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Lewis, S. M.

Publications and source records attributed to Lewis, S. M..

New Horizons: Scalar and Vector Ultralight Dark Matter

The last decade has seen unprecedented effort in dark matter model building at all mass scales coupled with the design of numerous new detection strategies. Transformative advances in quantum technologies have led to a plethora of new high-precision quantum sensors and dark matter detection strategies for ultralight ($<10\,$eV) bosonic dark matter that can be described by an oscillating classical, largely coherent field. This white paper focuses on searches for wavelike scalar and vector dark matter candidates.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Axion Dark Matter

Axions are well-motivated dark matter candidates with simple cosmological production mechanisms. They were originally introduced to solve the strong CP problem, but also arise in a wide range of extensions to the Standard Model. This Snowmass white paper summarizes axion phenomenology and outlines next-generation laboratory experiments proposed to detect axion dark matter. There are vibrant synergies with astrophysical searches and advances in instrumentation including quantum-enabled readout, high-Q resonators and cavities and large high-field magnets. This white paper outlines a clear roadmap to discovery, and shows that the US is well-positioned to be at the forefront of the search for axion dark matter in the coming decade.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Continuous distributions of specific ventilation recovered from inert gas washout

A new technique is described for recovering continuous distributions of ventilation as a function of tidal ventilation/volume ratio from the nitrogen washout. The analysis yields a continuous distribution of ventilation as a function of tidal ventilation/volume ratio represented as fractional ventilations of 50 compartments plus dead space. The procedure was verified by recovering known distributions from data to which noise had been added. Using an apparatus to control the subject's tidal volume and FRC, mixed expired N2 data gave the following results: (a) the distributions of young, normal subjects were narrow and unimodal; (b) those of subjects over age 40 were broader with more poorly ventilated units; (c) patients with pulmonary disease of all descriptions showed enlarged dead space; (d) patients with cystic fibrosis showed multimodal distributions with the bulk of the ventilation going to overventilated units; and (e) patients with obstructive lung disease fell into several classes, three of which are illustrated.

Lewis, S. M.↗

Emptying patterns of the lung studied by multiple-breath N2 washout

Changes in the nitrogen concentration seen during the single-breath nitrogen washout reflect changes in relative flow (ventilation) from units with differing ventilation/volume ratios. The multiple-breath washout provides sufficient data on ventilation for units with varying ventilation/volume ratios to be plotted as a function of the volume expired. Flow from the dead space may also be determined. In young normals the emptying patterns are narrow and unimodal throughout the alveolar plateau with little or no flow from the dead space at the end of the breath. Older normals show more flow from the dead space, particularly toward the end of the breath, and some show a high ventilation/volume ratio mode early in the breath. Patients with obstructive lung disease have a high flow from the dead space which is present throughout the breath. A well ventilated mode at the end of the breath is seen in some obstructed subjects. Patients with cystic fibrosis showed a poorly ventilated mode appearing at the end of the breath as well as a very high dead space.

Lewis, S. M.↗