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At least 181 records · Page 10

Aerospace medicine and biology: A continuing bibliography with indexes (supplement 100)

Subject coverage concentrates on the biological, physiological, psychological, and environmental effects to which man is subjected during and following simulated or actual flight in the earth's atmosphere or in interplanetary space. Reference describing similar effects on biological organisms of lower order are also included. Such related topics as sanitary problems, pharmacology, toxicology, safety and survival, life support systems, exobiology, and personnel factors receive appropriate attention. Each entry consists of a standard citation accompanied by its abstract.

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A cumulative index to a continuing bibliography on aerospace medicine and biology, January 1972

Subject coverage concentrates on the biological, physiological, psychological, and environmental effects to which man is subjected during and following simulated or actual flight in the earth's atmosphere or in interplanetary space. References describing similar effects on biological organisms of lower order are also included. Such related topics as sanitary problems, pharmacology, toxicology, safety and survival, life support systems, exobiology, and personnel factors receive appropriate attention. Each entry consists of a standard citation accompanied by its abstract.

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Aerospace medicine and biology: A continuing bibliography with indexes, supplement 107, October 1972

This Supplement of Aerospace Medicine and Biology lists 353 reports, articles, and other documents announced during September 1972 in Scientific and Technical Aerospace Reports or in International Aerospace Abstracts. In its subject coverage, Aerospace Medicine and Biology concentrates on the biological, physiological, psychological, and environmental effects to which man is subjected during and following simulated or actual flight in the earth's atmosphere or in interplanetary space. References describing similar effects of biological organisms of lower order are also included. Such related topics as sanitary problems, pharmacology, toxicology, safety and survival, life support systems, exobiology, and personnel factors receive appropriate attention. In general, emphasis is placed on applied research, but references to fundamental studies and theoretical principles related to experimental development also qualify for inclusion.

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A flame-resistant modified polystyrene

Several modified polystyrenes have been developed that are self-extinguishing in air. Information is included in report that also describes molding and fabrication properties, toxicology, and thermal behavior of the polymers.

Karle, D. W.↗

Aerospace Medicine and Biology: A continuing bibliography with indexes, supplement 139

The biological, physiological, psychological, and environmental effects to which man is subjected during and following simulated or actual flight in the earth's atmosphere or in interplanetary space are referenced. Similar effects on biological organisms of lower order are also included. Related topics such as sanitary problems, pharmacology, toxicology, safety and survival, life support systems, exobiology, and personnel factors are discussed. Applied research is emphasized, but references to fundamental studies and theoretical principles related to experimental development are also included. A total of 242 reports, articles, and other documents are listed.

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Flame resistant nontoxic polymer development

A number of homopolymers, copolymers, and terpolymers were synthesized employing styrene and four derivatives of diphenyl-p-styrylphosphine. The various polymeric compositions were prepared by two processes, (1) monomer bulk polymerizations and (2) substitution of preformed polydiphenyl-p-styrylphosphine. Results indicate that the majority of the compositions exhibit superior melting and flame retardant characteristics as compared to polystyrene, but are inferior in molding and film forming capability. Terpolymerization appears to result in the materials with the best overall combination of properties. Toxicological evaluation of three representative basic compositions in the form of molded washers showed that no mortalities occurred among the test animals exposed to the products of the oxidative thermal decomposition of the three materials.

Paciorek, K. L.↗

Aerospace Medicine and Biology: A continuing bibliography with indexes, supplement 143

This supplement to Aerospace Medicine and Biology (NASA SP-7011) lists 251 reports, articles and other documents announced during June 1975 in Scientific and Technical Aerospace Reports (STAR) or in International Aerospace Abstracts (IAA). The first issue of the bibliography was published in July 1964; since that time, monthly supplements have been issued. In its subject coverage, Aerospace Medicine and Biology concentrates on the biological, physiological, and environmental effects to which man is subjected during and following simulated or actual flight in the earth's atmosphere or in interplanetary space. References describing similar effects of biological organisms of lower order are also included. Such related topics as sanitary problems, pharmacology, toxicology, safety and survival, life support systems, exobiology, and personnel factors receive appropriate attention. In general, emphasis is placed on applied research, but references to fundamental studies and theoretical principles related to experimental development also qualify for inclusion.

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Studies in neuroendocrine pharmacology

The expertise and facilities available within the Medical Sciences Program section on Pharmacology were used along with informational input from various NASA sources to study areas relevant to the manned space effort. Topics discussed include effects of drugs on deprivation-induced fluid consumption, brain biogenic amines, biochemical responses to stressful stimuli, biochemical and behavioral pharmacology of amphetamines, biochemical and pharmacological studies of analogues to biologically active indole compounds, chemical pharmacology: drug metabolism and disposition, toxicology, and chemical methodology. Appendices include a bibliography, and papers submitted for publication or already published.

Maickel, R. P.↗

Concepts in health evaluation of commercial and industrial chemicals

A method is described for determining no toxic effect exposure levels based on short-term testing of industrial and commercial chemicals. Procedures for monitoring all organs and body functions for the presence or absence of toxicological effects are demonstrated using various laboratory animals.

Mcnamara, B. P.↗

Concentration-response data on toxicity of pyrolysis gases from six synthetic polymers

Concentration-response data are presented on the toxic effects of the pyrolysis gases from six synthetic polymers on Swiss Webster male mice, using a toxicity screening test method. The polymers consisted of one sample each of polycarbonate and polystyrene, and two samples each of polyethylene and acrylonitrile-butadiene-styrene (ABS). All six samples were evaluated using the rising temperature program, and three samples were evaluated using the fixed temperature program. The pyrolysis gases from polycarbonate, polyethylene, and ABS appeared to exhibit the concentration-response relationships commonly encountered in toxicology. The polystyrene sample gave variable results; probably due to poor reproducibility of the essentially anaerobic pyrolysis. Carbon monoxide seemed to be the principal toxicant in the pyrolysis gases from polycarbonate and polyethylene, but did not appear to be the principal toxicant in the pyrolysis gases from ABS.

Hilado, C. J.↗

Concentration-response data on toxicity of pyrolysis gases from some natural and synthetic polymers

Concentration-response data are presented on the toxic effects of the pyrolysis gases from some natural and synthetic polymers, using the toxicity screening test method developed at the University of San Francisco. The pyrolysis gases from wool, red oak, Douglas fir, polycaprolactam, polyether sulfone, polyaryl sulfone, and polyphenylene sulfide appeared to exhibit the concentration-response relationships commonly encountered in toxicology. Carbon monoxide seemed to be an important toxicant in the pyrolysis gases from red oak, Douglas fir, and polycaprolactam, but did not appear to have been the principal toxicant in the pyrolysis gases from polyether sulfone and polyphenylene sulfide.

Hilado, C. J.↗

Conference on Fire Resistant Materials (FIREMEN): A compilation of presentations and papers

The proceedings of the NASA Fire Resistant Materials Engineering (FIREMEN) Program held at Ames Research Center on April, 13, 14, 1978 are reported. The purpose of the conference was to discuss the results of NASA in the field of aircraft fire safety and fire resistant materials. The program components include the following: (1) large-scale testing; (2) fire toxicology; (3) polymeric materials; and (4) bibliography related and/or generated from the program.

Kourtides, D. A.↗

Conference on Fire Resistant Materials: A compilation of presentations and papers

The proceedings of the NASA IRE Resistant Materials Engineering (FIREMEN) Program held at Boeing Commercial Airplane Company, Seattle, Washington, on March 1-2, 1979 are reported. The conference was to discuss the results of research by the National Aeronautics and Space Administration in the field of aircraft fire safety and fire-resistant materials. The program topics include the following: (1) large-scale testing; (2) fire toxicology; (3) polymeric materials; and (4) fire modeling.

Kourtides, D. A.↗

A comparative study of the toxicity of the combustion products of Tedlar and a fluorenone-polyester film

The relative toxicity in rats resulting from a 30 minute exposure to the combustion products of two materials, Tedlar and fluorenone-polyester film was assessed. The combustion products were generated into a static exposure system using a laboratory-scale furnace. The toxicity was assessed using the primary measurements employed in a more detailed overall toxicity evaluation. The toxicological events observed during the 30 minute exposure are reported.

Farrar, D. G.↗

Weight control and restraint of laboratory rats

The use of restrained and confined rats in some procedures used in combustion toxicology introduces the problems of obtaining rats of the appropriate size for the apparatus, and of identifying any artifacts resulting from the use of restraint alone. Feeding studies indicate that controlled feeding of fast-growing strains such as the Sprague-Dawley can hold rat size essentially constant for significant periods of time. The undesirable aspects are the need to cage the animals individually, with resultant psychological as well as metabolic effects. Restraint studies of slow-growing strains such as the Fischer 344 indicate that denying access to food and water for periods of several hours at a time interrupts normal gain only temporarily.

Hilado, C. J.↗

Pyrolysis of polymeric materials. I - Effect of chemical structure, temperature, heating rate, and air flow on char yield and toxicity

Various polymeric materials, including synthetic polymers and cellulosic materials, were evaluated at different temperatures, heating rates and air flow rates for thermophysical and toxicological responses. It is shown that char yields appeared to be a function of air access as much as of the chemical structure of the material. It is stated that the sensitivity of the apparent thermal stability of some materials to air access is so marked that thermogravimetric studies in oxygen-free atmospheres may be a consistently misleading approach to comparing synthetic polymers intended to increase fire safety. Toxicity also appeared to be a function of temperature and air access as much as of the chemical structure of the material. Toxicity of the gases evolved seemed to increase with increasing char yield for some polymers.

Hilado, C. J.↗

Contaminants

Spacecraft contaminants, their sources, and their toxicological effects are summarized. The problems of identifying toxic hazards, establishing standards for their concentrations, and designing removal systems are discussed.

Kaplan, H. L.↗

Aerospace Medicine and Biology: A continuing bibliography with indexes, supplement 212

A bibliography listing 146 reports, articles, and other documents introduced into the NASA scientific and technical information system is presented. The subject coverage concentrates on the biological, psychological, and environmental factors involved in atmospheric and interplanetary flight. Related topics such as sanitary problems, pharmacology, toxicology, safety and survival, life support systems, and exobiology are also given attention.

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