Ribosome-catalyzed polyester formation
Polyester formation by Escherichia coli ribosome catalyzed alpha-hydroxy acid incorporation into polymer chain
Engineering topics
Publications and source records attributed to Rich, A..
Polyester formation by Escherichia coli ribosome catalyzed alpha-hydroxy acid incorporation into polymer chain
High resolution X ray diffraction patterns of yeast phenylalanyl transfer RNA crystals, discussing double helical regional distribution characteristics
Demonstration that alpha-hydroxy acids may have participated in the formation of prebiological polymers in a manner similar to the participation of alpha-amino acids. Ex periments are described which indicate that the system for forming peptide bonds in present-day biological organisms is equally competent in forming ester and polyester bonds. In particular, the experiments described are directed toward answering questions regarding the action of peptidyl transferase in ester formation. Also, an attempt is made to determine whether a complete protein synthetic system can operate with transfer RNA molecules which have alpha-hydroxyl acids attached to them instead of alpha-amino acids, using both synthetic and natural mRNA. The ability of ribosomal peptidyl transferase to catalyze the formation of an ester bond as well as its normal product, the peptide bond, is demonstrated.
Orthorhombic form of crystalline formylmethionine transfer RNA, obtaining Patterson function from three dimensional X ray diffraction data
Hydrogen bonding of derivatives of guanosine and cytidine soluble in chloroform studied in IR, CONFIRMING geometrical specificity in two-stranded nucleic acids
Experiments for detection of life and chemical processing of Martian material
IR absorption bands in concentrated solutions of 9-ethyladenine or 1-cyclohexyluracil in deuterochloroform demonstrate hydrogen bonding of adenine and uracil derivatives with themselves