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Beer, N. Reginald

Publications and source records attributed to Beer, N. Reginald.

At least 19 records

Swarm path planner system for vehicles

A system for determining optimal paths without collision through a travel volume for a swarm of vehicles is disclosed. The system determines a travel path for the swarm leader vehicle using a minimal cost path derived from various measures of environmental cost for avoiding objects in traveling from leader location to target location. The system also determines, for each empty neighbor location of each follower vehicle, relational costs for follower vehicle travel relative to leader vehicle travel. The various measures of relational cost seek to maintain a prescribed positional relationship between each follower vehicle and the leader vehicle given the leader vehicle travel path. Based on various measures of environmental and relational cost, the system determines the best travel path for the each follower vehicle relative to the leader vehicle.

Paglieroni, David W.↗

Collision avoidance based on traffic management data

A system for determining a travel direction that avoids objects when a vehicle travels from a current location to a target location is provided. The system determines a travel direction based on an attract-repel model. The system accesses external object information provided by an external object system. The external object information may include, for each of a plurality of objects, location, type, and constraint. The system assigns a repel value to the location of each object based on the type of and constraint on the object. The system assigns an attractive value to the target location. The system calculates a cumulative force based on the attractive and repulsive forces and sets the travel direction based on the cumulative force.

Beer, N. Reginald↗

Integrated solid-state rapid thermo-cycling system

Techniques, systems, and devices are disclosed for implementing a portable lab system for PCR testing. An example method for operating an integrated thermal cycling system includes depositing samples into the integrated thermal cycling system that includes a thermal cycling device and an electronic interface. The thermal cycling device includes multiple wells to receive the samples to be thermally cycled, a thermoelectric cooling (TEC) element connected to the multiple wells, a substrate on which the TEC element is positioned, and a controller coupled to the TEC element. The multiple wells are positioned within the substrate that includes a thermally conductive ground positioned between adjacent wells. Supplying power to the integrated thermal cycling system, via the electronic interface, allows the multiple wells to exchange heat with the substrate and for each well to operate independently from other wells.

Beer, N. Reginald↗

Object sense and avoid system for autonomous vehicles

A system for determining a travel path for an autonomous vehicle (“AV”) to travel to a target while avoiding objects (i.e., obstacles) without the use of an imaging system is provided. An object sense and avoid (“OSA”) system detects objects in an object field that is adjacent to the AV and dynamically generates, as the AV travels, a travel path to the target to avoid the objects. The OSA system repeatedly uses sensors to collect sensor data of any objects in the object field. An object detection system then detects the objects and determines their locations based on triangulating ranges to an object as indicated by different sensors. The path planner system then plans a next travel direction for the AV to avoid the detected objects while seeking to minimize the distance traveled. The OSA system then instructs the AV to travel in the travel direction.

Beer, N. Reginald↗

Solid-state integrated real-time optical monitoring of biochemical assays

The disclosed technology includes a planar device for performing multiple biochemical assays at the same time, or nearly the same time. Each assay may include a biosample including a biochemical, enzyme, DNA, and/or any other biochemical or biological sample. Each assay may include one or more tags including dyes and/or other chemicals/reagents whose optical characteristics change based on chemical characteristics of the biological sample being tested. Each assay may be optically pumped to cause one or more of luminescence, phosphorescence, or fluorescence of the assay that may be detected by one or more optical detectors. For example, an assay may include two tags and a biosample. Each tag may be pumped by different wavelengths of light and may produce different wavelengths of light that is filtered and detected by one or more detectors. The pump wavelengths may be different from one another and different from the produced wavelengths.

Beer, N. Reginald↗

Autonomous sense and guide machine learning system

A system for generating a machine learning system to generate guidance information based on locations of objects is provided. The system accesses training data that includes training time-of-arrival (“TOA”) information of looks and guidance information for each look. The guidance information is based on a training collection of object locations. The TOA of a look represents, for each object location of a training collection of object locations, times between signals transmitted by transmitters and return signals received by receivers. The return signals represent signals reflected from an object at the object location. The system trains a machine learning system using the training data wherein the machine learning system inputs TOA information and outputs guidance information.

Beer, N. Reginald↗

UAV ground penetrating radar array

A GPR system the implements a modified multistatic mode of operation is provided. The GPR is suitable for mounting on an unmanned aerial vehicle. The GPR system has radar transceivers. The GPR system transmits transmit signal serially via the transceivers. For each transceiver that transmits a transmit signal, the GPR system receives a return signal acquired by each transceiver except for a return signal for the transceiver that transmits the transmit signal. The GPR system outputs of matrix of return signals that includes a null value for the return signals of the transceivers that transmit.

Beer, N. Reginald↗

Attract-repel path planner system for collision avoidance

A system for determining a travel direction that avoids objects when a vehicle travels from a current location to a target location is provided. The system determines a travel direction based on an attract-repel model. The system assigns a repel value to the object locations and an attract value. A repel represents a magnitude of a directional repulsive force, and the attract value represents the magnitude of a directional repulsive force. The system calculates an attract-repel field having an attract-repel magnitude and attract-repel direction for the current location based on the repel values and their directions and the attract value and its direction. The system then determines the travel direction for a vehicle to be the direction of the attract-repel field at the current location.

Paglieroni, David W.↗

Electrical sensing, tracking, and actuation of droplets

Devices, techniques, and processes are disclosed that use electrical impedance to detect of the presence and contents of droplets including cells, nucleic acids, proteins, or solute concentrations in an array of retrievable, trackable, trapped droplets in a fluidic system. Electrodes may be positioned underneath individual droplet traps in a microchannel to assay droplet contents and/or actuating droplets for the release of the droplets from corresponding traps. The disclosed technology may be used for detection of the results of solvent extraction processes including time-dependent quantification of metal ion concentration in the aqueous and organic phases, for wastewater treatment, heavy metal detection, pharmaceutical industry, and/or biotechnology, or for environmental monitoring of wastewater for toxic metal, monitoring of biological cell viability and proliferation, monitoring of extraction processes used in heavy metal mining, monitoring of extraction processes used in nuclear fuel processing, monitoring kinetics of enzyme processes, and/or assessing pharmacodynamics and drug efficacy.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Integrated solid-state rapid thermo-cycling system

Techniques, systems, and devices are disclosed for implementing a portable lab system for PCR testing. The portable lab system comprises a thermal cycling device including a first well and a second well to receive samples to be thermally cycled, a thermoelectric cooling (TEC) element coupled to the first well and the second well, and a controller to control operation of the TEC element. The portable lab system further includes an electronic interface including a power interface to supply power to the TEC element and the controller of the thermal cycling device to allow the TEC element to transfer energy from the first well to the second well when current flows through the TEC element in a first direction, and from the second well to the first well when current flows through the TEC element in a second direction, and a data interface to collect data from the controller.

59 BASIC BIOLOGICAL SCIENCES↗

Solid-state integrated real-time optical monitoring of biochemical assays

The disclosed technology includes a planar device for performing multiple biochemical assays at the same time, or nearly the same time. Each assay may include a biosample including a biochemical, enzyme, DNA, and/or any other biochemical or biological sample. Each assay may include one or more tags including dyes and/or other chemicals/reagents whose optical characteristics change based on chemical characteristics of the biological sample being tested. Each assay may be optically pumped to cause one or more of luminescence, phosphorescence, or fluorescence of the assay that may be detected by one or more optical detectors. For example, an assay may include two tags and a biosample. Each tag may be pumped by different wavelengths of light and may produce different wavelengths of light that is filtered and detected by one or more detectors. The pump wavelengths may be different from one another and different from the produced wavelengths.

Beer, N. Reginald↗

Droplet array for single-cell analysis

Techniques, systems, and devices are described for implementing a droplet array for single-cell analysis. A method of conducting single-cell analysis comprises generating a plurality of droplets, wherein each of the plurality of droplets contains a core material surrounded by a protective shell; loading the plurality of droplets, via a carrying fluid, onto an array including a plurality of trap structures, wherein the plurality of droplets are held by the plurality of trap structures; selecting a target droplet, held by a trap structure, from the plurality of droplets; and releasing the target droplet from the trap structure.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Object discrimination based on a swarm of agents

A configuration system for identifying a target configuration of agents for acquiring data is provided. In some embodiments, the configuration system generates sample configurations, each of which has a location within the space for each agent. The configuration system selects as the target configuration a sample configuration that is suitable to acquire data. The configuration system selects the target configuration by, for at least one or more sample configurations, directing that the agents assume the sample configuration and then acquire data when in the sample configuration. The configuration system then stores, for each sample configuration, an indication of suitability for acquiring data based on the sample configuration. The configuration system selects a sample configuration that is deemed to be suitable as the target configuration.

Beer, N. Reginald↗

System for detecting objects in streaming 3D images formed from data acquired with a medium penetrating sensor

A detection system that detects subsurface objects within a medium and estimates various features of the objects is provided. The detection system receives a streaming sequence of image frames of the medium at various along-medium locations. An image frame contains voxel values (intensities) representing characteristics of the medium across the medium and in the depth (range) direction. The detection system depth-compensates the intensities for determining which voxels are part of an object using an unsupervised binary classifier. The detection system then connects object voxels into distinct objects and recursively estimates the features of those objects as the image frames stream based on the locations and intensities of the object voxels.

Paglieroni, David W.↗

Imaging, object detection, and change detection with a polarized multistatic GPR array

A polarized detection system performs imaging, object detection, and change detection factoring in the orientation of an object relative to the orientation of transceivers. The polarized detection system may operate on one of several modes of operation based on whether the imaging, object detection, or change detection is performed separately for each transceiver orientation. In combined change mode, the polarized detection system performs imaging, object detection, and change detection separately for each transceiver orientation, and then combines changes across polarizations. In combined object mode, the polarized detection system performs imaging and object detection separately for each transceiver orientation, and then combines objects across polarizations and performs change detection on the result. In combined image mode, the polarized detection system performs imaging separately for each transceiver orientation, and then combines images across polarizations and performs object detection followed by change detection on the result.

47 OTHER INSTRUMENTATION↗

Change Detection in Constellations of Buried Objects Extracted From Ground-Penetrating Radar Data

Detection of deliberately buried objects in ground-penetrating radar (GPR) data acquired along a path is a clutter-limited problem. Detection-false alarm rate performance can be improved by replacing the detection statistic with a change statistic that incorporates information from previous path traversals. A constellation matching approach is developed for buried-object change detection in GPR data. Network topologies of buried objects detected in GPR data from previous path traversals are maintained in a constellation database. Localized groups of buried objects newly detected on the latest path traversal are matched to the constellation. Buried objects from the latest path traversal whose locations or strengths cannot be reconciled with the constellation are identified as changes. The system has one component that generates constellation databases offline and another component suitable for change detection in real time. It can tolerate paths with significant translational misalignments. The system uses the following: 1) a customized translational relaxation algorithm for point pattern matching that incorporates detection strength and a probabilistic uncertainty model for buried-object location into the objective function and 2) a change statistic that accounts for the magnitude of change relative to predicted detection strength. A constellation database can typically be generated offline from a single path traversal roughly two orders of magnitude faster than the time typically required for a vehicle to travel the extent of the path. Database sizes are typically four to five orders of magnitude smaller than the data sets of GPR signal scans or focused 3-D GPR images that they were generated from. On bumpy dirt roads buried exclusively with nonmetallic objects at various depths, detection-false alarm rate performance is shown to be significantly better for our change statistics than for our detection statistics.

47 OTHER INSTRUMENTATION↗

Spot restoration for GPR image post-processing

A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes the return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object.

47 OTHER INSTRUMENTATION↗

Distributed road assessment system

A system that detects damage on or below the surface of a paved structure or pavement is provided. A distributed road assessment system includes road assessment pods and a road assessment server. Each road assessment pod includes a ground-penetrating radar antenna array and a detection system that detects road damage from the return signals as the vehicle on which the pod is mounted travels down a road. Each road assessment pod transmits to the road assessment server occurrence information describing each occurrence of road damage that is newly detected on a current scan of a road. The road assessment server maintains a road damage database of occurrence information describing the previously detected occurrences of road damage. After the road assessment server receives occurrence information for newly detected occurrences of road damage for a portion of a road, the road assessment server determines which newly detected occurrences correspond to which previously detected occurrences of road damage.

47 OTHER INSTRUMENTATION↗