Thymine - A possible prebiotic synthesis
Possible prebiotic synthesis of thymine by heating uracil, paraformaldehyde and hydrazine in ammoniacal solution for three days at 70 C
Kimball, A. P.↗
Engineering topics
Kimball, A. P.
Publications and source records attributed to Kimball, A. P..
The effect of imidazole, cyanamide, and polyornithine on the condensation of nucleotides in aqueous systems.
Development of two models for the condensation of nucleotides under possibly prebiotic conditions. In the first of these models this type of reaction is promoted by the presence of imidazole and substituted imidazole compounds. The second model involves the condensation of mononucleotides with cyanamide in the presence and absence of a prototemplate such as polyornithine. A tentative mechanism for the role of imidazole catalysis in phosphodiester bond formation between adjacent TMP molecules is suggested.
Ibanez, J.↗