Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9
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Mussari, Christopher P.↗
Engineering topics
Watson, Andrew
Publications and source records attributed to Watson, Andrew.
A Linearized Model for Flicker and Contrast Thresholds at Various Retinal Illuminances
We previously proposed a flicker visibility metric for bright displays, based on psychophysical data collected at a high mean luminance. Here we extend the metric to other mean luminances. This extension relies on a linear relation between log sensitivity and critical fusion frequency, and a linear relation between critical fusion frequency and log retina lilluminance. Consistent with our previous metric, the extended flicker visibility metric is measured in just-noticeable differences (JNDs).
light adaptation↗
Tech Briefs Who's Who at NASA - Dr. Andrew Watson
Tech Briefs Article - Who's Who at NASA with Dr. Andrew (Beau) Watson. Includes podcast/transcript of full interview.
Garud, Sumedha↗
Visible Contrast Energy Metrics for Detection and Discrimination
Contrast energy was proposed by Watson, Robson, & Barlow as a useful metric for representing luminance contrast target stimuli because it represents the detectability of the stimulus in photon noise for an ideal observer. Like the eye, the ear is a complex transducer system, but relatively simple sound level meters are used to characterize sounds. These meters provide a range of frequency sensitivity functions and integration times depending on the intended use. We propose here the use of a range of contrast energy measures with different spatial frequency contrast sensitivity weightings, eccentricity sensitivity weightings, and temporal integration times. When detection threshold are plotting using such measures, the results show what the eye sees best when these variables are taken into account in a standard way. The suggested weighting functions revise the Standard Spatial Observer for luminance contrast detection and extend it into the near periphery. Under the assumption that the detection is limited only by internal noise, discrimination performance can be predicted by metrics based on the visible energy of the difference images
Ahumada, Albert↗
The Cortex Transform as an image preprocessor for sparse distributed memory: An initial study
An experiment is described which was designed to evaluate the use of the Cortex Transform as an image processor for Sparse Distributed Memory (SDM). In the experiment, a set of images were injected with Gaussian noise, preprocessed with the Cortex Transform, and then encoded into bit patterns. The various spatial frequency bands of the Cortex Transform were encoded separately so that they could be evaluated based on their ability to properly cluster patterns belonging to the same class. The results of this study indicate that by simply encoding the low pass band of the Cortex Transform, a very suitable input representation for the SDM can be achieved.
Olshausen, Bruno↗