Biosensors for DNA sequence detection

Vercoutere, Wenonah; Akeson, Mark

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NASA NTRS · 20040087948

Biosensors for DNA sequence detection

Vercoutere, Wenonah·Akeson, Mark

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Abstract

DNA biosensors are being developed as alternatives to conventional DNA microarrays. These devices couple signal transduction directly to sequence recognition. Some of the most sensitive and functional technologies use fibre optics or electrochemical sensors in combination with DNA hybridization. In a shift from sequence recognition by hybridization, two emerging single-molecule techniques read sequence composition using zero-mode waveguides or electrical impedance in nanoscale pores.

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Review Review Literature Biosensing Techniques DNA/analysis/chemistry Sequence Analysis, DNA/methods Nucleic Acid Hybridization Spectrometry, Fluorescence/methods Fiber Optics Models, Molecular Oligonucleotide Array Sequence Analysis Microchemistry/methods Electrochemistry/methods

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Vercoutere, Wenonah, Akeson, Mark. 2002-12-01. Biosensors for DNA sequence detection. https://ntrs.nasa.gov/citations/20040087948

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