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At least 181 records · Page 10

Method and apparatus for assessing cardiovascular risk

The method for assessing risk of an adverse clinical event includes detecting a physiologic signal in the subject and determining from the physiologic signal a sequence of intervals corresponding to time intervals between heart beats. The long-time structure of fluctuations in the intervals over a time period of more than fifteen minutes is analyzed to assess risk of an adverse clinical event. In a preferred embodiment, the physiologic signal is an electrocardiogram and the time period is at least fifteen minutes. A preferred method for analyzing the long-time structure variability in the intervals includes computing the power spectrum and fitting the power spectrum to a power law dependence on frequency over a selected frequency range such as 10.sup.-4 to 10.sup.-2 Hz. Characteristics of the long-time structure fluctuations in the intervals is used to assess risk of an adverse clinical event.

Albrecht, Paul↗

Genetic Inventory Task Final Report

Contaminant terrestrial microbiota could profoundly impact the scientific integrity of extraterrestrial life-detection experiments. It is therefore important to know what organisms persist on spacecraft surfaces so that their presence can be eliminated or discriminated from authentic extraterrestrial biosignatures. Although there is a growing understanding of the biodiversity associated with spacecraft and cleanroom surfaces, it remains challenging to assess the risk of these microbes confounding life-detection or sample-return experiments. A key challenge is to provide a comprehensive inventory of microbes present on spacecraft surfaces. To assess the phylogenetic breadth of microorganisms on spacecraft and associated surfaces, the Genetic Inventory team used three technologies: conventional cloning techniques, PhyloChip DNA microarrays, and 454 tag-encoded pyrosequencing, together with a methodology to systematically collect, process, and archive nucleic acids. These three analysis methods yielded considerably different results: Traditional approaches provided the least comprehensive assessment of microbial diversity, while PhyloChip and pyrosequencing illuminated more diverse microbial populations. The overall results stress the importance of selecting sample collection and processing approaches based on the desired target and required level of detection. The DNA archive generated in this study can be made available to future researchers as genetic-inventory-oriented technologies further mature.

microbial diversity↗

A Method of Compliance for Achieving Target Collision Risk in UTM Operations

This work proposes a method of compliance to ensure that the collision risks among small unmanned aircraft systems meet the target level of safety. This method presents what is needed for a strategic conflict detection service to achieve the target level of safety when conflict between operational intents are not permitted in nominal situations. A volume-based collision risk model is first developed to calculate the UA-to-UA collision risk given any two operational intent volumes. With this collision risk model, a test strategy is then proposed to assess if a strategic conflict detection service can reduce the collision risk and meet the target level of safety. The method also specifies operational data that are required to be collected to verify if requirements on conformance are being met. Additionally, two new requirements are identified and proposed by this method beyond the current standard for strategic conflict detection. In the sensitivity analysis, three main factors contributing to the collision risk are investigated. The analysis shows that buffers should be considered in a strategic conflict detection service when deconflicting operational intents. The results also reveal that the selection of test cases plays an important role in evaluating the strategic conflict detection service, and they should be representative and sufficiently complex in evaluation tests.

Collision Risk↗

Detecting Airborne Mercury by Use of Palladium Chloride

Palladium chloride films have been found to be useful as alternatives to the gold films heretofore used to detect airborne elemental mercury at concentrations of the order of parts per billion (ppb). Somewhat more specifically, when suitably prepared palladium chloride films are exposed to parts-per-billion or larger concentrations of airborne mercury, their electrical resistances change by amounts large enough to be easily measurable. Because airborne mercury adversely affects health, it is desirable to be able to detect it with high sensitivity, especially in enclosed environments in which there is a risk of leakage of mercury from lamps or other equipment. The detection of mercury by use of gold films involves the formation of gold/mercury amalgam. Gold films offer adequate sensitivity for detection of airborne mercury and could easily be integrated into an electronic-nose system designed to operate in the temperature range of 23 to 28 C. Unfortunately, in order to regenerate a gold-film mercury sensor, one must heat it to a temperature of 200 C for several minutes in clean flowing air. In preparation for an experiment to demonstrate the present sensor concept, palladium chloride was deposited from an aqueous solution onto sets of gold electrodes and sintered in air to form a film. Then while using the gold electrodes to measure the electrical resistance of the films, the films were exposed, at a temperature of 25 C, to humidified air containing mercury at various concentrations from 0 to 35 ppb (see figure). The results of this and other experiments have been interpreted as signifying that sensors of this type can detect mercury in room-temperature air at concentrations of at least 2.5 ppb and can readily be regenerated at temperatures <40 C.

Ryan, Margaret↗

Evaluation of the Simple Safe Site Selection (S4) Hazard Detection Algorithm Using Helicopter Field Test Data

Small scale terrain hazards, such as rocks, slopes, and craters, can pose significant risk to landing spacecraft and rover or payload deployment. Onboard Hazard Detection and Avoidance (HDA) systems scan and analyze the landing area for these hazards in real time during descent, and divert the spacecraft to the safest touchdown site. The computationally efficient Simple Safe Site Selection (S4) algorithm combined with a flash LIDAR is an HDA system geared towards small robotic spacecraft. Rather than creating and analyzing a digital elevation map (DEM) from potentially many overlapping range images, S4 operates directly on a single flash LIDAR image. Extending prior work that has analyzed S4 performance for Mars landing using extensive simulations, this paper evaluates S4 performance using actual flash LIDAR images of an artificial hazard field acquired during a 2014 helicopter field test in Death Valley, CA. In particular, we describe LIDAR characterization and calibration, creation of ground truth elevation and safety maps, creation of ground truth sensor poses, actual S4 algorithm processing, and performance analysis. The results show that the safety cost images produced by S4 are remarkably close to the ground truth safety map (computed offline by an HDA algorithm developed under the Autonomous Landing and Hazard Avoidance (ALHAT) project) at significantly reduced computational cost, confirming S4 as a viable candidate algorithm for onboard spacecraft HDA.

Luna, Michael E.↗

A Method of Compliance for Achieving Target Collision Risk in UTM Operations

This work proposes a method of compliance to ensure that the collision risks among small unmanned aircraft systems meet the target level of safety. This method presents what is needed for a strategic conflict detection service to achieve the target level of safety when conflict between operational intents are not permitted in nominal situations. A volume-based collision risk model is first developed to calculate the UA-to-UA collision risk given any two operational intent volumes. With this collision risk model, a test strategy is then proposed to assess if a strategic conflict detection service can reduce the collision risk and meet the target level of safety. The method also specifies operational data that are required to be collected to verify if requirements on conformance are being met. Additionally, two new requirements are identified and proposed by this method beyond the current standard for strategic conflict detection. In the sensitivity analysis, three main factors contributing to the collision risk are investigated. The analysis shows that buffers should be considered in a strategic conflict detection service when deconflicting operational intents. The results also reveal that the selection of test cases plays an important role in evaluating the strategic conflict detection service, and they should be representative and sufficiently complex in evaluation tests.

UTM↗

A Method of Compliance for Achieving Target Collision Risk in UTM Operations

This work proposes a method of compliance to ensure that the collision risks among small unmanned aircraft systems meet the target level of safety. This method presents what is needed for a strategic conflict detection service to achieve the target level of safety when conflict between operational intents are not permitted in nominal situations. A volume-based collision risk model is first developed to calculate the UA-to-UA collision risk given any two operational intent volumes. With this collision risk model, a test strategy is then proposed to assess if a strategic conflict detection service can reduce the collision risk and meet the target level of safety. The method also specifies operational data that are required to be collected to verify if requirements on conformance are being met. Additionally, two new requirements are identified and proposed by this method beyond the current standard for strategic conflict detection. In the sensitivity analysis, three main factors contributing to the collision risk are investigated. The analysis shows that buffers should be considered in a strategic conflict detection service when deconflicting operational intents. The results also reveal that the selection of test cases plays an important role in evaluating the strategic conflict detection service, and they should be representative and sufficiently complex in evaluation tests.

UTM, Method of Compliance, collision risk↗

Streaming Analytics for Anomaly Detection in Large-Scale Data

Anomalous behavior poses serious risks to assured performance and reliability of complex, high-consequence systems. For spaceborne assets and their state-of-health (SOH) telemetry, the challenges of high-dimensional data of varying data types are compounded by computational limitations from size, weight, and power (SWaP) constraints as well as data availability. Automated anomaly detection methods tend to perform poorly under these constraints, while current operational approaches can introduce delays in response time due to the manual, retrospective processes for understanding system failures. As a result, presently deployed space systems, and those deployed in the near future, face situations where mission operations might be delayed or only be able to operate under degraded capabilities. Here, we examine a near-term lightweight solution that provides real-time detection capabilities for rare events and assess state-of-the-art anomaly detection techniques against real SOH telemetry from space platforms. This report describes our methodology and research, which could support more automated capabilities for comprehensive space operations as well as for other resource-constrained edge applications.

97 MATHEMATICS AND COMPUTING↗

Intelliquench: An Adaptive Machine Learning System for Detection of Superconducting Magnet Quenches

In superconducting magnets, the irreversible transition of a portion of the conductor to resistive state is called a “quench.” Having large stored energy, magnets can be damaged by quenches due to localized heating, high voltage, or large force transients. Unfortunately, current quench protection systems can only detect a quench after it happens, and mitigating risks in Low Temperature Superconducting (LTS) accelerator magnets often requires fast response (down to ms). Additionally, protection of High Temperature Superconducting (HTS) magnets is still suffering from prohibitively slow quench detection. In this study, we lay the groundwork for a quench prediction system using an auto-encoder fully-connected deep neural network. After dynamically trained with data features extracted from acoustic sensors around the magnet, the system detects anomalous events seconds before the quench in most of our data. While the exact nature of the events is under investigation, we show that the system can “forecast” a quench before it happens under magnet training conditions through a randomized experiment. This opens up the way of integrated data processing, potentially leading to faster and better diagnostics and detection of magnet quenches

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

A validation of satellite derived cyanobacteria detections with state reported events and recreation advisories across U.S. lakes

Cyanobacteria harmful algal blooms (cyanoHABs) negatively affect ecological, human, and animal health. Traditional methods of validating satellite algorithms with data from water samples are often inhibited by the expense of quantifying cyanobacteria indicators in the field and the lack of public data. However, state recreation advisories and other recorded events of cyanoHAB occurrence reported by local authorities can serve as an independent and publicly available dataset for validation. State recreation advisories were defined as a period delimited by a start and end date where a warning was issued due to detections of cyanoHABs over a state’s risk threshold. State reported events were defined as any event that was documented with a single date related to cyanoHABs. This study examined the presence-absence agreement between 160 state reported cyanoHAB advisories and 1,343 events and cyanobacteria biomass estimated by a satellite algorithm called the Cyanobacteria Index (CI(cyano)). The true positive rate of agreement with state recreation advisories was 69% and 60% with state reported events. CI(cyano) detected a reduction or absence in cyanobacteria after 76% of the recreation advisories ended. CI(cyano) was used to quantify the magnitude, spatial extent, and temporal frequency of cyanoHABs; each of these three metrics were greater (r > 0.2) during state recreation advisories compared to non-advisory times with effect sizes ranging from small to large. This is the first study to quantitatively evaluate satellite algorithm performance for detecting cyanoHABs with state reported events and advisories and supports informed management decisions with satellite technologies that complement traditional field observations.

remote sensing↗

Advanced Laboratory and Field Arrays: Debris Modeling, Detection,& Mitigation (Task 1)

The statement of project objectives for this task was: develop tools, methods and models to assess, and mitigate the risk of damage to MHK infrastructure from woody debris. Develop the capability to detect woody debris using sonar and/or physical methods for purposes of characterizing debris statistics in river (at UAF’s Tanana River Test Site) and near-shore wave (at Yakutat, AK) environments and to activate debris mitigation measures. Develop debris impact risk maps and tables using statistics on debris size, geometry, type, prevalence, mobility and location. Improve and apply the COUPi discrete element method (DEM) to develop models of debris movement and impact on MHK infrastructure to evaluate risk of damage, and interference, to operations from debris. The proposed final deliverable for the task was a set of tools or techniques for providing estimates of the probability of debris impact, and resulting impact forces, on MHK infrastructure as a function of debris size, type, wave regime, and current velocity. Such estimates are required to assess damage risks to operational MHK infrastructure.

13 HYDRO ENERGY↗

Evaluating the Effectiveness of a Detection and Deterrent System in Reducing Golden Eagle Fatalities at Operational Wind Facilities

The Renewable Energy Wildlife Institute (REWI) was appointed as the prime awardee of DOE award number DE-EE0007883 to lead a team of scientists, wind developers, and technology manufacturers toward the overarching goal of evaluating the effectiveness of the current DTBird system in minimizing the risk of golden eagles (Aquila chrysaetos) and other large soaring raptors from approaching the rotor-swept zone (RSZ) of operating wind turbines. As part of this goal, the team set out to 1) quantify the expected reduction in collision risk for golden eagles from operation of the detection and deterrence modules in a manner that supports the approach used by the U.S. Fish and Wildlife Service (USFWS) to assess and credit facility operators for their efforts to minimize predicted collision fatalities and 2) provide information to help improve the technology to maximize its effectiveness. DTBird is an automated detection and audio deterrent system created by the Spanish company Liquen, designed to discourage birds from entering the RSZ of spinning wind turbines. The system uses cameras to automatically detect airborne targets of interest, records each such event in an online database, and triggers a warning signal (loud sound) if the tracked object has moved close to the turbine. If the object moves even closer to the RSZ, a more aggressive dissuasion signal is broadcast. To meet our objectives, the team conducted a two-year experiment at the Goodnoe Hills wind facility in Washington state, in which 14 turbines were outfitted with DTBird units. Daily, each DTBird-equipped turbine was randomly assigned to a control or treatment group. Treatment turbines operated with DTBird running as intended—broadcasting warning or deterrent signals when DTBird detected a target within range. On control turbines, no sound signals were broadcast if a moving target triggered the DTBird system. The team also flew unmanned aerial vehicles (UAVs) designed to coarsely mimic the general size, weight, and coloration of golden eagles in programmed flight transects across DTBird detection ranges to quantify DTBird’s ability to detect intended targets and to evaluate factors that influence the probability of detection and DTBird’s response distances. Additionally, the team evaluated the behavioral responses of in situ eagles exposed to spinning turbines alone (visual and sound influences) versus spinning turbines plus broadcasted DTBird audio deterrents, to estimate the effectiveness of deterrence by the DTBird system. The data and results from these investigations were combined with those from a pilot study conducted at the Manzana Wind Power Project in California to better evaluate DTBird’s effectiveness across different landscapes.

17 WIND ENERGY↗

Software for Probabilistic Risk Reduction

A computer program implements a methodology, denoted probabilistic risk reduction, that is intended to aid in planning the development of complex software and/or hardware systems. This methodology integrates two complementary prior methodologies: (1) that of probabilistic risk assessment and (2) a risk-based planning methodology, implemented in a prior computer program known as Defect Detection and Prevention (DDP), in which multiple requirements and the beneficial effects of risk-mitigation actions are taken into account. The present methodology and the software are able to accommodate both process knowledge (notably of the efficacy of development practices) and product knowledge (notably of the logical structure of a system, the development of which one seeks to plan). Estimates of the costs and benefits of a planned development can be derived. Functional and non-functional aspects of software can be taken into account, and trades made among them. It becomes possible to optimize the planning process in the sense that it becomes possible to select the best suite of process steps and design choices to maximize the expectation of success while remaining within budget.

Hensley, Scott↗

Real-time Event Detection Using Rank Signatures of Real-world PMU Data

Timely detection of power system events is a crucial task, which can facilitate the implementation of remedial actions to improve reliability, resiliency, and security of the system. Meanwhile, the widespread deployment of phasor measurement units (PMUs) makes it possible to develop data-driven event detection techniques. However, relying purely on data without incorporating domain knowledge for the event detection task in power systems poses substantial security and stability risks due to issues associated with data misinterpretation and model accuracy. In this regard, we propose a real-time event detection method using real-world PMU data by incorporating domain knowledge to adequately capture the event signatures. Specifically, we track the change in rank signatures of PMU data to accurately localize the events. To optimize the detection process, we incorporate an offline Bayesian optimization algorithm to tune the parameters by efficiently searching for the best values. The experiments using the real-world PMU dataset from a U.S. interconnection show that the proposed event detection approach can efficiently detect the events from PMU data streams with high accuracy.

Ghasemkhani, Amir↗

Effects of social structure and management on risk of disease establishment in wild pigs

Contact heterogeneity among hosts determines invasion and spreading dynamics of infectious disease, thus its characterization is essential for identifying effective disease control strategies. Yet, little is known about the factors shaping contact networks in many 28 wildlife species and how wildlife management actions might affect contact networks. Wild pigs in North America are an invasive, socially-structured species that pose a health concern for domestic swine given their ability to transmit numerous devastating diseases 2 such as African swine fever (ASF). Using proximity loggers and GPS data from 48 wild pigs in Florida and South Carolina, USA, we employed a probabilistic framework to estimate weighted contact networks. We determined the effects of sex, social group, and spatial distribution (monthly home range overlap and distance) on wild pig contact. We also estimated the impacts of management-induced perturbations on contact and inferred their effects on ASF establishment in wild pigs with simulation. Social group membership was the primary factor influencing contacts. Between-group contacts depended primarily on space use characteristics, with fewer contacts among groups separated by >2 km and no contacts among groups >4 km apart within a month. Modeling ASF dynamics on the contact network demonstrated that indirect contacts resulting from baiting (a typical method of attracting wild pigs or game species to a site to enhance recreational hunting) increased the risk of disease establishment by ~33% relative to direct contact. Low-intensity population reduction (<5.9% of the population) had no detectable impact on contact structure but reduced predicted ASF establishment risk relative to no population reduction. Here, we demonstrate an approach for understanding the relative role of spatial, social, and individual-level characteristics in shaping contact networks and predicting their effects on disease establishment risk, thus providing insight for optimizing disease control in spatially- and socially-structured wildlife species.

59 BASIC BIOLOGICAL SCIENCES↗

Analyzing the Subjectivity of Hole-Type Image Quality Indicators for Radiography

Hole-type penetrameters used as image quality indicators (IQIs) for radiography have an inherent degree of subjectivity to their interpretation. The 1T (one times the thickness of the penetrameter) hole is so small, it can be difficult to distinguish from noise. It is suspected that an operator’s knowledge of the true location of the 1T hole may subconsciously influence a false positive identification of the 1T hole when in fact it cannot be discerned. In the case of computed radiography (CR), the size of the phosphor particles may lead to a noise pattern with features on the scale of the 1T hole. Per NASA-STD-5009, the 1T hole must be detected in order to achieve adequate sensitivity. This is based on the historical understanding that this sensitivity will enable detection of the minimum detectable flaw sizes listed in the standard. It’s important to understand if 1T sensitivity is being achieved, and the associated risk if not. This study sought to determine the true detectability of 1T-sized holes in aluminum and Inconel by creating and inspecting a set of penetrameters with randomly placed holes. Enough holes and vacant zones were created to enable a full probability of detection study with 90% detectability, 95% confidence. Testing is ongoing, but preliminary results have shown poor detectability. The detection rate is slightly better for Inconel than aluminum, slightly better using a micro-focus vs. mini-focus tube, and definitively better for film than CR. One of the key questions of this study is whether historical requirements for film are applicable for CR, and these initial findings suggest they may not be. There is also a requirement in the NASA standard for the minimum contrast-to-noise ratio of the hole. The results have shown that this numerical threshold does not correlate well with visual detection. This raises questions about the true nature of detection, in an age of image processing vs. human judgement. As the results indicate that the detection of 1T holes is unreliable, the next challenge will be determining what sensitivity is really achieved, and what is needed.

Erin Lanigan↗

Analyzing the Subjectivity of Hole-Type Image Quality Indicators for Radiography

Hole-type penetrameters used as image quality indicators (IQIs) for radiography have an inherent degree of subjectivity to their interpretation. The 1T (one times the thickness of the penetrameter) hole is so small, it can be difficult to distinguish from noise. It is suspected that an operator’s knowledge of the true location of the 1T hole may subconsciously influence a false positive identification of the 1T hole when in fact it cannot be discerned. In the case of computed radiography (CR), the size of the phosphor particles may lead to a noise pattern with features on the scale of the 1T hole. Per NASA-STD-5009, the 1T hole must be detected in order to achieve adequate sensitivity. This is based on the historical understanding that this sensitivity will enable detection of the minimum detectable flaw sizes listed in the standard. It’s important to understand if 1T sensitivity is being achieved, and the associated risk if not. This study sought to determine the true detectability of 1T-sized holes in aluminum and Inconel by creating and inspecting a set of penetrameters with randomly placed holes. Enough holes and vacant zones were created to enable a full probability of detection study with 90% detectability, 95% confidence. Testing is ongoing, but preliminary results have shown poor detectability. The detection rate is slightly better for Inconel than aluminum, slightly better using a micro-focus vs. mini-focus tube, and definitively better for film than CR. One of the key questions of this study is whether historical requirements for film are applicable for CR, and these initial findings suggest they may not be. There is also a requirement in the NASA standard for the minimum contrast-to-noise ratio of the hole. The results have shown that this numerical threshold does not correlate well with visual detection. This raises questions about the true nature of detection, in an age of image processing vs. human judgement. As the results indicate that the detection of 1T holes is unreliable, the next challenge will be determining what sensitivity is really achieved, and what is needed.

Erin Lanigan↗

Technology Development for Fire Safety in Exploration Spacecraft and Habitats

Fire during an exploration mission far from Earth is a particularly critical risk for exploration vehicles and habitats. The Fire Prevention, Detection, and Suppression (FPDS) project is part of the Exploration Technology Development Program (ETDP) and has the goal to enhance crew health and safety on exploration missions by reducing the likelihood of a fire, or, if one does occur, minimizing the risk to the mission, crew, or system. Within the past year, the FPDS project has been formalized within the ETDP structure and has seen significant progress on its tasks in fire prevention, detection, and suppression. As requirements for Constellation vehicles and, specifically, the CEV have developed, the need for the FPDS technologies has become more apparent and we continue to make strides to infuse them into the Constellation architecture. This paper describes the current structure of the project within the ETDP and summarizes the significant programmatic activities. Major technical accomplishments are identified as are activities planned for FY07.

Ruff, Gary A.↗