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Wilson, John W.

Publications and source records attributed to Wilson, John W..

At least 145 records · Page 8

Target correlation effects on neutron-nucleus total, absorption, and abrasion cross sections

Second order optical model solutions to the elastic scattering amplitude were used to evaluate total, absorption, and abrasion cross sections for neutron nucleus scattering. Improved agreement with experimental data for total and absorption cross sections is found when compared with first order (coherent approximation) solutions, especially below several hundred MeV. At higher energies, the first and second order solutions are similar. There are also large differences in abrasion cross section calculations; these differences indicate a crucial role for cluster knockout in the abrasion step.

Cucinotta, Francis A.↗

Transport methods and interactions for space radiations

A review of the program in space radiation protection at the Langley Research Center is given. The relevant Boltzmann equations are given with a discussion of approximation procedures for space applications. The interaction coefficients are related to solution of the many-body Schroedinger equation with nuclear and electromagnetic forces. Various solution techniques are discussed to obtain relevant interaction cross sections with extensive comparison with experiments. Solution techniques for the Boltzmann equations are discussed in detail. Transport computer code validation is discussed through analytical benchmarking, comparison with other codes, comparison with laboratory experiments and measurements in space. Applications to lunar and Mars missions are discussed.

Wilson, John W.↗

HZETRN: A heavy ion/nucleon transport code for space radiations

The galactic heavy ion transport code (GCRTRN) and the nucleon transport code (BRYNTRN) are integrated into a code package (HZETRN). The code package is computer efficient and capable of operating in an engineering design environment for manned deep space mission studies. The nuclear data set used by the code is discussed including current limitations. Although the heavy ion nuclear cross sections are assumed constant, the nucleon-nuclear cross sections of BRYNTRN with full energy dependence are used. The relation of the final code to the Boltzmann equation is discussed in the context of simplifying assumptions. Error generation and propagation is discussed, and comparison is made with simplified analytic solutions to test numerical accuracy of the final results. A brief discussion of biological issues and their impact on fundamental developments in shielding technology is given.

Wilson, John W.↗

Cellular repair/misrepair track model

A repair/misrepair cell kinetics model is superimposed onto the track structure model of Katz to provide for a repair mechanism. The model is tested on the repair-dependent data of Yang et al. and provides an adequate description of that data. The misrepair rate determines the maximum relative biological effectiveness (RBE), but similar results could arise from indirect X-ray lethality not include in the present model.

Wilson, John W.↗

Benchmark solutions for the galactic heavy-ion transport equations with energy and spatial coupling

Nontrivial benchmark solutions are developed for the galactic heavy ion transport equations in the straightahead approximation with energy and spatial coupling. Analytical representations of the ion fluxes are obtained for a variety of sources with the assumption that the nuclear interaction parameters are energy independent. The method utilizes an analytical LaPlace transform inversion to yield a closed form representation that is computationally efficient. The flux profiles are then used to predict ion dose profiles, which are important for shield design studies.

Ganapol, Barry D.↗

Nuclear reaction effects in use of newly recommended quality factor

The biological risk for energetic ion exposure cannot be reliably estimated exclusive of the target nuclear reaction products produced within the local tissue. A theoretical basis is derived for evaluating target fragment contributions that are evaluated for the newly proposed quality factor.

Shinn, Judy L.↗

Analyses of risks associated with radiation exposure from past major solar particle events

Radiation exposures and cancer induction/mortality risks were investigated for several major solar particle events (SPE's). The SPE's included are: February 1956, November 1960, August 1972, October 1989, and the September, August, and October 1989 events combined. The three 1989 events were treated as one since all three could affect a single lunar or Mars mission. A baryon transport code was used to propagate particles through aluminum and tissue shield materials. A free space environment was utilized for all calculations. Results show the 30-day blood forming organs (BFO) limit of 25 rem was surpassed by all five events using 10 g/sq cm of shielding. The BFO limit is based on a depth dose of 5 cm of tissue, while a more detailed shield distribution of the BFO's was utilized. A comparison between the 5 cm depth dose and the dose found using the BFO shield distribution shows that the 5 cm depth value slightly higher than the BFO dose. The annual limit of 50 rem was exceeded by the August 1972, October 1989, and the three combined 1989 events with 5 g/sq cm of shielding. Cancer mortality risks ranged from 1.5 to 17 percent at 1 g/sq cm and 0.5 to 1.1 percent behind 10 g/sq cm of shielding for five events. These ranges correspond to those for a 45 year old male. It is shown that secondary particles comprise about 1/3 of the total risk at 10 g/sq cm of shielding. Utilizing a computerized Space Shuttle shielding model to represent a typical spacecraft configuration in free space at the August 1972 SPE, average crew doses exceeded the BFO dose limit.

Weyland, Mark D.↗

LET analyses of biological damage during solar particle events

The effects of nuclear reactions on integral low-linear-energy-transfer (LET) protons spectra are studied, behind typical levels of spacecraft and body shielding, for the historically largest flares using the high-energy transport code BRYNTRN in conjunction with several biological damage models. The cellular track model of Katz provides an accurate description of cellular damage from heavy ion exposure. The track model is applied with BRYNTRN to provide a LET decomposition of survival and transformation rates for solar proton events. In addition, a fluence-based risk coefficient formalism is used to estimate Harderian gland-tumor induction in rodents and cataractogenesis in rabbits from solar flares, and a LET analysis is used to assess the relative contribution from target fragments on these biological endpoints.

Cucinotta, Francis A.↗

Radiation risk predictions for Space Station Freedom orbits

Risk assessment calculations are presented for the preliminary proposed solar minimum and solar maximum orbits for Space Station Freedom (SSF). Integral linear energy transfer (LET) fluence spectra are calculated for the trapped proton and GCR environments. Organ dose calculations are discussed using the computerized anatomical man model. The cellular track model of Katz is applied to calculate cell survival, transformation, and mutation rates for various aluminum shields. Comparisons between relative biological effectiveness (RBE) and quality factor (QF) values for SSF orbits are made.

Cucinotta, Francis A.↗

Analytical relationships of nuclear field and microdosimetric quantities for target fragmentation in tissue systems

A simple analytic formula for the nuclear fields formed by target fragmentation in tissue systems is derived using the continuous slowing down approximation (CSDA). The energy fluctuations in sensitive localized sites within the tissue system caused by these nuclear events are defined by microdosimetry. In that CSDA is used, the energy fluctuations exclude the role of secondary electrons. The relations also relate to the response of microdosimetric devices to nuclear fragmentation fields.

Wilson, John W.↗

Cellular track model of biological damage to mammalian cell cultures from galactic cosmic rays

The assessment of biological damage from the galactic cosmic rays (GCR) is a current interest for exploratory class space missions where the highly ionizing, high-energy, high-charge ions (HZE) particles are the major concern. The relative biological effectiveness (RBE) values determined by ground-based experiments with HZE particles are well described by a parametric track theory of cell inactivation. Using the track model and a deterministic GCR transport code, the biological damage to mammalian cell cultures is considered for 1 year in free space at solar minimum for typical spacecraft shielding. Included are the effects of projectile and target fragmentation. The RBE values for the GCR spectrum which are fluence-dependent in the track model are found to be more severe than the quality factors identified by the International Commission on Radiological Protection publication 26 and seem to obey a simple scaling law with the duration period in free space.

Cucinotta, Francis A.↗

Preliminary calculation of solar cosmic ray dose to the female breast in space mission

No regulatory dose limits are specifically assigned for the radiation exposure of female breasts during manned space flight. However, the relatively high radiosensitivity of the glandular tissue of the breasts and its potential exposure to solar flare protons on short- and long-term missions mandate a priori estimation of the associated risks. A model for estimating exposure within the breast is developed for use in future NASA missions. The female breast and torso geometry is represented by a simple interim model. A recently developed proton dose-buildup procedure is used for estimating doses. The model considers geomagnetic shielding, magnetic-storm conditions, spacecraft shielding, and body self-shielding. Inputs to the model include proton energy spectra, spacecraft orbital parameters, STS orbiter-shielding distribution at a given position, and a single parameter allowing for variation in breast size.

Shavers, Mark↗

Preliminary analysis of a radiobiological experiment for LifeSat

With the possibility of performing radiation life science experiments on a dedicated satellite (LifeSat) in space, a combined effort in radiation physics and radiation dosimetry, in addition to radiation biology, is clearly required to ensure that meaningful biological experiments can be performed. To better understand the relationship of these disciplines, some possible LifeSat missions are examined. As a trial biological system, tumorigenesis is considered in the Harderian gland of mice, a system of sufficient radiosensitivity for which relative biological effectiveness (RBE) is well defined by laboratory experiments.

Wilson, John W.↗

Interplanetary crew exposure estimates for the August 1972 and October 1989 solar particle events

Detailed exposure estimates for the bone marrow, ocular lens, and skin of astronauts on manned missions beyond the earth's magnetosphere have been made for the large solar particle events (SPE) of August 1972 and October 1989. The estimates were made using the coupled neutron-proton space radiation transport computer code BRYNTRN and the CAM model for the human body. It is found that at least 10 g/sq cm aluminum shielding is needed to keep estimated dose equivalent values below current space radiation exposure guidelines recommended for LEO missions. Space suits currently being designed will not provide adequate crew protection and may not even ensure crew survival in the event of exposure to a large SPE during extravehicular activity.

Townsend, Lawrence W.↗

Biological effectiveness of high-energy protons - Target fragmentation

High-energy protons traversing tissue produce local sources of high-linear-energy-transfer ions through nuclear fragmentation. The contribution of these target fragments to the biological effectiveness of high-energy protons using the cellular track model is examined. The effects of secondary ions are treated in terms of the production collision density using energy-dependent parameters from a high-energy fragmentation model. Calculations for mammalian cell cultures show that at high dose, at which intertrack effects become important, protons deliver damage similar to that produced by gamma rays, and with fragmentation the relative biological effectiveness (RBE) of protons increases moderately from unity. At low dose, where sublethal damage is unimportant, the contribution from target fragments dominates, causing the proton effectiveness to be very different from that of gamma rays with a strongly fluence-dependent RBE. At high energies, the nuclear fragmentation cross sections become independent of energy. This leads to a plateau in the proton single-particle-action cross section, below 1 keV/micron, since the target fragments dominate.

Cucinotta, Francis A.↗

Radiation exposure and dose estimates for a nuclear-powered manned Mars sprint mission

A conceptual manned mission to Mars is analyzed in order to estimate potential ionizing radiation doses that may be incurred by crew members during the course of the mission. The scenario is set for a journey during the solar active period and includes a brief stay on the Martian surface. Propulsion is assumed to be provided by nuclear thermal rocket power, and estimates of the dose contributions from the reactors are included. However, due to effective shielding of the reactors by large propellant tanks, it is found that the incurred doses are principally due to the charged particle natural environment. Recent data (August-December 1989) for large solar proton events are used to simulate the flame environment, while standard models are used for the trapped particle and galactic cosmic ray contributions. Shield effectiveness for several candidate materials are investigated.

Nealy, John E.↗

Space radiation dose analysis for solar flare of August 1989

Potential dose and dose rate levels to astronauts in deep space are predicted for the solar flare event which occurred during the week of August 13, 1989. The Geostationary Operational Environmental Satellite (GOES-7) monitored the temporal development and energy characteristics of the protons emitted during this event. From these data, differential fluence as a function of energy was obtained in order to analyze the flare using the Langley baryon transport code, BRYNTRN, which describes the interactions of incident protons in matter. Dose equivalent estimates for the skin, ocular lens, and vital organs for 0.5 to 20 g/sq cm of aluminum shielding were predicted. For relatively light shielding (less than 2 g/sq cm), the skin and ocular lens 30-day exposure limits are exceeded within several hours of flare onset. The vital organ (5 cm depth) dose equivalent is exceeded only for the thinnest shield (0.5 g/sq cm). Dose rates (rem/hr) for the skin, ocular lens, and vital organs are also computed.

Nealy, John E.↗

Energy deposition at the bone-tissue interface from nuclear fragments produced by high-energy nucleons

The transport of nuclear fragmentation recoils produced by high-energy nucleons in the region of the bone-tissue interface is considered. Results for the different flux and absorbed dose for recoils produced by 1 GeV protons are presented in a bidirectional transport model. The energy deposition in marrow cavities is seen to be enhanced by recoils produced in bone. Approximate analytic formulae for absorbed dose near the interface region are also presented for a simplified range-energy model.

Cucinotta, Francis A.↗