F-Area Hazardous Waste Management Facility around the F-Area Seepage Basins, which are unlined basins that received 7 billion liters of acidic low-level radioactive waste from the 1950s until the late 1980s. The technologies and techniques that the team is deploying are intended to ensure that the remedial actions that have been taken by the site remain effective decades into the future. Foundational to this approach is a robust, integrated data management and analysis plan to ensure accurate and timely reporting from the variety of sensor systems that are in place. This report will outline the data management plan that has been implemented by the ALTEMIS team at the Savannah River Site and will serve as a blueprint as the technology is translated to new sites across the DOE Complex.

54 ENVIRONMENTAL SCIENCES↗

Characterizing the Aging of Alphasense NO2 Sensors in Long-term Field Deployments

Low-cost NO2 sensors have been widely deployed for atmospheric sampling. While their initial performance has been characterized, few studies have examined their long-term degradation. This study focused on the performance of Alphasense low-cost NO2 sensors (NO2-B42F and NO2-B43F) over 4 years (2016–2020). A total of 29 NO2 sensors from 10 batches were collocated 78 times at two sites with reference instruments. Raw signals from “functional” NO2 sensors correlated linearly with reference NO2 concentrations. After long-term deployment, sensor raw signals started to deviate from reference NO2 concentrations due to sensor aging, an accumulated effect after sensor unpacking. Several sensors eventually became “non-functional” as sensor raw signals showed no correlation with reference NO2 concentrations. Sensor aging and non-functionality may be primarily caused by expiration of the ozone (O3) scrubber built into these sensors so that sensors responded to both ambient NO2 and O3. The influence of O3 on sensor response is quantified through the permutation importance method. Most of the sensors are non-functional after approximately 200–400 days of deployment, and no sensor was functional after 400 days of deployment. This result agrees well with the estimated lifetime of the built-in ozone scrubbers considering the ambient ozone concentration in the Pittsburgh area where these sensors were deployed. To ensure reliable data quality in long-term field deployments, we recommend collocating NO2 sensors with reference instruments regularly after 200–400 days of deployment to identify and replace non-functional sensors in a timely manner.

NO2sensors↗

Understanding the interdiffusion behavior and determining the long term stability of tungsten fiber reinforced niobium-base matrix composite systems

The long term interdiffusional stability of tungsten fiber reinforced niobium alloy composites is addressed. The matrix alloy that is most promising for use as a high temperature structural material for reliable long-term space power generation is Nb1Zr. As an ancillary project to this program, efforts were made to assess the nature and kinetics of interphase reaction between selected beryllide intermetallics and nickel and iron aluminides.

Tien, John K.↗

Long‐term yields in annual and perennial bioenergy crops in the Midwestern United States

Abstract Many yield predictions in perennial bioenergy species have been made based on data collected during the establishment phase of growth or a limited number of long‐term studies. Few studies compare multiple perennial crops with the dominant agricultural vegetation of the landscape over long time periods. Here, we present the results of 11 years of perennial crop management on fertile agricultural soils in central Illinois, compared with conventional row crop maize/soybean ( Zea mays L., Glycine max L.) production. We examined the long‐term productivity and drought susceptibility of Miscanthus x giganteus Greef et. Deu. ex. Hodkinson et Renvoize (miscanthus), Panicum virgatum L., Cave‐in‐Rock cultivar (switchgrass), and a native prairie mix, in contrast to annual maize/soybean agriculture. Long‐term yields for miscanthus and switchgrass failed to reach initial predictions made during the establishment phase; however, in miscanthus, the 11 th year of production shows little progressive yield loss with age, exceeding the modeled limit for the onset of age‐related decline. Harvest timing and differences in yields from hand and machine harvests in perennial crops likely contribute to overestimates of potential yields. Application of fertilizer to mature miscanthus resulted in significant increases in yield after a severe drought, though modeled effects of management and drought in miscanthus point to a more complex mechanism for yield response.

09 BIOMASS FUELS↗

Space station experiment definition: Long term cryogenic fluid storage

A preliminary design of an experiment to demonstrate and evaluate long-term cryogenic fluid storage and transfer technologies has been performed. This Long-Term Cryogenic Fluid Storage (LTCFS) experiment is a Technology Development Mission (TDM) experiment proposed by the NASA Lewis Research Center to be deployed on the Initial Operational Capability (IOC) space station. Technologies required by future orbital cryogenic systems such as Orbital Transfer Vehicles (OTV's) were defined, and critical technologies requiring demonstration were chosen to be included in the experiment. A three-phase test program was defined to test the following types of technologies: (1) Passive Thermal Technologies; (2) Fluid Transfer Technologies; and (3) Active Refrigeration Technologies. The development status of advanced technologies required for the LTCFS experiment is summarized, including current, past and future programs.

Riemer, David H.↗

EGS Collab Experiment 1: Time-series geochemistry data of the long-term circulation test

This submission presents the weekly geochemistry data of the long-term flow test performed within EGS Collab Experiment 1 from early 2019 to early 2020. The fluids from each producing borehole/interval (PI, PB, PDT and PST) along with the injectate were sampled roughly weekly from April 2019 to January 2020 for geochemistry analysis. The geochemical measurement was part of a long-term microbial profiling project (see details in the PNAS paper linked below). Additional background and methodologies are available in the PNAS paper linked bellow.

15 GEOTHERMAL ENERGY↗

Generating a Long-Term Land Data Record from the AVHRR and MODIS Instruments

The goal of NASA's Land Long Term Iiata Record (LTDR) project is to produce a consistent long term data set from the AVHRR and MODIS instruments for land climate studies. The project will create daily surface reflectance and normalized difference vegetation index (NDVI) products at a resolution of 0.05 deg., which is identical to the Climate Modeling Grid (CMG) used for MODIS products from EOS Terra and Aqua. Higher order products such as burned area, land surface temperature, albedo, bidirectional reflectance distribution function (BRDF) correction, leaf area index (LAI), and fraction of photosyntheticalIy active radiation absorbed by vegetation (fPAR), will be created. The LTDR project will reprocess Global Area Coverage (GAC) data from AVHRR sensors onboard NOAA satellites by applying the preprocessing improvements identified in the AVHRR Pathfinder Il project and atmospheric and BRDF corrections used in MODIS processing. The preprocessing improvements include radiometric in-flight vicarious calibration for the visible and near infrared channels and inverse navigation to relate an Earth location to each sensor instantaneous field of view (IFOV). Atmospheric corrections for Rayleigh scattering, ozone, and water vapor are undertaken, with aerosol correction being implemented. The LTDR also produces a surface reflectance product for channel 3 (3.75 micrometers). Quality assessment (QA) is an integral part of the LTDR production system, which is monitoring temporal trands in the AVHRR products using time-series approaches developed for MODIS land product quality assessment. The land surface reflectance products have been evaluated at AERONET sites. The AVHRR data record from LTDR is also being compared to products from the PAL (Pathfinder AVHRR Land) and GIMMS (Global Inventory Modeling and Mapping Studies) systems to assess the relative merits of this reprocessing vis-a-vis these existing data products. The LTDR products and associated information can be found at http://ltdr.nascom.nasa.gov/ltdr/ltdr.html.

Pedelty, Jeffrey↗

Observation of a Long-Term Spin-up Trend in 4U 1538-52

The high-mass X-ray pulsar 4U 153 8-52 has been continually monitored by the Burst and Transient Source Experiment (BATSE) on Compton Gamma-Ray Observatory. These observations permit the construction of long-term pulse frequency and intensity histories. The frequency history reveals that a reversal of the long-term trend in the accretion torque, from spinning down to spinning up, has occurred, probably in 1988. This is the first time a long-term change is known to have occurred for this source, The magnitude of the average absolute value of (dot-nu / nu) is approximately 10(exp -11)/s over an interval of approximately 5 year is similar during spin-down and spin-up. Shorter term pulse frequency variations of either sign are also observed. The power density spectrum of fluctuations in angular acceleration is consistent with white noise on timescales from 16 to 1600 days. It can be well fit with a power law with a power-law index of 0.10 plus or minus 0.21 and white noise strength of (7.6 +/- 1.6) x 10(exp -21) (Hz/s(exp 2)/Hz). These observations are also used to set 95% confidence level lower and upper limits on the rate of orbital period change, -3.9< dot-P orb /P orb <2. 1, in units of 10(exp -6) yr(exp -1).

Rubin, B. C.↗