Chemically stable fluorescent proteins for advanced microscopy
Explore the source record for details and available documents.
Campbell, Benjamin C.↗
Engineering topics
Looger, Loren L.
Publications and source records attributed to Looger, Loren L..
Computerized in vitro test for chemical toxicity based on tetrahymena swimming patterns
An apparatus and method for rapidly determining chemical toxicity was evaluated. The toxicity monitor includes an automated scoring of how motile biological cells (Tetrahymena pyriformis) slow down or otherwise change their swimming patterns in a hostile chemical environment. The device, called the Motility Assay Apparatus (MAA) is tested for 30 second determination of chemical toxicity in 20 aqueous samples containing trace organics and salts. With equal or better detection limits, results compare favorably to in vivo animal tests of eye irritancy, in addition to agreeing for all chemicals with previous manual evaluations of single cell motility.
Noever, David A.↗
Computerized In Vitro Test for Chemical Toxicity Based on Tetrahymena Swimming Patterns
An apparatus and a method for rapidly determining chemical toxicity have been evaluated as an alternative to the rabbit eye initancy test (Draize). The toxicity monitor includes an automated scoring of how motile biological cells (Tetrahymena pyriformis) slow down or otherwise change their swimming patterns in a hostile chemical environment. The method, called the motility assay (MA), is tested for 30 s to determine the chemical toxicity in 20 aqueous samples containing trace organics and salts. With equal or better detection limits, results compare favorably to in vivo animal tests of eye irritancy.
Noever, David A.↗