Bioisolation on the Space Station

Abstract

Animal research on the Space Station presents the need for bioisolation, which is here defined as instrumental and operational provisions, which will prevent the exchange of particles greater than 0.3-micron size and microorganisms between crew and animals. Current design principles for the Biological Research Project thus call for: (1) use of specific pathogen-free animals; (2) keeping animals at all times in enclosed habitats, provided with microbial filters and a waste collection system; (3) placing habitats in a holding rack, centrifuge, and workbench, all equipped with particulate and odor filters, (4) washing dirty cage units in an equipment cleaner, with treatment and recycling of the water; (5) designing components and facilities so as to ensure maximal accessibility for cleaning; and (6) defining suitable operational procedures. Limited ground tests of prototype components indicate that proper bioisolation can thus be achieved.