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Nguyen, H.

Publications and source records attributed to Nguyen, H..

At least 19 records

Quasielastic $\overrightarrow{^{3}He}$ $(\overrightarrow{e},e′)$ asymmetry in the threshold region with a longitudinally polarized target

We report on the measurements of the double-spin asymmetry from electron- 3 He scattering in the threshold region of two- and three-body breakup of 3 He for 4-momentum transfer values of 0.1 and 0.2 (GeV/c) 2 . The measurement was done at Jefferson Lab using a polarized 3 He target with its spin aligned parallel to the beam direction. This asymmetry is sensitive to a combination of spin-dependent response functions not previously measured and may highlight differences in two body forces, meson-exchange currents and final-state interactions. The results of this measurement serve as a test of our understanding of few-body systems. When compared with calculations from plane wave impulse approximation and Faddeev calculations, we found that the latter, which use modern nuclear potentials and prescriptions for meson-exchange currents, demonstrate an overall good agreement with data.

Few-body nuclei↗

Electro- and photoproduction of muon pairs with $$\mu $$CLAS12: double deeply virtual compton scattering, timelike compton scattering, and $$J/\psi $$ production

The CEBAF Large Acceptance Spectrometer for operation at 12 GeV (CLAS12) at the Thomas Jefferson National Accelerator Facility has played a central role in advancing the understanding of nucleon and nuclear structure. As increasingly precise data become available, new physics opportunities emerge that extend beyond the current capabilities of CLAS12. In this article, a program to explore the quark and gluon structure of the nucleon through di-muon electro- and photoproduction is presented. Its primary focus is the measurement of beam-spin asymmetries in Double Deeply Virtual Compton Scattering, . By independently varying the incoming and outgoing photon virtualities and momentum transfer, the DDVCS measurement provides access to the Generalized Parton Distributions over their full three-dimensional phase space, extending beyond the kinematic constraints of Deeply Virtual Compton Scattering and Timelike Compton Scattering. In addition, the large acceptance and high luminosity of the CLAS12 experiment will enable precision measurements of near-threshold production and high-statistics studies of Timelike Compton Scattering.

Alvarado, J. S.↗

Measurement of gravitational lensing of the cosmic microwave background using SPT-3G 2018 data

We present a measurement of gravitational lensing over 1500 deg 2 of the Southern sky using SPT-3G temperature data at 95 GHz and 150 GHz taken in 2018. The lensing amplitude relative to a fiducial Planck 2018 Lambda cold dark matter ( Λ CDM ) cosmology is found to be 1.020 ± 0.060 , excluding instrumental and astrophysical systematic uncertainties. We conduct extensive systematic and null tests to check the robustness of the lensing measurements, and report a minimum-variance combined lensing power spectrum over angular multipoles of 50 < L < 2000 , which we use to constrain cosmological models. When analyzed alone and jointly with primary cosmic microwave background (CMB) spectra within the Λ CDM model, our lensing amplitude measurements are consistent with measurements from SPT-SZ, SPTpol, ACT, and Planck. Incorporating loose priors on the baryon density and other parameters including uncertainties on a foreground bias template, we obtain a 1 σ constraint on σ 8 Ω m 0.25 = 0.595 ± 0.026 using the SPT-3G 2018 lensing data alone, where σ 8 is a common measure of the amplitude of structure today and Ω m is the matter density parameter. Combining SPT-3G 2018 lensing measurements with baryon acoustic oscillation (BAO) data, we derive parameter constraints of σ 8 = 0.810 ± 0.033 , S 8 ≡ σ 8 ( Ω m / 0.3 ) 0.5 = 0.836 ± 0.039 , and Hubble constant H 0 = 68.8 - 1.6 + 1.3 km s - 1 Mpc - 1 . Our preferred S 8 value is higher by 1.6 to 1.8 σ compared to cosmic shear measurements from DES-Y3, HSC-Y3, and KiDS-1000 at lower redshift and smaller scales. We combine our lensing data with CMB anisotropy measurements from both SPT-3G and Planck to constrain extensions of Λ CDM . Using CMB anisotropy and lensing measurements from SPT-3G only, we provide independent constraints on the spatial curvature of Ω K = 0.01 4 - 0.026 + 0.023 (95% C.L.) and the dark energy density of Ω Λ = 0.72 2 - 0.026 + 0.031 (68% C.L.). When combining SPT-3G lensing data with SPT-3G CMB anisotropy and BAO data, we find an upper limit on the sum of the neutrino masses of ∑ m ν < 0.30 eV (95% C.L.). Due to the different combination of angular scales and sky area, this lensing analysis provides an independent check on lensing measurements by ACT and Planck.

79 ASTRONOMY AND ASTROPHYSICS↗

Twin Boundaries Contribute to The First Cycle Irreversibility of LiNiO 2

Abstract LiNiO 2 remains a target for layered oxide Li‐ion cathode development as it can theoretically deliver the highest energy density of this materials class. In practice, LiNiO 2 suffers from poor capacity retention due to electrochemically‐induced structural changes. While the impact of Ni off‐stoichiometry on the electrochemical performance has been extensively studied, that of planar defects present in the as‐synthesized cathode is not well understood. Advanced ex situ and operando structure probes are used to identify and quantify point and planar defects present in as‐synthesized Li 1‐y Ni 1+y O 2 cathodes and monitor their evolution during the first cycle. Specifically, a 7 Li nuclear magnetic resonance (NMR) signature characteristic of Li environments near twin boundaries is identified; an assignment supported by first‐principles calculations and scanning transmission electron microscopy (STEM) images of twin boundary defects. The NMR results suggest that the concentration of twin boundaries depends on the amount of Ni excess. Moreover, operando magnetometry and ex situ synchrotron X‐ray diffraction and NMR demonstrate that these planar defects impede Li reinsertion into the bulk cathode at reasonable discharge rates and contribute to the first cycle irreversible capacity. These findings provide new design rules for Li 1‐y Ni 1+y O 2 cathodes, whereby a reduced concentration of twin boundaries in the pristine material leads to reduced kinetic limitations and improved cathode utilization.

Nguyen, H.↗

Robust deep learning–based protein sequence design using ProteinMPNN

Although deep learning has revolutionized protein structure prediction, almost all experimentally characterized de novo protein designs have been generated using physically based approaches such as Rosetta. Here, we describe a deep learning–based protein sequence design method, ProteinMPNN, that has outstanding performance in both in silico and experimental tests. On native protein backbones, ProteinMPNN has a sequence recovery of 52.4% compared with 32.9% for Rosetta. The amino acid sequence at different positions can be coupled between single or multiple chains, enabling application to a wide range of current protein design challenges. We demonstrate the broad utility and high accuracy of ProteinMPNN using x-ray crystallography, cryo–electron microscopy, and functional studies by rescuing previously failed designs, which were made using Rosetta or AlphaFold, of protein monomers, cyclic homo-oligomers, tetrahedral nanoparticles, and target-binding proteins.

59 BASIC BIOLOGICAL SCIENCES↗

Asteroid Measurements at Millimeter Wavelengths with the South Pole Telescope

Abstract We present the first measurements of asteroids in millimeter wavelength data from the South Pole Telescope (SPT), which is used primarily to study the cosmic microwave background (CMB). We analyze maps of two ∼270 deg2 sky regions near the ecliptic plane, each observed with the SPTpol camera ∼100 times over 1 month. We subtract the mean of all maps of a given field, removing static sky signal, and then average the mean-subtracted maps at known asteroid locations. We detect three asteroids—(324) Bamberga, (13) Egeria, and (22) Kalliope—with signal-to-noise ratios (S/N) of 11.2, 10.4, and 6.1, respectively, at 2.0 mm (150 GHz); we also detect (324) Bamberga with an S/N of 4.1 at 3.2 mm (95 GHz). We place constraints on these asteroids’ effective emissivities, brightness temperatures, and light-curve modulation amplitude. Our flux density measurements of (324) Bamberga and (13) Egeria roughly agree with predictions, while our measurements of (22) Kalliope suggest lower flux, corresponding to effective emissivities of 0.64 ± 0.11 at 2.0 and < 0.47 at 3.2 mm. We predict the asteroids detectable in other SPT data sets and find good agreement with detections of (772) Tanete and (1093) Freda in recent data from the SPT-3G camera, which has ∼10× the mapping speed of SPTpol. This work is the first focused analysis of asteroids in data from CMB surveys, and it demonstrates we can repurpose historic and future data sets for asteroid studies. Future SPT measurements can help constrain the distribution of surface properties over a larger asteroid population.

79 ASTRONOMY AND ASTROPHYSICS↗

The Design and Integrated Performance of SPT-3G

Abstract SPT-3G is the third survey receiver operating on the South Pole Telescope dedicated to high-resolution observations of the cosmic microwave background (CMB). Sensitive measurements of the temperature and polarization anisotropies of the CMB provide a powerful data set for constraining cosmology. Additionally, CMB surveys with arcminute-scale resolution are capable of detecting galaxy clusters, millimeter-wave bright galaxies, and a variety of transient phenomena. The SPT-3G instrument provides a significant improvement in mapping speed over its predecessors, SPT-SZ and SPTpol. The broadband optics design of the instrument achieves a 430 mm diameter image plane across observing bands of 95, 150, and 220 GHz, with 1.2′ FWHM beam response at 150 GHz. In the receiver, this image plane is populated with 2690 dual-polarization, trichroic pixels (∼16,000 detectors) read out using a 68× digital frequency-domain multiplexing readout system. In 2018, SPT-3G began a multiyear survey of 1500 deg 2 of the southern sky. We summarize the unique optical, cryogenic, detector, and readout technologies employed in SPT-3G, and we report on the integrated performance of the instrument.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Constraints on Λ CDM extensions from the SPT-3G 2018 $EE$ and $TE$ power spectra

Here, we present constraints on extensions to the Λ CDM cosmological model from measurements of the E-mode polarization autopower spectrum and the temperature-E-mode cross-power spectrum of the cosmic microwave background (CMB) made using 2018 SPT-3G data. The extensions considered vary the primordial helium abundance, the effective number of relativistic degrees of freedom, the sum of neutrino masses, the relativistic energy density and mass of a sterile neutrino, and the mean spatial curvature. We do not find clear evidence for any of these extensions, from either the SPT-3G 2018 dataset alone or in combination with baryon acoustic oscillation and Planck data. None of these model extensions significantly relax the tension between Hubble-constant, H 0 , constraints from the CMB and from distance-ladder measurements using Cepheids and supernovae. The addition of the SPT-3G 2018 data to Planck reduces the square-root of the determinants of the parameter covariance matrices by factors of 1.3–2.0 across these models, signaling a substantial reduction in the allowed parameter volume. We also explore CMB-based constraints on H 0 from combined SPT, Planck, and ACT DR4 datasets. While individual experiments see some indications of different H 0 values between the TT, TE, and EE spectra, the combined H 0 constraints are consistent between the three spectra. For the full combined datasets, we report H 0 = 67.49 ± 0.53 km s -1 Mpc -1 , which is the tightest constraint on H0 from CMB power spectra to date and in 4.1σ tension with the most precise distance-ladder-based measurement of H 0 . The SPT-3G survey is planned to continue through at least 2023, with existing maps of combined 2019 and 2020 data already having ~ 3.5 x lower noise than the maps used in this analysis.

79 ASTRONOMY AND ASTROPHYSICS↗

Detection of Galactic and Extragalactic Millimeter-wavelength Transient Sources with SPT-3G

High angular resolution cosmic microwave background experiments provide a unique opportunity to conduct a survey of time-variable sources at millimeter wavelengths, a population that has primarily been understood through follow-up measurements of detections in other bands. Here we report the first results of an astronomical transient survey with the South Pole Telescope (SPT) using the SPT-3G camera to observe 1500 deg 2 of the southern sky. The observations took place from 2020 March to November in three bands centered at 95, 150, and 220 GHz. This survey yielded the detection of 15 transient events from sources not previously detected by the SPT. The majority are associated with variable stars of different types, expanding the number of such detected flares by more than a factor of two. Additionally, the stellar flares are unpolarized and bright, in some cases exceeding 1 Jy, and have durations from a few minutes to several hours. Another population of detected events last for 2–3 weeks and appear to be extragalactic in origin. Though data availability at other wavelengths is limited, we find evidence for concurrent optical activity for two of the stellar flares. Future data from SPT-3G and forthcoming instruments will provide real-time detection of millimeter-wave transients on timescales of minutes to months.

79 ASTRONOMY AND ASTROPHYSICS↗