Network Topology Evaluation and Transitive Alignments for Molecular Networking
Not provided.
Biochemistry & Molecular Biology↗
Engineering topics
Brown, Christopher
Publications and source records attributed to Brown, Christopher.
NRAP Recommended Practices for Containment Assurance and Leakage Risk Quantification
This report presents recommendations for quantitatively assessing and managing leakage risk and effective containment assurance at geologic carbon storage (GCS) sites, amidst uncertainty in site characteristics and performance. These recommended practices are a product of the U.S. Department of Energy’s (DOE) Office of Fossil Energy and Carbon Management’s National Risk Assessment Partnership (NRAP)—a multi-year collaborative research effort of Lawrence Berkeley National Laboratory, Lawrence Livermore National Laboratory, Los Alamos National Laboratory, National Energy Technology Laboratory, and Pacific Northwest National Laboratory. These recommended practices are organized as a set of conceptual workflows that correspond with the stages of the GCS project lifecycle. They consider aspects of site characterization, quantification of potential leakage, assessing the spatial extent of potential environmental impacts, optimizing monitoring design for detection of potential leakage, evaluation of concordance between monitored and forecasted reservoir response, assessing conformance with expected/accepted performance, and determination of the timeline over which risk of impactful leakage can be expected to abate. These conceptual workflows are intended to aid stakeholders in making risk management decisions at GCS sites and to support development of sound, risk-based justifications for characterizing the subsurface, defining area of potential leakage impact, designing site monitoring plans, selecting leakage risk management/mitigation alternatives, and estimating site closure timelines.
54 ENVIRONMENTAL SCIENCES↗
Computational Tools and Workflows for Quantitative Risk Assessment and Decision Support for Geologic Carbon Storage Sites: Progress and Insights from the U.S. DOE’s National Risk Assessment Partnership
The 2005 Intergovernmental Panel on Climate Change (IPCC) Special Report on CCS raised the profile of CO2 capture and storage (CCS) as an important technology for reducing greenhouse gas (GHG) emissions. CCS is now recognized as a key component of most climate change mitigation scenarios. Since publication of that report the international research, development, and deployment (RD&D) community has advanced key technical aspects, clarified regulatory requirements, explored value chain and infrastructure solutions, and developed incentive paradigms to enable and promote large-scale deployment of CCS. These efforts have included research to better characterize geologic storage resources, to improve injection performance and storage efficiency, to assess and manage subsurface environmental risks, and to advance monitoring technologies to assure system conformance. These efforts have helped to build confidence in the viability of geologic carbon storage (GCS), but stakeholder concerns about long-term risks and liability associated with GCS remain a hurdle to broad acceptance and large-scale deployment of CCS. Since 2010, the U.S. DOE’s National Risk Assessment Partnership (NRAP) – a research collaboration between five contributing national laboratories – has worked to establish and demonstrate methods and tools to quantify and manage the subsurface environmental risks associated with GCS, amidst uncertainty. This work supports the Office of Fossil Energy and Carbon Management Carbon Transport and Storage Program’s goal of advancing safe and secure commercial-scale GCS deployment. To address the technical challenge of simulating the physical response of the GCS site to large-scale CO2 injection, NRAP has adopted an approach that relies on coupling computationally efficient reduced-order and/or data-driven proxy models of important system components (i.e., storage reservoir, sealing caprock, leakage pathways, intermediate formations, overlying groundwater aquifers, and the atmosphere) in integrated assessment framework. That integrated model of the physical system is complemented with fit-for purpose functionality to support site characterization and risk-related decisions. The recently released NRAP Phase II toolset includes the Open-Source Integrated Assessment Model (NRAP-Open-IAM) for evaluation of trends in leakage risk and potential impact, tools to support monitoring design optimization (Designs for Risk Evaluation and Management – DREAM v3.0 and Passive Seismic Monitoring Tool - PSMT), and tools for state of stress evaluation (State-of-Stress Analysis Tool - SOSAT) and forecasting induced seismicity risk. The NRAP team has also released a pair of reports describing conceptual workflows to incorporate physics-based, quantitative risk assessment into many of the design, planning, operation, and closure decisions for GCS projects. An online catalogue highlights published studies where these tools and methods are demonstrated. In this presentation, the utility of these products to assess risks and address key stakeholder questions will be highlighted through examples, and related insights about the safety and security of geologic carbon storage in qualified storage sites will be discussed. The prospect of rapid, large-scale deployment of GCS technology to aggressively reduce anthropogenic CO2 emissions requires careful consideration of interference between multiple commercial-scale storage projects within a basin. Going forward, NRAP is expanding and adapting site-scale risk quantification tools and methods to enable assessment of risks and inform management decisions for basin-scale deployment. Increasingly, this work will leverage next-generation approaches for surrogate modelling, fast prediction, and advanced visualization enabled by machine learning and artificial intelligence to promote virtual learning, scenario evaluation, and augment risk-based decision making.
quantitative risk assessment, geologic carbon stor↗
Integrating Risk Assessment Methods for Carbon Storage: A Case Study for the Quest Carbon Capture and Storage Facility
2022 Carbon Management Project Review Meeting, Pittsburgh, PA, August 15-19, 2022
Lackey, Greg↗
Report on High Energy Arcing Fault Experiments: Experimental Results from Low-Voltage Switchgear Enclosures
This report documents an experimental program designed to investigate High Energy Arcing Fault (HEAF) phenomena for low-voltage metal enclosed switchgear containing aluminum conductors. This report covers full-scale laboratory experiments using representative nuclear power plant (NPP) three-phase electrical equipment. Electrical, thermal, and pressure data were recorded for each experiment and documented in this report. This report covers experiments performed on two low-voltage switchgear units with each unit consisting of two vertical sections. The data collected supports characterization of the low-voltage HEAF hazard and these results will be used to support potential improvements in fire probabilistic risk assessment (PRA) methods. The experiments were performed at KEMA Labs located in Chalfont, Pennsylvania. The experimental design, setup, and execution were completed by staff from the NRC, the National Institute of Standards and Technology (NIST), Sandia National Laboratories (SNL) and KEMA. In addition, representatives from the Electric Power Research Institute (EPRI) observed some of the experimental setup and execution. The HEAF experiments were performed between August 26 and Augsut 29, 2019 on nearidentical Westinghouse Type DS low-voltage metal-enclosed indoor switchgear. The threephase arcing fault was initiated on the aluminum main bus or in select cases on the copper bus stabs near the breaker. These experiments used either nominal 480 volts AC or 600 volts AC. Durations of the experiments ranged from approximately 0.4 s to 8.3 s with fault currents ranging from approximately 9.2 kA to 19.3 kA. Real-time electrical operating conditions, including voltage, current and frequency, were measured during the experiments. Heat fluxes and incident energies were measured with plate thermometers, radiometers, and slug calorimeters at various locations around the electrical enclosures. Environmental measurements of breakdown, conductivity and electromagnetics were also taken. The experiments were documented with normal and high-speed videography, infrared imaging and photography. The results, while limited, indicated the difficulty in maintaining and sustaining low-voltage arcs on aluminum components of sufficient duration and at a single point as observed operating experience.
22 GENERAL STUDIES OF NUCLEAR REACTORS↗
Report on High Energy Arcing Fault Experiments: Experimental Results from Open Box Enclosures
This report documents an experimental program designed to investigate High Energy Arcing Fault (HEAF) phenomena. The experiments focus on providing data to better characterize the arc to improve the prediction of arc energy emitted during a HEAF event. An open box experiment allow for direct observation of the arc, which allows diagnostic instrumentation to record the phenomenological data needed for better characterization of the arc energy source term. The data collected supports characterization of the arc and arc jet, enclosure breach, material loss, and electrical properties. These results will be used to better characterizing the hazard for improvements in fire probabilistic risk assessment (PRA) realism. The experiments were performed at KEMA Labs located in Chalfont, Pennsylvania. The experimental design, setup, and execution were completed by staff from the NRC, the National Institute of Standards and Technology (NIST), Sandia National Laboratories (SNL) and KEMA Labs. In addition, representatives from the Electric Power Research Institute (EPRI) observed some of the experimental setup and execution. The HEAF experiments were performed between August 22, 2020 and September 18, 2020 on near-identical 51 cm (20 in) cube metal boxes suspended from a Unistrut support structure. The three-phase arcing fault was initiated at the ends of the conductors oriented vertically and located at the center of the box. Either aluminum or copper conductors were used for the conductors. The low-voltage experiments used 1 000 volts AC, while the medium-voltage experiments used 6 900 volts AC consistent with other recently completed experiments. Durations of the experiment ranged from 1 s to 5 s with fault currents ranging from 1 kA to 30 kA. Real-time electrical operating conditions, including voltage, current and frequency, were measured during the experiments. Heat fluxes and incident energies were measured with plate thermometers, radiometers, and slug calorimeters at various locations around the electrical enclosures. The experiments were documented with normal and high-speed videography, infrared imaging and photography.
21 SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS↗
An Inhibitor-in-Pieces Approach to DAHP Synthase Inhibition: Potent Enzyme and Bacterial Growth Inhi
Explore the source record for details and available documents.
Heimhalt, Maren↗
Report on High Energy Arcing Fault Experiments
This report documents an experimental program designed to investigate High Energy Arcing Fault (HEAF) phenomena for medium voltage electrical switchgear containing aluminum conductors. This report covers full-scale laboratory experiments using representative nuclear power plant (NPP) three-phase electrical equipment. Electrical, thermal, and pressure data were recorded for each experiment and documented in this report. This report covers four of the fourteen planned medium voltage electrical enclosure experiments. Subsequent reports will document the additional experiments performed in the future. The experiments were performed at KEMA Labs located in Chalfont, Pennsylvania. The experimental design, setup, and execution were completed by staff from the United States Nuclear Regulatory Commission (NRC), the National Institute of Standards and Technology (NIST), Sandia National Laboratories (SNL) and KEMA. In addition, representatives from the Electric Power Research Institute (EPRI) observed some of the experimental setups and execution. The HEAF experiments were performed on four near-identical units of General Electric metal-clad medium voltage switchgear. The three-phase arcing fault was initiated on the primary cable connection bus. All four experiments used the same system voltage (6.9 kV) but varied the current and duration. Real-time electrical operating conditions, including voltage, current and frequency, were measured during the experiments. Heat fluxes and incident energies were measured with plate thermometers and slug calorimeters at various locations around the electrical enclosures. Internal enclosure pressures were measured during the experiments. The experiments were documented with normal and high-speed videography, infrared imaging, and photography. Insights from the experimental series included timing information related to enclosure breach, event progression, mass loss measurements for electrodes and steel enclosures, peak pressure rise, particle analysis, along with visual and thermal imaging data to better understand and characterize the hazard. These results will be used in subsequent efforts to advance the state of knowledge related to HEAF.
42 ENGINEERING↗
Status of ISS Water Management and Recovery
Water management on ISS is responsible for the provision of water to the crew for drinking water, food preparation, and hygiene, to the Oxygen Generation System (OGS) for oxygen production via electrolysis, to the Waste & Hygiene Compartment (WHC) for flush water, and for experiments on ISS. This paper summarizes water management activities on the ISS US Segment and provides a status of the performance and issues related to the operation of the Water Processor Assembly (WPA) and Urine Processor Assembly (UPA). This paper summarizes the on-orbit status as of June 2017 and describes the technical challenges encountered and lessons learned over the past year.
Carter, Layne↗
Status of ISS Water Management and Recovery
Water management on ISS is responsible for the provision of water to the crew for drinking water, food preparation, and hygiene, to the Oxygen Generation System (OGS) for oxygen production via electrolysis, to the Waste & Hygiene Compartment (WHC) for flush water, and for experiments on ISS. This paper summarizes water management activities on the ISS US Segment, and provides a status of the performance and issues related to the operation of the Water Processor Assembly (WPA) and Urine Processor Assembly (UPA). This paper summarizes the on-orbit status as of June 2013, and describes the technical challenges encountered and lessons learned over the past year.
Carter, Layne↗
Utilizing NX Advanced Simulation for NASA's New Mobile Launcher for Ares-l
This slide presentation reviews the use of NX to simulate the new Mobile Launcher (ML) for the Ares-I. It includes: a comparison of the sizes of the Saturn 5, the Space Shuttle, the Ares I, and the Ares V, with the height, and payload capability; the loads control plan; drawings of the base framing, the underside of the ML, beam arrangement, and the finished base and the origin of the 3D CAD data. It also reviews the modeling approach, meshing. the assembly Finite Element Modeling, the model summary. and beam improvements.
Brown, Christopher↗
Starch Metabolism in Space-Grown Soybean Seedlings
The research conducted during this grant is described. There were three major areas of study: These were: (1) the interaction of gravity and sugar metabolism in soybean; (2) the effects of gravity on the photosynthetic activity of Brassica rapa; (3) investigation as to the effects of microgravity on the interaction of a fungal root pathogen with soybean.
Guikema, James A.↗
Starch Metabolism in Space-Grown Soybean Seedlings
The focus of this research was the study of sugar metabolism in soybean plants that had been in a clinorotation condition. The scope of activities was broadened greatly after the onset of the award. This broadening added two major research foci: 1) B-PAC: Photosynthetic activity of Brassica rapa; and 2) SOYPAT: The effects of microgravity on the interaction of a fungal root pathogen with soybean. Substantial investment and activity was also focused on the training of the astronaut team to conduct these experiments during orbital spaceflight.
Guikema, James A.↗
Conceptual design of an Orbital Debris Defense System
Man made orbital debris has become a serious problem. Currently NORAD tracks over 7000 objects in orbit and less than 10 percent of these are active payloads. Common estimates are that the amount of debris will increase at a rate of 10 percent per year. Impacts of space debris with operational payloads or vehicles is a serious risk to human safety and mission success. For example, the impact of a 0.2 mm diameter paint fleck with the Space Shuttle Challenger window created a 2 mm wide by 0.6 mm deep pit. The cost to replace the window was over $50,000. A conceptual design for a Orbital Debris Defense System (ODDS) is presented which considers a wide range of debris sizes, orbits and velocities. Two vehicles were designed to collect and remove space debris. The first would attach a re-entry package to de-orbit very large debris, e.g. inactive satellites and spent upper stages that tend to break up and form small debris. This vehicle was designed to contain several re-entry packages, and be refueled and resupplied with more re-entry packages as needed. The second vehicle was designed to rendezvous with and capture debris ranging from 10 cm to 2 m. Due to tracking limitations, no technically feasible method for collecting debris below 10 cm in size could be devised; it must be accomplished through international regulations which reduce the accumulation of space debris.
Bedillion, Erik↗