Engineering topics

Clement, Gilles

Publications and source records attributed to Clement, Gilles.

23 records · Page 2

NASA NTRS1999

Low-Frequency Otolith Function in Microgravity: A Re-Evaluation of the Otolith Tilt-Translation Reinterpretation (OTTR) Hypothesis

On Earth, the low-frequency afferent signal from the otoliths encodes head tilt with respect to the gravitational vertical, and the higher frequency components reflect both tilt and linear acceleration of the head. In microgravity, static tilt of the head does not influence otolith output, and the relationship between sensory input from the vestibular organs, and the visual, proprioceptive and somatosensory systems, would be disrupted. Several researchers have proposed that in 0-g this conflict may induce a reinterpretation of all otolith signals by the brain to encode only linear translation (otolith tilt-translation reinterpretation or OTTR). Ocular counter-rolling (OCR) is a low-frequency otolith-mediated reflex, which generates compensatory torsional eye movements (rotation about the visual axis) towards the spatial vertical during static roll tilt with a gain of approximately 10%. Transient linear acceleration and off-axis centrifugation at a constant angular velocity can also generate OCR. According to the OTTR hypothesis, OCR should be reduced in microgravity, and immediately upon return from a 0-g environment. Results to date have been inconclusive. OCR was reduced following the 10 day Spacelab-1 mission in response to leftward roll tilts (28-56% in 3 subjects and unchanged in one subject), and sinusoidal linear oscillations at 0.4 and 0.8 Hz. OCR gain declined 70% in four monkeys following a 14 day COSMOS mission. Following a 30 day MIR mission OCR gain decreased in one astronaut, but increased in two others following a 180 day mission. We have studied the affect of microgravity on low-frequency otolith function as part of a larger study of the interaction of vision and the vestibular system. This experiment (E-047) involved off-axis centrifugation of payload crewmembers and flew aboard the recent Neurolab mission (STS 90). Presented below are preliminary results focusing on perception and the OCR response during both centrifugation and static tilt.

Moore, Steven T.↗

NASA NTRS1996

Spatial Transformation of the Vestibulo-Ocular Reflex during Spaceflight

It was hypothesized that the absence of the gravitational reference cues may be responsible for adaptive changes in the vestibulo-ocular reflex (VOR). These changes result in the alteration of the direction of the compensatory slow phase (SP) eye movements in microgravity. In order to test this hypothesis, the direction of the VOR SP relative to head motion was investigated in three astronauts during and after an eight-day orbital flight by passive sinusoidal pitch or yaw angular motion at two frequencies. The results of the inflight and postflight testing are considered. The observed deviation between VOR SP and head motion suggests that spatial transformation in the VOR occurred during adaptation to microgravity. It is considered that, although this spatial transformation might be due to a sensory bias, it may reflect central changes in the reference system used for spatial orientation in microgravity.

Clement, Gilles↗

NASA NTRS1993

Up-down asymmetry of vertical optokinetic nystagmus and after-nystagmus elicited in microgravity

Vertical optokinetic nystagmus (OKN) and optokinetic after-nystagmus (OKAN) studied in 4 subjects during parabolic flights were compared with data obtained on 2 subjects before, during, and after a 7-day space shuttle flight. In parabolic flight, the vertical OKAN following upgoing optokinetic stimulation increased during the 0 g phase, and decreased during the 1.8 g phase. In spaceflight, the vertical OKN gain asymmetry showed a reversal during early exposure to microgravity. This asymmetry reversal is likely the same effect seen in parabolic flight and could be a direct response to the change in otolithic output. However, if asymmetry changes were due only to the otolithic sensory input, we would also expect large changes upon return to normal gravity. Instead, there were large OKN and OKAN changes at the beginning of the flight, but the deviation from the original vertical OKN gain asymmetry constantly decreased throughout the flight and continued post-flight until pre-flight asymmetry value was restored. This suggests one adaptive goal which reinstates the original pre-flight gain and asymmetry value regardless of changing inputs. This adaptation resembles mechanisms seen in posture experiments where the motor programs on Earth are reinstated in microgravity after a period of adjustment.

Clement, Gilles↗

NASA NTRS1992

Effects of gravitoinertial force variations on optokinetic nystagmus and on perception of visual stimulus orientation

Recordings of horizontal and vertical eye movement were obtained with subjects exposed to vertical, horizontal, and oblique optokinetic stimulation during parabolic flight. When the optokinetic stimulation was vertical, the upward slow phase eye velocity increased increased during transition from high force level to free-fall, and decreased during transition from free-fall to high force level. During optokinetic stimulation in the horizontal and oblique plane, the gravitoinertial forces of parabolic flight induced changes in the velocity of the vertical component of the eye movements, and, therefore, changes in the plane of the eye movements. Some subjects also preceived modifications in the apparent orientation of the visual motion. These findings are in agreement with previous observations on the presence of a vertical nystagmus induced by changes in plane vertical acceleration. They also suggest a close interaction of reflexive eye movements induced by graviceptor inputs and visual inputs for visual stabilization during variations of gravitoinertial force level.

Clement, Gilles↗

NASA NTRS1992

Effects of microgravity on the interaction of vestibular and optokinetic nystagmus in the vertical plane

The extent to which the slow phase velocity (SPV) of nystagmus elicited by a vertical optokinetic stimulation with constant velocity could be modulated by sinusoidal angular motion in the vertical plane was investigated under normal gravity condition and during the microgravity period of parabolic flight. In normal gravity, when the angular head motion and the optokinetic stimulation were in the same direction, the peak SPV was slower than the velocity of the optokinetic display. When the head motion and the optokinetic stimulation were in opposite directions, the peak SPV was equal to the velocity of the optokinetic display. In microgravity, the peak SPV was approximately equal to the velocity of the optokinetic display when head rotation and optokinetic stimulation were in the same direction, and was faster than the velocity of the optokinetic dispaly when head rotation and optokinetic stimulation were in opposite directions. In addition, the interaction of vestibular and optokinetic nystagmus was found to be nonlinear in microgravity, especially when the optokinetic stimulation was directed downward. These results suggest an interaction between the vestibular and the optokinetic systems modulated as a function of the gravitational state, and support the observation that visual input is more effective in reducing sensory conflict experienced in microgravity.

Clement, Gilles↗