NASA NTRS ยท 20080006973
Optimized catalytic DNA-cleaving ribozymes
Abstract
The present invention discloses nucleic acid enzymes capable of cleaving nucleic acid molecules, including single-stranded DNA, in a site-specific manner under physiologic conditions, as well as compositions including same. The present invention also discloses methods of making and using the disclosed enzymes and compositions.
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Joyce, Gerald F.. 1996-12-03. Optimized catalytic DNA-cleaving ribozymes. https://ntrs.nasa.gov/citations/20080006973
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