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Schimmerling, Walter

Publications and source records attributed to Schimmerling, Walter.

The Health Risks of Extraterrestrial Environments (THREE) 2019 Annual Report

THREE is an encyclopedic website (http://three.jsc.nasa.gov) about the space radiation environment and its health risks to humans. The goal for the site is threefold: 1. to serve as a starting point for researchers new to either space, radiation, or both; 2. to serve as a source of useful information for established investigators; 3. to serve as a teaching tool for students; and, 4. to serve as a NASA reference source on all scientific aspects of space radiation and health. THREE is funded by the Space Radiation (SR) Element within NASA’s Human Research Program (HRP). The THREE Editorial Board is responsible for oversight of the content and policies for the website. The website is hosted by the NASA Johnson Space Center.

Schimmerling, Walter

Overview of NASA's space radiation research program

NASA is developing the knowledge required to accurately predict and to efficiently manage radiation risk in space. The strategy employed has three research components: (1) ground-based simulation of space radiation components to develop a science-based understanding of radiation risk; (2) space-based measurements of the radiation environment on planetary surfaces and interplanetary space, as well as use of space platforms to validate predictions; and, (3) implementation of countermeasures to mitigate risk. NASA intends to significantly expand its support of ground-based radiation research in line with completion of the Booster Applications Facility at Brookhaven National Laboratory, expected in summer of 2003. A joint research solicitation with the Department of Energy is under way and other interagency collaborations are being considered. In addition, a Space Radiation Initiative has been submitted by the Administration to Congress that would provide answers to most questions related to the International Space Station within the next 10 years.

NASA Discipline Radiation Health

Visualization of particle flux in the human body on the surface of Mars

For a given galactic cosmic ray (GCR) environment, information on the particle flux of protons, alpha particles, and heavy ions, that varies with respect to the topographical altitude on the Martian surface, are needed for planning exploration missions to Mars. The Mars Global Surveyor (MGS) mission with its Mars Orbiter Laser Altimeter (MOLA) instrument has been providing precise topographical surface map of the Mars. With this topographical data, the particle flux at the Martian surface level through the CO2 atmospheric shielding for solar minimum and solar maximum conditions are calculated. These particle flux calculations are then transported first through an anticipated shielding of a conceptual shelter with several water equivalent shield values (up to 50 g/cm2 of water in steps of 5 g/cm2) considered to represent a surface habitat, and then into the human body. Model calculations are accomplished utilizing the HZETRN, QMSFRG, and SUM-MARS codes. Particle flux calculations for 12 different locations in the human body were considered from skin depth to the internal organs including the blood-forming organs (BFO). Visualization of particle flux in the human body at different altitudes on the Martian surface behind a known shielding is anticipated to provide guidance for assessing radiation environment risk on the Martian surface for future human missions.

NASA Center JSC

Space Radiation Cancer Risk Projections for Exploration Missions: Uncertainty Reduction and Mitigation

In this paper we discuss expected lifetime excess cancer risks for astronauts returning from exploration class missions. For the first time we make a quantitative assessment of uncertainties in cancer risk projections for space radiation exposures. Late effects from the high charge and energy (HZE) ions present in the galactic cosmic rays including cancer and the poorly understood risks to the central nervous system constitute the major risks. Methods used to project risk in low Earth orbit are seen as highly uncertain for projecting risks on exploration missions because of the limited radiobiology data available for estimating HZE ion risks. Cancer risk projections are described as a product of many biological and physical factors, each of which has a differential range of uncertainty due to lack of data and knowledge. Monte-Carlo sampling from subjective error distributions represents the lack of knowledge in each factor to quantify risk projection overall uncertainty. Cancer risk analysis is applied to several exploration mission scenarios. At solar minimum, the number of days in space where career risk of less than the limiting 3% excess cancer mortality can be assured at a 95% confidence level is found to be only of the order of 100 days.

Cucinotta, Francis

End-To-End Risk Assesment: From Genes and Protein to Acceptable Radiation Risks for Mars Exploration

The human exploration of Mars will impose unavoidable health risks from galactic cosmic rays (GCR) and possibly solar particle events (SPE). It is the goal of NASA's Space Radiation Health Program to develop the capability to predict health risks with significant accuracy to ensure that risks are well below acceptable levels and to allow for mitigation approaches to be effective at reasonable costs. End-to-End risk assessment is the approach being followed to understand proton and heavy ion damage at the molecular, cellular, and tissue levels in order to predict the probability of the major health risk including cancer, neurological disorders, hereditary effects, cataracts, and acute radiation sickness and to develop countermeasures for mitigating risks.

Cucinotta, Francis A.

Effects of radiobiological uncertainty on vehicle and habitat shield design for missions to the moon and Mars

Some consequences of uncertainties in radiobiological risk due to galactic cosmic ray (GCR) exposure are analyzed for their effect on engineering designs for the first lunar outpost and a mission to explore Mars. This report presents the plausible effect of biological uncertainties, the design changes necessary to reduce the uncertainties to acceptable levels for a safe mission, and an evaluation of the mission redesign cost. Estimates of the amount of shield mass required to compensate for radiobiological uncertainty are given for a simplified vehicle and habitat. The additional amount of shield mass required to provide a safety factor for uncertainty compensation is calculated from the expected response to GCR exposure. The amount of shield mass greatly increases in the estimated range of biological uncertainty, thus, escalating the estimated cost of the mission. The estimates are used as a quantitative example for the cost-effectiveness of research in radiation biophysics and radiation physics.

Wilson, John W.

Effects of radiobiological uncertainty on shield design for a 60-day lunar mission

Some consequences of uncertainties in radiobiological risk due to galactic cosmic ray exposure are analyzed to determine their effect on engineering designs for a first lunar outpost - a 60-day mission. Quantitative estimates of shield mass requirements as a function of a radiobiological uncertainty factor are given for a simplified vehicle structure. The additional shield mass required for compensation is calculated as a function of the uncertainty in galactic cosmic ray exposure, and this mass is found to be as large as a factor of 3 for a lunar transfer vehicle. The additional cost resulting from this mass is also calculated. These cost estimates are then used to exemplify the cost-effectiveness of research.

Wilson, John W.

Transport methods and interactions for space radiations

This report presents a brief history leading to the involvement of the Langley Research Center of the National Aeronautics and Space Administration (NASA) in space-radiation physics and protection. Indeed, a relatively complete summary of technical capability as of the summer of 1990 is given. The Boltzmann equations for coupled ionic and neutronic fields are presented and inversion techniques for the Boltzmann operator are discussed. Errors generated by the straight ahead approximation are derived and are shown to be negligible for most problems of space-radiation protection. A decoupling of projectile propagation from the target fields greatly simplifies the Boltzmann equations and allows an analytic solution of the target fragment transport. Analytic and numerical methods of solving the projectile transport equations are discussed. The nuclear physics underlying the coefficients in the Boltzmann equation is discussed. A coupled-channel optical model is found as a consequence of the loose binding of nuclear matter and closure of the nuclear states in high-energy reactions. Transport solutions with the developed data base are used with laboratory experiments to validate both the transport code and the data base. Numerical benchmarks and comparison with Monte Carlo calculations are also used for code validation.

Wilson, John W.

The NASA Radiation Health Program

The Space Radiation Health Program (SRHP) is defined in terms of motivation and methodology with specific reference given to the impacts of HZE particles and solar energetic particles. The biological hazards are mentioned that can be associated with the two particle types and ionizing radiation in general. The lack of data on the impact of such radiation and effective shielding countermeasures is identified as the primary motivation for worst-case assumptions. However, the resulting shielding designs can potentially overestimate the thickness by a factor of 10 and add unnecessarily to vehicle take-off mass. A space-based validation system is proposed to complement ground-based investigations of the effects of ionizing radiation in interplanetary space. The Lifesat satellite is proposed as a part of the SRHP effort to determine the requirements for protection and future shielding specifications.

Schimmerling, Walter

Preliminary analysis of a radiobiological experiment for LifeSat

With the possibility of performing radiation life science experiments on a dedicated satellite (LifeSat) in space, a combined effort in radiation physics and radiation dosimetry, in addition to radiation biology, is clearly required to ensure that meaningful biological experiments can be performed. To better understand the relationship of these disciplines, some possible LifeSat missions are examined. As a trial biological system, tumorigenesis is considered in the Harderian gland of mice, a system of sufficient radiosensitivity for which relative biological effectiveness (RBE) is well defined by laboratory experiments.

Wilson, John W.

The HZE radiation problem

Radiation-exposure limits have yet to be established for missions envisioned in the framework of the Space Exploration Initiative. The radiation threat outside the earth's magnetosphere encompasses protons from solar particle events and the highly charged energetic particles constituting galactic cosmic rays; radiation biology entails careful consideration of the extremely nonuniform patterns of such particles' energy deposition. The ability to project such biological consequences of exposure to energetic particles as carcinogenicity currently involves great uncertainties from: (1) different regions of space; (2) the effects of spacecraft structures; and (3) the dose-effect relationships of single traversals of energetic particles.

Schimmerling, Walter

Biophysical aspects of heavy ion interactions in matter

The biological effects of high energy, high charge nuclei (HZE particles) occupy a central role in the management of space radiation hazards due to galactic cosmic rays. For the energy range of interest, the mean free path for nuclear interactions of these heavy ions is comparable to the thickness of the material traversed, and a significant fraction of stopping particles will undergo a nuclear reaction with the nuclei of the stopping material. Transport methods for HZE particles are dependent on models of the interaction of man-made systems with the space environment to an even greater extent than methods used for other types of radiation. Hence, there is a major need to validate these transport codes by comparison with experimental data. The basic physical properties of HZE particles will be reviewed and illustrated with the results of nuclear fragmentation experiments performed with 670A MeV neon ions incident on a water absorber and with measurements of multiple Coulomb scattering of uranium beams in copper. Finally, the extent to which physical measurements yield radiobiological predictions is illustrated for the example of neon.

Schimmerling, Walter

Studies of HZE particle interactions and transport for space radiation protection purposes

The main emphasis is on developing general methods for accurately predicting high-energy heavy ion (HZE) particle interactions and transport for use by researchers in mission planning studies, in evaluating astronaut self-shielding factors, and in spacecraft shield design and optimization studies. The two research tasks are: (1) to develop computationally fast and accurate solutions to the Boltzmann (transport) equation; and (2) to develop accurate HZE interaction models, from fundamental physical considerations, for use as inputs into these transport codes. Accurate solutions to the HZE transport problem have been formulated through a combination of analytical and numerical techniques. In addition, theoretical models for the input interaction parameters are under development: stopping powers, nuclear absorption cross sections, and fragmentation parameters.

Townsend, Lawrence W.