TY - RPRT TI - De Novo Design of High‐Affinity Miniprotein Binders Targeting Francisella Tularensis Virulence Factor AU - Gokce‐Alpkilic, Gizem [Molecular Engineering and Sciences Institute University of Washington Seattle WA USA; Department of Medicinal Chemistry University of Washington Seattle WA USA; Institute for Protein Design University of Washington Seattle WA USA] (ORCID:0000000150094429) AU - Huang, Buwei [Institute for Protein Design University of Washington Seattle WA USA; Department of Biochemistry University of Washington Seattle WA USA; Department of Bioengineering University of Washington Seattle WA USA] AU - Liu, Andi [Department of Microbiology University of Washington Seattle WA USA] AU - Kreuk, Lieselotte S.M. [Department of Microbiology University of Washington Seattle WA USA] AU - Wang, Yaxi [Department of Microbiology University of Washington Seattle WA USA] AU - Adebomi, Victor [Department of Medicinal Chemistry University of Washington Seattle WA USA; Institute for Protein Design University of Washington Seattle WA USA] AU - Bueso, Yensi Flores [Institute for Protein Design University of Washington Seattle WA USA; Cancer Research @UCC University College Cork Cork Ireland] AU - Bera, Asim K. [Institute for Protein Design University of Washington Seattle WA USA] AU - Kang, Alex [Institute for Protein Design University of Washington Seattle WA USA] AU - Gerben, Stacey R. [Institute for Protein Design University of Washington Seattle WA USA] AU - Rettie, Stephen [Department of Medicinal Chemistry University of Washington Seattle WA USA; Institute for Protein Design University of Washington Seattle WA USA; Molecular and Cellular Biology Program University of Washington Seattle WA USA] AU - Vafeados, Dionne K. [Institute for Protein Design University of Washington Seattle WA USA] AU - Roullier, Nicole [Institute for Protein Design University of Washington Seattle WA USA] AU - Goreshnik, Inna [Institute for Protein Design University of Washington Seattle WA USA] AU - Li, Xinting [Institute for Protein Design University of Washington Seattle WA USA] AU - Baker, David [Institute for Protein Design University of Washington Seattle WA USA; Department of Biochemistry University of Washington Seattle WA USA; Howard Hughes Medical Institute University of Washington Seattle WA USA] AU - Woodward, Joshua J. [Department of Microbiology University of Washington Seattle WA USA] AU - Mougous, Joseph D. [Department of Microbiology University of Washington Seattle WA USA; Howard Hughes Medical Institute University of Washington Seattle WA USA; Microbial Interactions and Microbiome Center University of Washington Seattle WA USA] AU - Bhardwaj, Gaurav [Molecular Engineering and Sciences Institute University of Washington Seattle WA USA; Department of Medicinal Chemistry University of Washington Seattle WA USA; Institute for Protein Design University of Washington Seattle WA USA] PY - 2025 DO - 10.1002/anie.202516058 UR - https://www.osti.gov/biblio/3598460 ID - 3598460 ER -