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Larkin, Ariana Kayla

Publications and source records attributed to Larkin, Ariana Kayla.

Rad-Hard SBC: Radiation-Hardened Single-Board Computer

As global reliance on satellites and their services increases, scientists and engineers will continue to feel pressure to reduce costs, save power, and reduce size and weight. Los Alamos researchers have developed the Rad-Hard SBC to alleviate this pressure. The invention is a radiation- and mechanically-hardened single-board computer that is small, lightweight, and uses less power than any commercially available space-grade computer. Rad-Hard SBC provides an affordable option for long-lasting satellites beyond low-Earth orbits. The computer enables researchers, businesses, and consumers broader access to space assets for their unique needs. The invention builds on the Lab's more than fifty years of experience in designing, manufacturing, and deploying instruments for use on satellites and deep space missions. A R&D 100 Award has recognized the innovation and value of the Rad-Hard SBC.

42 ENGINEERING↗

An Innovative HIV “Mosaic” Vaccine Design Based on Machine Learning

Approximately 37 million people worldwide have the human immunodeficiency virus (HIV). Because of HIV’s incredible diversity — each infected person carries a unique set of viruses — an effective vaccine against HIV needs to stimulate an immune response that can recognize its many variants. Using a machine-learning algorithm and the NIH funded Los Alamos National Laboratory database of hundreds of thousands of HIV sequences gathered from around the globe, Los Alamos scientists were able to design small sets of sequences that in combination provide optimal coverage of HIV’s diversity. The mosaic vaccine is the world’s first computationally-designed vaccine. Through a decade of testing it has continued to show promise, and so currently is being tested in two human efficacy trials to evaluate whether the investigational vaccine regimen can reduce the incidence of HIV infection among 2,600 women in sub-Saharan Africa, and 3,800 men who have sex with men and transgender people in the Americas.

59 BASIC BIOLOGICAL SCIENCES↗

Leveraging Connections 2018 Progress Report

This 2018 progress report contains a list of Los Alamos National Laboratory's top innovations of the time, including: Inventing - Los Alamos National Laboratory has been inventing for the past 75 years to accomplish the difficult, the unexpected and at times, what seems impossible. The Feynman Center is rethinking roadmaps for patent and software strategies to enable Los Alamos to achieve greater impact of its innovations; Innovating - The US technology advantage in national security is dependent on continual innovation. Los Alamos’ immense contributions in leading edge science and technology research and development are directed into solving complex and forthcoming national security challenges. Check out the Technology Snapshot platform at https://techsnapshot.lanl.gov to explore Los Alamos’s technologies ready to be developed into disruptive applications; Disrupting - Known well for developing the first nuclear weapon, big and small science at Los Alamos is behind many other disruptive innovations. This year we are highlighting Los Alamos’s leadership in small modular nuclear reactor design and development, work on international nuclear safeguards electronics instrumentation, and first demonstrated deployment of non-destructive testing to measure corrosion in nuclear material storage containers; Partnering - Los Alamos science has assisted partners big and small with their toughest challenges, this year Los Alamos scientists assisted two New Mexico farm owners—Tim Seaman with Manzanar Los Silvestres apple orchard in Abiquiu and Christopher Bassett of Freshies of New Mexico in El Guique — protect their crops from frost.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗