CRISPR-CARB/nocap
Network Optimization and Causal Analysis of Perturb-seq (NOCAP) is a software package for causal inference of gene regulation networks using data from perturb-seq.
George, August↗
Engineering topics
Hoyt, Charles Tapley
Publications and source records attributed to Hoyt, Charles Tapley.
Eliater: a Python package for estimating outcomes of perturbations in biomolecular networks
We introduce Eliater, a Python package for estimating the effect of perturbation of an upstream molecule on a downstream molecule in a biomolecular network. The estimation takes as input a biomolecular network, observational biomolecular data, and a perturbation of interest, and outputs an estimated quantitative effect of the perturbation. We showcase the functionalities of Eliater in a case study of Escherichia coli transcriptional regulatory network.
59 BASIC BIOLOGICAL SCIENCES↗