DOE OSTI · code-52646
DNA Sequencing Optimizer v0.1
Abstract
This is a software utility used to maximize next-generation sequencing data output without compromising quality values. The DNA Sequencing Optimizer is used to determine the optimal amount of library to load. To do this a supervised machine learning model predicts cluster density, a measure of how much DNA is bound to the sequence, from the concentration of DNA loaded. The output is a plot that is used by experimentalists to determine the best DNA library concentration to load onto the sequencer.
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Costello, Zachary, Chiniquy, Jennifer. 2020-07-27. DNA Sequencing Optimizer v0.1. https://doi.org/10.11578/dc.20210311.5
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