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Lowe, Christopher

Publications and source records attributed to Lowe, Christopher.

Toward Computation-Guided Design of Tunable Organic-Inorganic CdS Quantum Dot Binary Superlattices

Combining the advantages of structural programmability in sequence-defined biomimetic molecules and the controllable packing geometry in nanoparticle superlattices, we demonstrate a self-assembled organic-inorganic superlattice whose structure can be altered with the slightest change in the sequence of the organic counterpart. Here, oleate-coated CdS quantum dots (QDs) form a square-packed superlattice with a 1:1 molar equivalence of a di-block amphiphilic peptoid (Nbrpe6Dig) in chloroform. In contrast, no apparent structure is observed in the organic solvent alone. Based on theoretical evidence, we show that the assembly is a binary superlattice where both the CdS QDs and the peptoids serve as building blocks and further predict a correlation between the superlattice structure and the peptoid sequence. The computationally guided prediction is validated by experiments where superlattice transformation is observed with modified peptoids. The mechanism identified in our work inspires new ways to control and tune organic-inorganic hybrid nanomaterial self-assembly.

Qi, Xin↗

Electromagnetic Compatibility Considerations for International Space Station Payload Developers

The International Space Station (ISS) is a laboratory for scientific research, innovative technology development, and global education. The ISS provides a number of facilities and platforms for payload developers and investigators to conduct biological, microgravity, and Earth and space observation science, as well as for performing technology development. Due to the unique nature of the ISS vehicle and its electrical power and data systems, achieving electromagnetic compatibility (EMC) with the vehicle requires special considerations by the payload developer. The ISS electromagnetic interference (EMI) requirements and test methods are based on MIL-STD-461, “Electromagnetic Emissions and Susceptibility Requirements for the Control of Electromagnetic Interference”, Revision C, and MIL-STD-462, “Electromagnetic Interference Characteristics, Measurement of,” respectively. The low source impedance of the test setup requires special considerations when designing or selecting EMI power filters and switched mode power supplies. Many filters, suited for later revisions of MIL-STD-461, will result in non-compliant designs. ISS electrical power system power quality requirements, imposed to protect the stability of the system, can also affect EMI filter design. The selection and use of commercial-off-the-shelf (COTS) equipment for ISS applications requires special considerations to meet both EMC and crew safety requirements. Furthermore, the ISS environment can provide unique immunity challenges; if the payload developer ignores these challenges, the result is a possible loss of science or impact to technology demonstration. The ISS provides a unique opportunity for the science and technology development community. However, in order to be successful, the payload developer must incorporate special EMC considerations, many of which will be presented.

McCollum, Matthew↗

Hemichordates and the origin of chordates

Hemichordates, the phylum of bilateral animals most closely related to chordates, could reveal the evolutionary origins of chordate traits such as the nerve cord, notochord, gill slits and tail. The anteroposterior maps of gene expression domains for 38 genes of chordate neural patterning are highly similar for hemichordates and chordates, even though hemichordates have a diffuse nerve-net. About 40% of the domains are not present in protostome maps. We propose that this map, the gill slits and the tail date to the deuterostome ancestor. The map of dorsoventral expression domains, centered on a Bmp-Chordin axis, differs between the two groups; hemichordates resemble protostomes more than they do chordates. The dorsoventral axis might have undergone extensive modification in the chordate line, including centralization of the nervous system, segregation of epidermis, derivation of the notochord, and an inversion of organization.

Review, Tutorial↗