Discovery of A-910, a Highly Potent and Orally Bioavailable Dual MerTK/Axl-Selective Tyrosine Kinase Inhibitor
Not provided.
Pharmacology & Pharmacy↗
Engineering topics
Lee, Hyung
Publications and source records attributed to Lee, Hyung.
High Repetition Rate Pulsed 2-Micron Laser Transmitter for Coherent CO2 DIAL Measurement
A high repetition rate, highly efficient, Q-switched 2-micron laser system as the transmitter of a coherent differential absorption lidar for CO2 measurement has been developed at NASA Langley Research Center. Such a laser transmitter is a master-slave laser system. The master laser operates in a single frequency, either on-line or off-line of a selected CO2 absorption line. The slave laser is a Q-switched ring-cavity Ho:YLF laser which is pumped by a Tm:fiber laser. The repetition rate can be adjusted from a few hundred Hz to 10 kHz. The injection seeding success rate is from 99.4% to 99.95%. For 1 kHz operation, the output pulse energy is 5.5mJ with the pulse length of approximately 50 ns. The optical-to-optical efficiency is 39% when the pump power is 14.5W. The measured standard deviation of the laser frequency jitter is about 3 MHz.
Singh, Uprendra N.↗
Proton and Gamma Radiation Effects in Undoped, Single-doped and co-doped YLiF4 and LuLiF4
Proton and gamma radiation effects in various YLiF4 and LuLiF4 crystals have been investigated. The radiation induced color centers compared with six different kinds of crystal samples in ranges up to 200 krads and 200 MeV. The radiation induced absorption coefficients are strongly dependent on polarization and concentration of rare-earth ions.
Lee, Hyung↗
High Repetition Rate and Frequency Stabilized Ho:YLF Laser for CO2 Differential Absorption Lidar
High repetition rate operation of an injection seeded Ho:YLF laser has been demonstrated. For 1 kHz operation, the output pulse energy reaches 5.8mJ and the optical-to-optical efficiency is 39% when the pump power is 14.5W.
Bai, Yingxin↗
Conductively Cooled Ho:Tm:LuLiF Laser Amplifier
A conductively-cooled Ho:Tm:LuLiF laser head can amplify 80mJ/340ns probe pulses into 400mJ when the pump pulse energy is close to amplified spontaneous emission (ASE) threshold, 5.6J. For a small signal, the double-pass amplification exceeds 25.
Bai, Yingxin↗
Efficient Operation of Conductively Cooled Ho:Tm:LuLiF Laser Oscillator/Amplifier
A conductively-cooled Ho:Tm:LuLiF laser oscillator generates 1.6J normal mode pulses at 10Hz with optical to optical efficiency of 20%. When the laser head module is used as the amplifier, the double-pass small-signal amplification excesses 25.
Yu, Jirong↗
Highly Efficient Q-switched Ho:YLF Laser Pumped by Tm:Fiber Laser
A highly efficient Q-switched Ho:YLF laser pumped by a Tm:fiber laser has been designed and demonstrated. When the pump power is 30 W, the pulse energy is 30mJ at the repetition rate of 100Hz.
Yu, Jirong↗
Injection Seeded/Phase-Conjugated 2-micron Laser System
For the first time, beam quality improvement of 2 micron laser using a fiber based phase conjugation mirror has been demonstrated. Single frequency operation is necessary to lower threshold. The reflectivity of PCM is approx. 50%.
Bai, Yingxin↗
Highly Efficient Operation of Tm:fiber Laser Pumped Ho:YLF Laser
A 19 W, TEM(sub 00) mode, Ho:YLF laser pumped by continuous wave Tm:fiber laser has been demonstrated at the room temperature. The slope efficiency and optical-to-optical efficiency are 65% and 55%, respectively.
Bai, Yingxin↗