The mitochondria-targeted peptide SS-31 binds lipid bilayers and modulates surface electrostatics as a key component of its mechanism of action
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99 GENERAL AND MISCELLANEOUS↗
Engineering topics
May, E.
Publications and source records attributed to May, E..
Fermilab Test Beam Facility Annual Report: FY19
This Technical Memorandum (TM) summarizes the Fermilab Test Beam Faciltiy (FTBF) operations for FY2019. It is one of a series of annual publications intended to gather information in one place. This TM discusses the experiments performed at the Test Beam from November 2018 to July 2019. The experiments are listed in Table 1. Each experiment wrote a summary that was edited for clarity and is included in this report.
43 PARTICLE ACCELERATORS↗
MCP-PMT development at Argonne for particle identification
The proposed high-energy high-luminosity polarized Electron-Ion Collider (EIC) demands excellent particle identification over a wide range of particles momenta to achieve the best separation between signal and background particles. Various Cherenkov imaging detector sub-systems are being considered in EIC detector concepts for hadron identification for particles momenta up to 50 GeV/c. One important challenge in this case is to provide a reliable highly pixelated photosensor working in the high radiation and high magnetic field environment. The recently commercialized Large Area Picosecond Photo-Detector (LAPPD) provides a promising low-cost photosensor solution for the various EIC Cherenkov imaging sub-systems. Optimization of the phtosensor design for high magnetic field tolerance, precision timing resolution, and pixelated readout was performed at Argonne National Laboratory with 6 x 6 cm(2) microchannel plate photomultipliers. The techniques and optimized design parameters would be transferrable to industrial partners for low-cost LAPPD production to achieve the demonstrated performance.
atomic layer deposition↗
Multi-Anode Square Microchannel Plate Photomultiplier Tube
Photek has developed a high performance 4096-anode photomultiplier tube using microchannel plates as the gain medium. Additionally, the detector has been designed in a square format to maximise the active area and allow for easy tiling to cover large areas using multiple units. This paper analyses the detector performance in terms of gain and photocathode uniformity, single photon timing accuracy, count rate capability, cross talk and magnetic field susceptibility.
47 OTHER INSTRUMENTATION↗
Structure basis of protein kinase R autophosphorylation
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99 GENERAL AND MISCELLANEOUS↗
Database computing in HEP
The major SSC experiments are expected to produce up to 1 Petabyte of data per year each. Once the primary reconstruction is completed by farms of inexpensive processors, I/O becomes a major factor in further analysis of the data. We believe that the application of database techniques can significantly reduce the I/O performed in these analyses. We present examples of such I/O reductions in prototypes based on relational and object-oriented databases of CDF data samples.
Day, C. T.↗