Engineering PapersSearch

NASA NTRS · 19850019197

Percutaneous connectors

Abstract

A surface possessing a regular array of micro-pillars was evaluated with regard to its ability to control epithelial downgrowth at the percutaneous interface. A range of pillar sizes were applied to the vertical segment of T shaped Biomer (R) implants. These percutaneous tabs were implanted into the dorsum of cats for a period of 6 weeks using a standardized surgical technique. Comments were made post-operatively and at the time of retrieval. A quantitative scoring system was applied to these observations as well as histological results. As observed, the pillar morphology used displayed the ability to control epithelial downgrowth. Collagen ingrowth into the interpillar spaces and possibly direct interactions of the epithelial cells with the morphology may account for the inhibition. The reproducibility of epithelial inhibition is, however, limited by other factors which are currently not well understood. These factors and potential methods of assessment are discussed.

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Picha, G. J., Taylor, S. R.. 1981-09-01. Percutaneous connectors. https://ntrs.nasa.gov/citations/19850019197

Cite the original work for its findings. Save a collection to share your selection of sources.