Engineering topics

Zhang, David

Publications and source records attributed to Zhang, David.

4 records

DOE OSTI2023

Formate as an Energy Source to Allow Sugar Fermentation with No Net CO2 Generation: Integration of Electrochemistry with Fermentation

This poster summarizes at a high-level the scope of various groups' work on Formate as an Energy Source to Allow Sugar Fermentation with No Net CO2 Generation: Integration of Electrochemistry with Fermentation. The goals of this research are to develop and demonstrate an integrated process that electrochemically generates formate from CO2 and use the formate as an energy source for the fermentation of sugars to fatty acid methyl esters (FAME) without net CO2 generation wherein formate provides reducing equivalents for sugar fermentation and a chemical looping reactor system takes advantage of intermittent low-cost electricity from wind and solar resources.

BIOMASS FUELS,INORGANIC, ORGANIC, PHYSICAL, AND AN↗

DOE OSTI2022

Microcam: A Low Power and Privacy Preserving Multi-modal Platform for Occupancy Detection (Final Report)

Heating, ventilation, and air conditioning (HVAC) consumes a significant portion of the energy used in buildings. Much of this is wasted energy, used when buildings are either not occupied at all, or occupied well under their maximum design conditions. This project has focused on residential occupancy detection to autonomously control HVAC systems and save energy. Limitations of existing occupancy sensors include one or more of the following: (i) they employ sensors or algorithms that are not able to detect stationary occupants; (ii) they cannot classify the source of the motion (such as a pet); (iii) depending on the camera resolution and employed algorithms, they do not allow for embedded or onboard computation, and require external or cloud-based processing; (iv) many algorithms developed for camera-based systems are sensitive to lighting changes, and thus prone to missed detections or false alarms; (v) Most existing systems depend on adjustment of settings for different scenarios, complicating self-commissioning; (vi) they cannot provide high enough accuracy; (vii) they are costly; (viii) they are not battery-powered, thus limiting ease of use and installation. In this project, Syracuse University and its partner SRI have developed a low-cost, high accuracy, standalone residential occupancy sensing platform, referred to as the MicroCam, to address all of the aforementioned challenges. MicroCam can operate on typical alkaline batteries without relying on the “cloud” or external computing resources, and consists of low-power, Artificial Intelligence (AI)-based, IoT platforms. Each platform has multi-modal sensors and can process motion, audio and video data, and send binary occupancy result to a lead platform. All sensor data is processed locally on platforms, and the only transmitted data is the binary occupancy state. In addition, preliminary work has been done on images wherein occupants are not discernable. Thus, MicroCam is a standalone solution preserving privacy of the occupants.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

DOE OSTI2022

In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas

A newly validated target for tuberculosis treatment is phosphopantetheinyl transferase, an essential enzyme that plays a critical role in the biosynthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. The structure–activity relationships of a recently disclosed inhibitor, amidinourea (AU) 8918 (1), were explored, focusing on the biochemical potency, determination of whole-cell on-target activity for active compounds, and profiling of selective active congeners. These studies show that the AU moiety in AU 8918 is largely optimized and that potency enhancements are obtained in analogues containing a para-substituted aromatic ring. Preliminary data reveal that while some analogues, including 1, have demonstrated cardiotoxicity (e.g., changes in cardiomyocyte beat rate, amplitude, and peak width) and inhibit Ca v 1.2 and Na v 1.5 ion channels (although not hERG channels), inhibition of the ion channels is largely diminished for some of the para-substituted analogues, such as 5k (p-benzamide) and 5n (p-phenylsulfonamide).

60 APPLIED LIFE SCIENCES↗

DOE OSTI2011

Multimodal agile robots

Examples and implementations of various robotic mechanisms, devices, components, systems and techniques are provided, including multimodal robotic devices and systems. For example, a multimodal robot can be configured to autonomously reconfigure between two or more primary modes of operation. Such robots may be used in a wide range of applications, including reconnaissance, exploration, search and rescue, military, sports, personal assistance, education, and entertainment and toys. Described examples of multimodal robots can be wheeled robots that use two or more drive wheels to perform various motions and operations.

Bewley, Thomas R.↗