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Crump, William J.

Publications and source records attributed to Crump, William J..

A systems approach to water recovery testing for space life support - Initial biomedical results from the ECLSS Water Recovery Test and plans for testbed utilization

Among the challenges of designing and constructing Space Station Freedom is the development of the water system. A review of past efforts in reclaiming waste water in enclosed environments reveals that there are many gaps in the biomedical understanding of this process. Some of the key uncertainties of human interaction with a closed water system include determining potential contaminants and establishing safe levels of multiple compounds in the enclosed system of Space Station. Another uncertainty is the microbial constituency of such a system and what impact it could have on crew health and performance. The use of iodine as the passive biocide may have both an indirect and direct impact on the crew. In this paper the initial results of the Water Recovery Test are reviewed from a biomedical perspective, revealing areas where more information is needed to develop the ECLSS water system. By including the approach of 'man as a subsystem', consideration is given to how man interacts with the total water system. Taking this systems approach to providing the crew with a safe source of water gives useful insight into the most efficient design and utilization of closed system testbeds.

Aten, Laurie A.↗

ECLSS medical support activities

During the period from April 10, 1990 to April 9, 1991, the Consortium for the Space Life Sciences provided technical assistance to the NASA/MSFC water recovery efforts. This assistance was in the form of literature reviews, technical recommendations, and presentations. This final report summarizes the activities completed during this period and identifies those areas requiring additional efforts. The tasks which the University of Alabama in Huntsville (UAH) water recovery team addressed were either identified by MSFC technical representatives or chosen from those outlined in the subject statement of work.

Crump, William J.↗

Human subjects concerns in ground based ECLSS testing - Managing uncertainty in closely recycled systems

U.S. space missions have to this point used water either made on board or carried from earth and discarded after use. For Space Station Freedom, long duration life support will include air and water recycling using a series of physical-chemical subsystems. The Environmental Control and Life Support System (ECLSS) designed for this application must be tested extensively at all stages of hardware maturity. Human test subjects are required to conduct some of these tests, and the risks associated with the use of development hardware must be addressed. Federal guidelines for protection of human subjects require careful consideration of risks and potential benefits by an Institutional Review Board (IRB) before and during testing. This paper reviews the ethical principles guiding this consideration, details the problems and uncertainties inherent in current hardware testing, and presents an incremental approach to risk assessment for ECLSS testing.

Crump, William J.↗

Environmental control medical support team

The activities conducted in support of the Environmental Control and Life Support Team during December 7, 1987 through September 30, 1988 are summarized. The majority of the ongoing support has focused on the ECLSS area. Through a series of initial meetings with the ECLSS team and technical literature review, an initial list of critical topics was developed. Subtasks were then identified or additional related tasks received as action items from the ECLSS group meetings. Although most of the efforts focused on providing MSFC personnel with information regarding specific questions and problems related to ECLSS issues, other efforts regarding identifying an ECLSS Medical Support Team and constructing data bases of technical information were also initiated and completed. The specific tasks are as follows: (1) Provide support to the mechanical design and integration of test systems as related to microbiological concerns; (2) Assist with design of Human Subjects Test Protocols; (3) Interpretation and recommendations pertaining to air/water quality requirements; (4) Assist in determining the design specifications required as related to the Technical Demonstration Program; (5) Develop a data base of all microorganisms recovered from previous subsystem testing; (6) Estimates of health risk of individual microbes to test subjects; (7) Assist with setting limits for safety of test subjects; (8) Health monitoring of test subjects; (9) Assist in the preparation of test plans; (10) Assist in the development of a QA/QC program to assure the validity, accuracy and precision of the analyses; and (11) Assist in developing test plans required for future man in the loop testing.

Crump, William J.↗