Long-term ambient sulfur dioxide exposure during gestation and preterm birth in North Carolina, 2003–2015
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Engineering topics
Publications and source records attributed to Richardson, David.
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Model-Based Systems Engineering (MBSE) is the formalized application of modeling to support system requirements, design, analysis, verification and validation activities beginning in the conceptual design phase and continuing throughout development and later life cycle phases . This presentation will discuss the value proposition that MBSE has for Systems Engineering, and the associated culture change needed to adopt it.
Differential drag is a technique for altering the semimajor axis, velocity, and along-track position of a spacecraft in low Earth orbit. It involves varying the spacecraft's cross-sectional area relative to its velocity direction by temporarily changing attitude and solar array angles, thus varying the amount of atmospheric drag on the spacecraft. The technique has recently been proposed and used by at least three satellite systems for initial separation of constellation spacecraft after launch, stationkeeping during the mission, and potentially for conjunction avoidance. Similarly, differential drag has been proposed as a control strategy for rendezvous, removing the need for active propulsion. In theory, some operational missions that lack propulsion capability could use this approach for conjunction avoidance, though options are typically constrained for spacecraft that are already in orbit. Shortly before the spacecraft was decommissioned, an experiment was performed using NASA's EO-1 spacecraft in order to demonstrate differential drag on an operational spacecraft in orbit, and discover some of the effects differential drag might manifest. EO-1 was not designed to maintain off-nominal orientations for long periods, and as a result the team experienced unanticipated challenges during the experiment. This paper will discuss operations limitations identified before the experiment, as well as those discovered during the experiment. The effective displacement that resulted from increasing the drag area for 39 hours will be compared to predictions as well as the expected position if the spacecraft maintained nominal operations. A hypothetical scenario will also be examined, studying the relative risks of maintaining an operational spacecraft bus in order to maintain the near-maximum drag area orientation and hasten reentry.
Differential drag is a technique for altering the semi-major axis, velocity, and along-track position of a spacecraft in low Earth orbit. It involves varying the spacecrafts cross-sectional area relative to its velocity direction by temporarily changing attitude and solar array angles, thus varying the amount of atmospheric drag on the spacecraft. The technique has recently been proposed and used by at least three satellite systems for initial separation of constellation spacecraft after launch, stationkeeping during the mission, and potentially for conjunction avoidance. Similarly, differential drag has been proposed as a control strategy for rendezvous, removing the need for active propulsion. In theory, some operational missions that lack propulsion capability could use this approach for conjunction avoidance, though options are typically constrained for spacecraft that are already in orbit. Shortly before the spacecraft was decommissioned, an experiment was performed using NASAs EO-1 spacecraft in order to demonstrate differential drag on an operational spacecraft in orbit, and discover some of the effects differential drag might manifest. EO-1 was not designed to maintain off-nominal orientations for long periods, and as a result the team experienced unanticipated challenges during the experiment. This paper will discuss operations limitations identified before the experiment, as well as those discovered during the experiment. The effective displacement that resulted from increasing the drag area for 39 hours will be compared to predictions as well as the expected position if the spacecraft maintained nominal operations. A hypothetical scenario will also be examined, studying the relative risks of maintaining an operational spacecraft bus in order to maintain the near-maximum drag area orientation and hasten reentry.
The x-ray crystal structure of Shewanella oneidensis OmcA, an extracellular decaheme cytochrome involved in mineral reduction, was solved to a resolution of 2.7 Å. The four OmcA molecules in the asymmetric unit were arranged so the distance between heme-5 on adjacent OmcA monomers was less than 1 nm, indicative of a transient OmcA dimer capable of intermolecular electron transfer. A previously identified hematite binding motif was identified near heme 10, forming a hydroxylated surface that would bring a heme-10 electron egress site to ~ 1 nm of mineral surface.
Respiratory and photosynthetic electron transfer chains are dependent on vectorial electron transfer through a series of redox proteins. Examples include electron transfer from NapC to NapAB nitrate reductase in Paracoccus denitrificans and from CymA to Fcc 3 (flavocytochrome c 3 ) fumarate reductase in Shewanella oneidensis MR-1. In the present article, we demonstrate that graphite electrodes can serve as surfaces for the stepwise adsorption of NapC and NapAB, and the stepwise adsorption of CymA and Fcc 3 . Aspects of the catalytic properties of these assemblies are different from those of NapAB and Fcc 3 adsorbed in isolation. We propose that this is due to the formation of NapC-NapAB and of CymA-Fcc 3 complexes that are capable of supporting vectorial electron transfer.
The mineral respiring bacterium Shewanella oneidensis uses a protein complex, MtrCAB, composed of two decaheme cytochromes brought together inside a transmembrane porin to transport electrons across the outer membrane to a variety of mineral-based electron acceptors. A proteoliposome system that contains methyl viologen as an internalised electron carrier has been used to investigate how the topology of the MtrCAB complex relates to its ability to transport electrons across a lipid bilayer to externally-located Fe(III) oxides. With MtrA facing the interior and MtrC exposed on the outer surface of the phospholipid bilayer, direct electron transfer from the interior through MtrCAB to solid-phase Fe(III) oxides was demonstrated. The observed rates of conduction through the protein complex were 2 to 3 orders of magnitude higher than that observed in whole cells, demonstrating that direct electron exchange between MtrCAB and Fe(III) oxides is efficient enough to support in-vivo, anaerobic, solid phase iron respiration.
This presentation provides an overview of the work done at ATK Launch Systems with and indication of how engineering knowledge can be applied to several real world problems. All material in the presentation has been screened to meet ITAR restrictions. The information provided is a compilation of general engineering knowledge and material available in the public domain. The presentation provides an overview of ATK Launch Systems and NASA programs. Some discussion is provided about the types of engineering conducted at the Promontory plant with added detail about RSRM nozzle engineering. Some brief examples of examples of nozzle technical issues with regard to adhesives and phenolics are shared. These technical issue discussions are based on material available in the public domain.
A temperature- and time-dependent mathematical model predicts the conditions for failure of a material subjected to multiaxial stress. The model was initially applied to a filled epoxy below its glass-transition temperature, and is expected to be applicable to other materials, at least below their glass-transition temperatures. The model is justified simply by the fact that it closely approximates the experimentally observed failure behavior of this material: The multiaxiality of the model has been confirmed (see figure) and the model has been shown to be applicable at temperatures from -20 to 115 F (-29 to 46 C) and to predict tensile failures of constant-load and constant-load-rate specimens with failure times ranging from minutes to months..