Glazier, James A. | Engineering Papers

NASA NTRS2013

Sub-micron surface plasmon resonance sensor systems

Wearable or implantable devices combining microfluidic control of sample and reagent flow and micro-cavity surface plasmon resonance sensors functionalized with surface treatments or coatings capable of specifically binding to target analytes, ligands, or molecules in a bodily fluid are provided. The devices can be used to determine the presence and concentration of target analytes in the bodily fluids and thereby help diagnose, monitor or detect changes in disease conditions.

Glazier, James A.↗

NASA NTRS2012

Sub-micron surface plasmon resonance sensor systems

A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multi-channel sensor for detecting the presence of several targets with a single microchip sensor is described. A multi-channel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets.

Glazier, James A.↗

NASA NTRS2011

Sub-micron surface plasmon resonance sensor systems

A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multi-channel sensor for detecting the presence of several targets with a single micro-chip sensor is described. A multi-channel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets.

Glazier, James A.↗

NASA NTRS2011

Sub-micron surface plasmon resonance sensor systems

A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multichannel sensor for detecting the presence of several targets with a single microchip sensor is described. A multichannel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets.

Glazier, James A.↗

NASA NTRS2010

Sub-micron surface plasmon resonance sensor systems

A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multi-channel sensor for detecting the presence of several targets with a single microchip sensor is described. A multi-channel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets.

Glazier, James A.↗

NASA NTRS2010

Sub-micron surface plasmon resonance sensor systems

A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multi-channel sensor for detecting the presence of several targets with a single micro-chip sensor is described. A multi-channel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets.

Glazier, James A.↗

NASA NTRS2004

Convective Instabilities in Liquid Foams

The main goal of this work is to better understand foam behavior both on the Earth and in microgravity conditions and to determine the relation between a foam's structure and wetness and its rheological properties. Our experiments focused on the effects of the bubble size distribution (BSD) on the foam behavior under gradual or stepwise in the liquid flow rate and on the onset of the convective instability. We were able to show experimentally, that the BSD affects foam rheology very strongly so any theory must take foam texture into account.

Veretennikov, Igor↗