DOE OSTI · 1892675
Compositions and methods for inhibiting kinase activity
Abstract
The present invention features therapeutic compositions comprising an agent that specifically binds to a PIF pocket of Aurora A kinase and an agent that specifically binds to an ATP-binding site of Aurora A kinase, and the use of the therapeutic compositions to modulate Aurora A kinase for the treatment of cancer.
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Kern, Douglas, Zorba, Adelajda. 2022-03-08. Compositions and methods for inhibiting kinase activity. https://www.osti.gov/biblio/1892675
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